| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab191796-10μg |
10μg |
现货  |
| |
| Ab191796-25μg |
25μg |
现货 |
| |
| Ab191796-100μg |
100μg |
现货 |
|
| 产品名称 | SIRP alpha/CD172a Rat mAb (AF700) |
|---|---|
| 别名 | 信号调节蛋白α(SIRPa)抗体 | SIRP alpha/CD172a抗体 | SIRP alpha/CD172a抗体-AF700 | SIRP alpha/CD172a 大鼠单克隆抗体 (AF700) | SIRP alpha/CD172a 大鼠单抗 (AF700) |
| 英文别名 | Bit | SIRP | SHP-1 | Ptpns1 | Idd13.2 | BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs | Brain Ig-like molecule with tyrosine-based activation motifs | CD172 antigen-like family member A | CD172a antigen | CD172a | Inhibitory |
| 规格或纯度 | ExactAb™, 已验证, Ex:696nm, Em:719nm, 0.5 mg/mL |
| 生化机理 | CD47 的免疫球蛋白样细胞表面受体。作为对接蛋白，诱导 PTPN6、PTPN11 和其他结合伙伴从细胞膜转位到质膜。支持小脑神经元的粘附、神经元突起和胶质细胞的附着。可能在突触发生过程中的细胞内信号传导和突触功能中发挥关键作用（相似）。参与细胞粘附、生长因子或胰岛素诱导的受体酪氨酸激酶偶联细胞反应的负向调节。介导吞噬、肥大细胞活化和树突状细胞活化的负向调节。与 CD47 结合可阻止未成熟树突状细胞的成熟，并抑制成熟树突状细胞产生细胞因子。 |
| 宿主种属 | 大鼠(Rat) |
| 特异性 | SIRP alpha/CD172a |
| 种属反应性 | 小鼠(Mouse) |
| 免疫原 | Mouse brain membrane protein |
| 阳性对照 | Flow: C57BL/6 mouse bone marrow cells. |
| 偶联 | AF700 |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 719nm |
| Ex/Em(nm) | Ex:696nm;Em:719nm |
| 克隆类型 | 单克隆抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Rat IgG1 |
| 轻链亚型 | kappa |
| 纯化方法 | Protein A purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300. |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 0.5 mg/mL |
| 储存温度 | 2-8°C储存,避光,禁止冻结 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 未稀释的抗体溶液应保存在 2°C 至 8°C 之间，避免长时间暴露在光线下。切勿冷冻。 |
| 分子类型 | 抗体 |
SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (right panel) compared to an isotype control (left panel). Cells were stained with SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) at 0.2μg/test for 1 hour at 4°C. Left panel - Rat IgG (AF700) (Ab190242).
SIRP alpha/SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (red) compared to an isotype control (blue). Cells were stained with SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) at 0.2μg/test for 1 hour at 4°C. Blue - Rat IgG (AF700) (Ab190242). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | ≤0.1 μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.1 μg per million cells in 100 µL staining volume. |
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1012310 |
分析证书 | 24-10-17 | Ab191796 |
| ZJ24F1012309 |
分析证书 | 24-10-17 | Ab191796 |
| ZJ24F1012308 |
分析证书 | 24-10-17 | Ab191796 |
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