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信号通路蛋白
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Recombinant Human PCNA Protein
- 种属: 人(Human)
- Accession #: P12004
- 表达系统: E. coli
- 蛋白标签: N-His
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Recombinant Human DKK3 Protein
- 种属: 人(Human)
- Accession #: Q9UBP4
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to inhibit proliferation of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 3-12 µg/mL.
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Recombinant Human Clusterin Protein
- 种属: 人(Human)
- Accession #: P10909-1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to induce clustering of Caki‑2 human clear cell carcinoma epithelial cells.
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Recombinant Human Osteopontin Protein
- 种属: 人(Human)
- Accession #: P10451.1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: 1、Measured by the ability of the immobilized protein to support the adhesion of HEK293 human embryonic kidney cells.Recombinant Human Osteopontin/OPN coated plate, cell adhesion is enhanced in a dose-dependent manner after 1 hour incubation at 37 °C. The ED₅₀ for this effect is 0.2-0.8 µg/mL. 2、Measured by its binding ability in a functional ELISA. When Recombinant Human Osteopontin (rp149597) is immobilized at 4 µg/mL, biotinylated Recombinant Human Mesothelin (rp176301) binds with an ED50 of 40.2 ng/mL.
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Recombinant Human Parathyroid Hormone Protein
- 种属: 人(Human)
- Accession #: P01270
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg.
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Recombinant Human DLL1 Protein
- 种属: 人(Human)
- Accession #: O00548
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Measured by its ability to bind human NOTCH1 in a functional ELISA. 2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL.
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Recombinant Human FGL1 Protein
- 种属: 人(Human)
- Accession #: Q08830
- 表达系统: HEK293
- 蛋白标签: C-hFc
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Immobilized Recombinant Human LAG-3 Protein at 1 μg/mL can bind biotinylated Recombinant Human FGL1 Protein (rp146027).2. Loaded Human LAG-3 Protein on AMC Biosensor, can bind Recombinant Human FGL1 Protein (rp146027) with an affinity constant of 56.8 nM as determined in BLI assay.
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Recombinant Human SFRP4 Protein
- 种属: 人(Human)
- Accession #: Q6FHJ7
- 表达系统: CHO
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured by its ability to inhibit Wnt3a-induced alkaline phosphatase production by C3H10T 1/2 2A6 mouse embryonal fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL in the presence of 20 ng/mL of Wnt3a.
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Recombinant Human Gremlin 1 Protein
- 种属: 人(Human)
- Accession #: O60565
- 表达系统: E. coli
- 蛋白标签: N-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Gremlin 1 is an inhibitor in the TGF-beta signaling pathway. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. Measured by its binding ability in a functional ELISA. Immobilized Human BMP-7 at 2 μg/mL can bind Recombinant Human Gremlin 1 Protein (rp146650) with the EC50 of 0.10 μg/mL.
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Recombinant Human FGF8 Protein
- 种属: 人(Human)
- Accession #: P55075
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.8-3.3 μg/mL.
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Recombinant Human BMP3 Protein
- 种属: 人(Human)
- Accession #: P12645.1
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit BMP-2-induced activity in murine MC3T3‑E1 cells.
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Recombinant Human Amphiregulin Protein
- 种属: 人(Human)
- Accession #: P15514
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 5-10 ng/ml.
