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奎诺二甲基丙烯酸酯

抗氧化剂维生素E衍生物
98篇引用文献
  • ≥98%
  • white
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
T137260-250mg
 250mg 现货 Stock Image
T137260-1g
 1g 现货 Stock Image
T137260-5g
 5g 现货 Stock Image
T137260-25g
 25g 现货 Stock Image
大包装询价 收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
Apoptosis (1467) Ferroptosis (208) Heterocyclic Building Blocks (20) Immunology/Inflammation (1941) Metabolic Enzyme/Protease (4888) NF-κB (753) Reactive Oxygen Species (316) 六元杂环化合物 (1702) 氧化应激 (41)
main product photo

基本描述

别名 水溶性维生素E | 6-羟基-2,5,7,8-四甲基苯并二氢吡喃-2-甲酸,(±)-6-羟基-2,5,7,8-四甲基色满-2-羧酸
英文别名 trolox | TROLOX C | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid | 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
规格或纯度 ≥98%, white
英文名称 (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
生化机理 抗氧化剂维生素E衍生物。表现出脂质过氧化，DPPH°清除和HO°清除活性。经常用作抗氧化剂标准。具有细胞渗透性和水溶性。
储存温度 2-8°C储存,充氩
运输条件 冰袋运输
备注 外观是白色 。如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。
产品介绍

(±)-6-羟基-2,5,7,8-四甲基色满-2-羧酸（Trolox）已用于6-羟基-2,5,7,8-四甲基色满-2-羧酸等效抗氧化检测（TEAC）以确定不同水果物种的总抗氧化能力。


关联靶点（人）

PTGS1 Tclin 前列腺素 G/H 合酶 1(Prostaglandin G/H synthase 1) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PTGS2 Tclin 前列腺素 G/H 合酶 2(Prostaglandin G/H synthase 2) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TYR Tclin Tyrosinase (717 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ALB Tchem Serum albumin (2651 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AKR1A1 Tchem Aldehyde reductase (91 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Caco-2 (12174 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MRC5 (9203 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NHDF (1164 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
U373 MG (658 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
T47D (39041 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HBL-100 (746 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HEK293 (82097 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
WiDr (1835 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HepG2 (196354 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Jurkat (10389 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BT-549 (31254 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SW1573 (1008 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DHRS9 Tbio Dehydrogenase/reductase SDR family member 9 (11 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ARNT Tbio Aryl hydrocarbon receptor nuclear translocator (25 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Liver (3974 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BCHE Tclin Cholinesterases; ACHE & BCHE (1222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ARPE-19 (321 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HMEC-1 (426 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

ampC Beta-lactamase AmpC (62480 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Fdft1 Squalene synthetase (34 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Carboxylesterase (379 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human alphaherpesvirus 2 (4932 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human respirovirus 3 (1674 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bos taurus (956 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vaccinia virus (4609 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human alphaherpesvirus 1 (11089 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sindbis virus (1599 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vesicular stomatitis virus (4460 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Influenza A virus (11224 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Punta Toro virus (1491 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Coxsackievirus B4 (2249 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Respiratory syncytial virus (3434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NG108-15 (132 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
C6 (2371 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HT-22 (3261 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
LOX1.1 Seed lipoxygenase-1 (463 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mixed cortical cells (27 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rotifers (49 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Feline coronavirus (624 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mammalian orthoreovirus 1 (1523 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Brain (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Kidney (1278 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Liver microsome (341 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NRK-52E (51 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

分子类型 小分子
IUPAC Name 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
INCHI InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChi Key GLEVLJDDWXEYCO-UHFFFAOYSA-N
Canonical SMILES CC1=C(C2=C(CCC(O2)(C)C(=O)O)C(=C1O)C)C
Isomeric SMILES CC1=C(C2=C(CCC(O2)(C)C(=O)O)C(=C1O)C)C
WGK Germany 2
RTECS DJ2273000
PubChem CID 40634
分子量 250.29
Beilstein号 1384050
Reaxy-Rn 5052542

化学和物理性质

溶解性 Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly 0.5mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml)
敏感性 对空气敏感；易吸湿
熔点 187-189 °C
分子量 250.290 g/mol
XLogP3 2.800
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 250.121 Da
单同位素质量Monoisotopic Mass 250.121 Da
拓扑极表面积Topological Polar Surface Area 66.800 Ų
重原子数Heavy Atom Count 18
形式电荷Formal Charge 0
复杂度Complexity 343.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 1
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 2
RTECS DJ2273000
Reaxy-Rn 5052542
个人防护装备 dust mask type N95 (US)， Eyeshields， Gloves

 SDS英文版

质量标准

Purity(HPLC) 98-100（%）
Purity(Neutralization titration) 97.5-102.5（%）
Melting point 187-194（℃）
Appearance（T137260) white to off-white,yellow or green powder or chunk
Proton NMR spectrum Conforms to Structure

 质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到48个结果

批号(Lot Number) 证书类型 日期 货号
D2508668 分析证书 25-04-01 T137260
D2508710 分析证书 25-04-01 T137260
D2508664 分析证书 25-04-01 T137260
D2508665 分析证书 25-04-01 T137260
D2511694 分析证书 25-04-01 T137260
C2510326 分析证书 25-03-04 T137260
C2510327 分析证书 25-03-04 T137260
C2510328 分析证书 25-03-04 T137260
C2510329 分析证书 25-03-04 T137260
F2314816 分析证书 25-03-03 T137260
F2314829 分析证书 25-03-03 T137260
F2314830 分析证书 25-03-03 T137260
F2314916 分析证书 25-03-03 T137260
F2314918 分析证书 25-03-03 T137260
E2430438 分析证书 24-05-20 T137260
E2431269 分析证书 24-05-20 T137260
J2325693 分析证书 23-10-17 T137260
J2325694 分析证书 23-10-17 T137260
I2327108 分析证书 23-09-25 T137260
I2327109 分析证书 23-09-25 T137260
F23161130 分析证书 23-06-21 T137260
F23161139 分析证书 23-06-21 T137260
F23161196 分析证书 23-06-21 T137260
F23161137 分析证书 23-06-20 T137260
F23161135 分析证书 23-06-20 T137260
F23161134 分析证书 23-06-20 T137260
F23161140 分析证书 23-06-20 T137260
E23081193 分析证书 23-04-13 T137260
E23081269 分析证书 23-04-13 T137260
E23081333 分析证书 23-04-13 T137260
E23081334 分析证书 23-04-13 T137260
B2310809 分析证书 23-01-14 T137260
B2310811 分析证书 23-01-14 T137260
B2310815 分析证书 23-01-14 T137260
B2124222 分析证书 22-12-08 T137260
H2219540 分析证书 22-08-11 T137260
H2219548 分析证书 22-08-11 T137260
J2021018 分析证书 22-08-10 T137260
J1811225 分析证书 22-08-05 T137260
G2226101 分析证书 22-07-28 T137260
G2207392 分析证书 22-06-15 T137260
I2130128 分析证书 21-09-15 T137260
F2229129 分析证书 21-09-15 T137260
J2228156 分析证书 21-09-15 T137260
I2130124 分析证书 21-09-15 T137260
I2130125 分析证书 21-09-15 T137260
I2130126 分析证书 21-09-15 T137260
I2130127 分析证书 21-09-15 T137260

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