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Recombinant Human IL-6R Protein
- 种属: 人(Human)
- Accession #: NP_000556.1, P08887
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.
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Recombinant Human IL-6R alpha Protein
- 种属: 人(Human)
- Accession #: P08887
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Immobilized Recombinant Human IL-6R alpha Protein (rp181252) at 2.0 μg/mL can bind Recombinant Human IL-6 Protein (rp156005) with the EC50 of 43.35 ng/mL. 2. Immobilized Recombinant Human IL-6R alpha Protein (rp181252) at 1.0 μg/mL can bind Vobarilizumab (anti-IL-6Ra) (Ab175700) with the EC50 of 67.99 ng/mL. 3. Immobilized Recombinant Human IL-6R alpha Protein (rp181252) at 1.0 μg/mL can bind Tocilizumab (anti-IL-6R) (T412004) with the EC50 of 21.05 ng/mL.
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Recombinant Mouse IL-6R alpha Protein
- 种属: 小鼠(Mouse)
- Accession #: P22272
- 表达系统: HEK293
- 蛋白标签: C-10His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse IL-6 Protein is immobilized at 2.00 μg/mL, 100 μL/well, Recombinant Mouse IL-6R alpha Protein binds with an ED50 of 30.0-300 ng/mL.
