| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp183746-10μg |
10μg |
现货  |
| |
| rp183746-50μg |
50μg |
现货 |
| |
| rp183746-100μg |
100μg |
现货 |
| |
| rp183746-1mg |
1mg |
期货 |
|
| 产品名称 | Recombinant Human PARP-1 Protein |
|---|---|
| 别名 | 重组人PARP-1蛋白 |
| 规格或纯度 | Carrier Free, ≥95%(SDS-PAGE) |
| 产品介绍 |
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. |
| 生物活性 | Testing in progress |
| 内毒素水平 | <1.0 EU/μg |
| 表达系统 | E. coli |
| 种属 | 人(Human) |
| 氨基酸 | 373-686 aa |
| 序列 | MHHHHHHTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAM |
| 蛋白标签 | N-His |
| 无载体 | Yes |
| 无动物源 | No |
| Accession # | P09874 |
| 来源 | 重组表达 |
| 预测分子量 | 35.6 kDa |
| SDS-PAGE | 34.9 kDa, under reducing conditions; 34.9 kDa, under non-reducing conditions |
Recombinant Human PARP-1 Protein (rp183746) - SDS-PAGE
3 μg/lane of Recombinant Human PARP-1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 34.9 kDa.
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from PBS, pH 7.4 |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。 |
| 分子类型 | 蛋白质 |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0809128 |
分析证书 | 24-08-08 | rp183746 |
| ZJ24F0809127 |
分析证书 | 24-08-08 | rp183746 |
| ZJ24F0809126 |
分析证书 | 24-08-08 | rp183746 |
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