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分子生物学
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Recombinant Human IL-12 Protein
- 种属: 人(Human)
- Accession #: P29460,P29459
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. The ED50 for this effect is 0.01-0.05 ng/mL. Immobilized Recombinant Human IL-12 protein (rp156174) at 1.0 μg/mL can bind Ebdarokimab (anti-IL-12B) (Ab182919) with the EC50 of 9.68 ng/mL.
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Recombinant Human IL-12/IL-23 p40 Protein
- 种属: 人(Human)
- Accession #: P29460
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Immobilized Recombinant Human IL-12/IL-23 p40 Protein (rp181556) at 1.0 μg/mL can bind Briakinumab (anti-IL-12) (Ab175480) with the EC50 of 17.82 ng/mL.
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Recombinant Mouse CD47 Protein
- 种属: 小鼠(Mouse)
- Accession #: NP_034711
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha /CD172a Fc Chimera is coated at 2 μg/mL, Recombinant Mouse CD47 binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha /CD172a Fc Chimera. The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.
