尿酸酶 来源于产朊假丝酵母

功能和特点
有货

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
U128546-100UN
100U 现货 Stock Image

基本描述

产品名称 尿酸酶 来源于产朊假丝酵母
别名 尿酸酶
英文别名 FT-0772402 | Uricase from Bacillus fastidiosus, lyophilized, ~9 U/mg | Uricase from Candida sp., recombinant, expressed in E. coli, lyophilized powder, >=2 units/mg solid | VPXDHZMLJOJKOX-UHFFFAOYSA-N | Uricase from Arthrobacter globiformis, lyophilized p
规格或纯度 EnzymoPure™, ≥2 units/mg dry weight
生化机理 适用于在临床分析中测定尿酸。
产品介绍

Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.Oxidizes uric acid

Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Oxidizes uric acid

产品规格参数

浓度 ≥2 units/mg dry weight
储存温度 -20°C储存
运输条件 超低温冰袋运输
CAS编号和信息 9002-12-4
酶学委员会编号 1.7.3.3
单位定义 One Unit oxidizes one micromole of uric acid per minute
分子类型

安全和危险性(GHS)

象形图 GHS08
信号词 Danger
危险声明

H334: 吸入可能引起过敏或哮喘病症状或呼吸困难

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P501: 将内容物/容器处理到。。。

P284: 如果通风不良,请佩戴呼吸防护装置。

P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。

P342+P316: 如果出现呼吸道症状:立即寻求急救。

WGK Germany 3
RTECS YU7100000
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

质量标准

Enzymatic Activity(Dry Basis) ≥2(units/mg)
Appearance(U128546) lyophilized powder

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到5个结果

批号(Lot Number) 证书类型 日期 货号
D2502559 分析证书 25-03-18 U128546
D2429469 分析证书 24-03-14 U128546
D2429470 分析证书 24-03-14 U128546
I2305219 分析证书 23-08-15 U128546
D2230082 分析证书 22-03-03 U128546

此产品的引用文献

1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe.  (2022)  Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification.  MICROCHIMICA ACTA,  189  (11): (1-9).  [PMID:36318325] [10.1007/s00604-022-05535-8]
2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin.  (2021)  Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase.  ANALYTICAL CHEMISTRY,  93  (45): (15183–15191).  [PMID:34743510] [10.1021/acs.analchem.1c03842]
3. Guojun Cao, Can Wu, Yong Tang, Chidan Wan.  (2019)  Ultrasmall HKUST-1 nanoparticles decorated graphite nanosheets for highly sensitive electrochemical sensing of DNA damage biomarker 8-hydroxy-2’-deoxyguanosine.  ANALYTICA CHIMICA ACTA,  1058  (80).  [PMID:30851856] [10.1016/j.aca.2019.01.031]
4. Aijin Fang, Qiongqiong Wu, Qiujun Lu, Hongyu Chen, Haitao Li, Meiling Liu, Youyu Zhang, Shouzhuo Yao.  (2016)  Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.  BIOSENSORS & BIOELECTRONICS,  86  (664).  [PMID:27471157] [10.1016/j.bios.2016.07.055]

参考文献

1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe.  (2022)  Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification.  MICROCHIMICA ACTA,  189  (11): (1-9).  [PMID:36318325] [10.1007/s00604-022-05535-8]
2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin.  (2021)  Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase.  ANALYTICAL CHEMISTRY,  93  (45): (15183–15191).  [PMID:34743510] [10.1021/acs.analchem.1c03842]
3. Guojun Cao, Can Wu, Yong Tang, Chidan Wan.  (2019)  Ultrasmall HKUST-1 nanoparticles decorated graphite nanosheets for highly sensitive electrochemical sensing of DNA damage biomarker 8-hydroxy-2’-deoxyguanosine.  ANALYTICA CHIMICA ACTA,  1058  (80).  [PMID:30851856] [10.1016/j.aca.2019.01.031]
4. Aijin Fang, Qiongqiong Wu, Qiujun Lu, Hongyu Chen, Haitao Li, Meiling Liu, Youyu Zhang, Shouzhuo Yao.  (2016)  Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.  BIOSENSORS & BIOELECTRONICS,  86  (664).  [PMID:27471157] [10.1016/j.bios.2016.07.055]

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