基本信息

产品名称	Recombinant CD19 Antibody (AF555)
别名	CD19抗体 \| CD19单抗
英文别名	B-lymphocyte antigen CD19 \| B-lymphocyte surface antigen B4 \| CD19 antigen \| CD19 molecule \| CD19 \| CVID3 \| Differentiation antigen CD19 \| Leu-12 \| MGC12802 \| T-cell surface antigen Leu-12 \| Antibody deficiency due to defect in CD19 antibody \| Antibody de
规格或纯度	已验证, ExactAb™, 5 μL/test
生化机理	Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes (PubMed:29523808). Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:1373518, PubMed:16672701, PubMed:2463100). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores (PubMed:12387743, PubMed:16672701, PubMed:9317126, PubMed:9382888). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:9317126). Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:1373518, PubMed:2463100). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:12387743, PubMed:16672701, PubMed:9317126).
宿主种属	小鼠(Mouse)
特异性	Intact normal human B cell cells
种属反应性	人(Human)
阳性对照	Flow: Human peripheral blood lymphocytes
偶联	AF555
Excitation(nm)	Green Laser(532nm)
Emission(nm)	568nm
Ex/Em(nm)	Ex:553nm;Em:568nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冻结
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

图片

Flow Cytometry: Recombinant CD19 Antibody (AF555) (Ab213305)

Recombinant CD19 Antibody (AF555) (Ab213305) - Flow Cytometry
Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD19 Antibody (AF555) (Ab213305) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF555) (Ab190246).

Flow Cytometry: Recombinant CD19 Antibody (AF555) (Ab213305)

Recombinant CD19 Antibody (AF555) (Ab213305) - Flow Cytometry
Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD19 Antibody (AF555) (Ab213305) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF555) (Ab190246). Black - Unlabelled control, cells without incubation with primary antibody.

关联靶点（人）

CD19 Tclin B淋巴细胞抗原CD19(B-lymphocyte antigen CD19) (0 活性数据)

点击查看靶蛋白信息： CD19

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

安全和危险性（GHS）

SDS英文版

质量标准

质量标准

应用

应用名称	稀释比例
Flow Cytometry	5μl/test For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.