SC83288

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货号 (SKU)	包装规格	是否现货	价格	数量
S613482-5mg	5mg	期货
S613482-25mg	25mg	期货

基本描述

规格或纯度	Moligand™
英文名称	SC83288

Plasmodium falciparum (966862 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

IUPAC Name	methyl 4-[3-[[4-[(4-sulfamoylphenyl)methylsulfamoyl]phenyl]carbamoylamino]benzenecarboximidoyl]piperazine-1-carboxylate
INCHI	InChI=1S/C27H31N7O7S2/c1-41-27(36)34-15-13-33(14-16-34)25(28)20-3-2-4-22(17-20)32-26(35)31-21-7-11-24(12-8-21)43(39,40)30-18-19-5-9-23(10-6-19)42(29,37)38/h2-12,17,28,30H,13-16,18H2,1H3,(H2,29,37,38)(H2,31,32,35)
InChi Key	UJKWTQWUYKHLGQ-UHFFFAOYSA-N
Canonical SMILES	COC(=O)N1CCN(CC1)C(=N)c1cccc(c1)NC(=O)Nc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(=O)(=O)N
Isomeric SMILES	COC(=O)N1CCN(CC1)C(=N)C2=CC(=CC=C2)NC(=O)NC3=CC=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)S(=O)(=O)N
PubChem CID	57496162

C of A & Other Certificates(BSE/TSE, COO):

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1. Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A et al.. (2017) SC83288 is a clinical development candidate for the treatment of severe malaria.. Nat Commun, 8 (14193). [PMID:28139658]
2. Duffey M, Sanchez CP, Lanzer M. (2018) Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum.. Malar J, 17 (1): (121). [PMID:29558913]