抗体类配体 - 小分子和化合物库

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Alirocumab (anti-PCSK9)
- ≥95%
- 75mg/ml in buffer
关联靶标: PCSK9
CAS号 : 1245916-14-6

SMILES: C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChIKey: CATWCRUATKKAAQ-UHFFFAOYSA-N

InChI: InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
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阿特珠单抗（抗PD-L1）
- ≥95%
- 见COA
- Flow Cytometry
关联靶标: CD274
CAS号 : 1380723-44-3 Compound CID : 168009942

SMILES: CC.CCCC(=NC(CC=C)C1=CC(=C(C=C1)N)S)C=C(C(=O)N(CCC(C)CC)C(C)CC)N.CC=CC(=CC)C(=O)C
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Durvalumab (anti-PD-L1)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: CD274
CAS号 : 1428935-60-7
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Avelumab (anti-PD-L1)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: CD274
CAS号 : 1537032-82-8 Compound CID : 168266339

IUPAC Name: 4-O-[2-(tert-butylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(cyclohexylmethylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(cyclohexylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(2,2-dimethylpropylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(ethylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(methanesulfonamido)-2-phenylethyl] 1-O-methyl but-2-enedioate;1-O-methyl 4-O-[2-(2-methylpropylsulfonylamino)-2-phenylethyl] but-2-enedioate;1-O-methyl 4-O-[2-phenyl-2-(propan-2-ylsulfonylamino)ethyl] but-2-enedioate

SMILES: CCS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)CS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)S(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)(C)CS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)(C)S(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)C.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)CC2CCCCC2.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)C2CCCCC2

InChIKey: YRKYEQYAGDIKGE-UHFFFAOYSA-N

InChI: InChI=1S/C20H27NO6S.C19H25NO6S.C18H25NO6S.2C17H23NO6S.C16H21NO6S.C15H19NO6S.C14H17NO6S/c1-26-19(22)12-13-20(23)27-14-18(17-10-6-3-7-11-17)21-28(24,25)15-16-8-4-2-5-9-16;1-25-18(21)12-13-19(22)26-14-17(15-8-4-2-5-9-15)20-27(23,24)16-10-6-3-7-11-16;1-18(2,3)13-26(22,23)19-15(14-8-6-5-7-9-14)12-25-17(21)11-10-16(20)24-4;1-17(2,3)25(21,22)18-14(13-8-6-5-7-9-13)12-24-16(20)11-10-15(19)23-4;1-13(2)12-25(21,22)18-15(14-7-5-4-6-8-14)11-24-17(20)10-9-16(19)23-3;1-12(2)24(20,21)17-14(13-7-5-4-6-8-13)11-23-16(19)10-9-15(18)22-3;1-3-23(19,20)16-13(12-7-5-4-6-8-12)11-22-15(18)10-9-14(17)21-2;1-20-13(16)8-9-14(17)21-10-12(15-22(2,18)19)11-6-4-3-5-7-11/h3,6-7,10-13,16,18,21H,2,4-5,8-9,14-15H2,1H3;2,4-5,8-9,12-13,16-17,20H,3,6-7,10-11,14H2,1H3;5-11,15,19H,12-13H2,1-4H3;5-11,14,18H,12H2,1-4H3;4-10,13,15,18H,11-12H2,1-3H3;4-10,12,14,17H,11H2,1-3H3;4-10,13,16H,3,11H2,1-2H3;3-9,12,15H,10H2,1-2H3
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Envafolimab (anti-PD-L1)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: CD274
CAS号 : 2102192-68-5
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Evolocumab(anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 1256937-27-5 Compound CID : 168010177

IUPAC Name: 2-butylimino-3-[1-(4-fluorophenyl)ethyl]-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazolidin-4-one;2-(cyclopropylmethylimino)-3-[1-(4-fluorophenyl)ethyl]-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazolidin-4-one;2-ethylimino-3-[1-(4-fluorophenyl)ethyl]-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazolidin-4-one;3-[1-(4-fluorophenyl)ethyl]-2-(3-hydroxypropylimino)-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazolidin-4-one;3-[1-(4-fluorophenyl)ethyl]-2-methoxy-5-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]imidazol-4-one

SMILES: CCCCN=C1NC(=CC2=CC(=C(C=C2)N3C=C(N=C3)C)OC)C(=O)N1C(C)C4=CC=C(C=C4)F.CCN=C1NC(=CC2=CC(=C(C=C2)N3C=C(N=C3)C)OC)C(=O)N1C(C)C4=CC=C(C=C4)F.CC1=CN(C=N1)C2=C(C=C(C=C2)C=C3C(=O)N(C(=NCCCO)N3)C(C)C4=CC=C(C=C4)F)OC.CC1=CN(C=N1)C2=C(C=C(C=C2)C=C3C(=O)N(C(=NCC4CC4)N3)C(C)C5=CC=C(C=C5)F)OC.CC1=CN(C=N1)C2=C(C=C(C=C2)C=C3C(=O)N(C(=N3)OC)C(C)C4=CC=C(C=C4)F)OC

InChIKey: PUHBRGRYFZDQIV-UHFFFAOYSA-N

InChI: InChI=1S/C27H28FN5O2.C27H30FN5O2.C26H28FN5O3.C25H26FN5O2.C24H23FN4O3/c1-17-15-32(16-30-17)24-11-6-20(13-25(24)35-3)12-23-26(34)33(27(31-23)29-14-19-4-5-19)18(2)21-7-9-22(28)10-8-21;1-5-6-13-29-27-31-23(26(34)33(27)19(3)21-8-10-22(28)11-9-21)14-20-7-12-24(25(15-20)35-4)32-16-18(2)30-17-32;1-17-15-31(16-29-17)23-10-5-19(14-24(23)35-3)13-22-25(34)32(26(30-22)28-11-4-12-33)18(2)20-6-8-21(27)9-7-20;1-5-27-25-29-21(24(32)31(25)17(3)19-7-9-20(26)10-8-19)12-18-6-11-22(23(13-18)33-4)30-14-16(2)28-15-30;1-15-13-28(14-26-15)21-10-5-17(12-22(21)31-3)11-20-23(30)29(24(27-20)32-4)16(2)18-6-8-19(25)9-7-18/h6-13,15-16,18-19H,4-5,14H2,1-3H3,(H,29,31);7-12,14-17,19H,5-6,13H2,1-4H3,(H,29,31);5-10,13-16,18,33H,4,11-12H2,1-3H3,(H,28,30);6-15,17H,5H2,1-4H3,(H,27,29);5-14,16H,1-4H3
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Alirocumab (anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 1245916-14-6

SMILES: C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChIKey: CATWCRUATKKAAQ-UHFFFAOYSA-N

InChI: InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
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Tafolecimab (anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 2225109-03-3
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Sugemalimab (anti-PD-L1)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: CD274
CAS号 : 2256084-03-2
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Bococizumab (anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 1407495-02-6
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Ralpancizumab (anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 1407495-04-8
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Frovocimab (anti-PCSK9)
- ≥95%(SDS-PAGE&SEC-HPLC)
- 见COA
- Animal Model
- ELISA
- Flow Cytometry
- Functional Assay
关联靶标: PCSK9
CAS号 : 1643672-70-1
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