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Recombinant Human Gremlin 1 Protein
- 种属: 人(Human)
- Accession #: O60565
- 表达系统: E. coli
- 蛋白标签: N-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Gremlin 1 is an inhibitor in the TGF-beta signaling pathway. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. Measured by its binding ability in a functional ELISA. Immobilized Human BMP-7 at 2 μg/mL can bind Recombinant Human Gremlin 1 Protein (rp146650) with the EC50 of 0.10 μg/mL.
