代谢酶/蛋白酶 - 按“信号通路”分类 - 小分子和化合物库

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4-羟基三苯氧胺

规格或纯度 :

≥98%
E:Z isomers=50:50

CAS号: 68392-35-8

分子式: C₂₆H₂₉NO₂ 分子量: 387.51

IUPAC Name: 4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

SMILES: CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3

InChIKey: TXUZVZSFRXZGTL-QPLCGJKRSA-N

InChI: 1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-

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Avadomide

规格或纯度 :

Moligand™

≥99%

CAS号: 1015474-32-4

分子式: C₁₄H₁₄N₄O₃ 分子量: 286.29

IUPAC Name: 3-(5-amino-2-methyl-4-oxoquinazolin-3-yl)piperidine-2,6-dione

SMILES: CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N

InChIKey: RSNPAKAFCAAMBH-UHFFFAOYSA-N

InChI: 1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)

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PROTAC SGK3降解剂-1

规格或纯度 :

≥98%

CAS号: 2381320-35-8 Compound CID : 139035049

分子式: C₅₇H₇₃FN₁₀O₁₁S₂ 分子量: 1157.38

IUPAC Name: (2S,4R)-1-[(2S)-2-[[2-[2-[2-[6-[(2R)-2-[[6-[4-[(2-fluoro-5-methylphenyl)sulfonylamino]phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxymethyl]morpholin-4-yl]hexoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbSee more

SMILES: CC1=CC(=C(C=C1)F)S(=O)(=O)NC2=CC=C(C=C2)C3=NC4=C(C=NN4)C(=N3)OCC5CN(CCO5)CCCCCCOCCOCCOCC(=O)NC(C(=O)N6CC(CC6C(=O)NCC7=CC=C(C=C7)C8=C(N=CS8)C)O)C(C)(C)C

InChIKey: RTFQFPZKDYMMMJ-RIAKQDHQSA-N

InChI: 1S/C57H73FN10O11S2/c1-37-10-19-46(58)48(28-37)81(73,74)66-42-17-15-41(16-18-42)52-63-53-45(31-61-65-53)55(64-52)79-34-44-33-67(21-23-78-44)20-8-6-7-9-22-75-24-25-76-26-27-77-35-49(70)62-51(57(3,4)5)56See more

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VH 298

规格或纯度 :

10mM in DMSO

CAS号: 2097381-85-4 Compound CID : 122199236

分子式: C₂₇H₃₃N₅O₄S 分子量: 523.65

IUPAC Name: (2S,4R)-1-[(2S)-2-[(1-cyanocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)C4(CC4)C#N)O

InChIKey: NDVQUNZCNAMROD-RZUBCFFCSA-N

InChI: 1S/C27H33N5O4S/c1-16-21(37-15-30-16)18-7-5-17(6-8-18)12-29-23(34)20-11-19(33)13-32(20)24(35)22(26(2,3)4)31-25(36)27(14-28)9-10-27/h5-8,15,19-20,22,33H,9-13H2,1-4H3,(H,29,34)(H,31,36)/t19-,20+,22-/m1/sSee more

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Emicizumab (anti-Factor IX)

规格或纯度 :

≥95%(SDS-PAGE&SEC-HPLC)
见COA

应用:

Animal Model
ELISA
Flow Cytometry
Functional Assay

关联靶标: F10 F9

简短描述: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

种属反应性: 人(Human), 食蟹猴(Cynomolgus monkey)

亚型: Human IgG4SP

宿主种属: 人(Human)

偶联: Unconjugated

CAS号: 1610943-06-0

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Evolocumab(anti-PCSK9)

规格或纯度 :

≥95%(SDS-PAGE&SEC-HPLC)
见COA

应用:

Animal Model
ELISA
Flow Cytometry
Functional Assay

关联靶标: PCSK9

简短描述: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

种属反应性: 人(Human), 小鼠(Mouse), 食蟹猴(Cynomolgus monkey)

亚型: Human IgG2

宿主种属: 人(Human)

偶联: Unconjugated

CAS号: 1256937-27-5 Compound CID : 168010177

IUPAC Name: 2-butylimino-3-[1-(4-fluorophenyl)ethyl]-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazolidin-4-one;2-(cyclopropylmethylimino)-3-[1-(4-fluorophenyl)ethyl]-5-[[3-methoxy-4-(4-methylimSee more

SMILES: CCCCN=C1NC(=CC2=CC(=C(C=C2)N3C=C(N=C3)C)OC)C(=O)N1C(C)C4=CC=C(C=C4)F.CCN=C1NC(=CC2=CC(=C(C=C2)N3C=C(N=C3)C)OC)C(=O)N1C(C)C4=CC=C(C=C4)F.CC1=CN(C=N1)C2=C(C=C(C=C2)C=C3C(=O)N(C(=NCCCO)N3)C(C)C4=CC=C(C=CSee more

InChIKey: PUHBRGRYFZDQIV-UHFFFAOYSA-N

InChI: 1S/C27H28FN5O2.C27H30FN5O2.C26H28FN5O3.C25H26FN5O2.C24H23FN4O3/c1-17-15-32(16-30-17)24-11-6-20(13-25(24)35-3)12-23-26(34)33(27(31-23)29-14-19-4-5-19)18(2)21-7-9-22(28)10-8-21;1-5-6-13-29-27-31-23(26(3See more

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