功能和特点
有货

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
R755846-20μg
20μg 期货 Stock Image

基本描述

产品名称
规格或纯度 无动物源, 重组, ≥98%(SDS-PAGE&HPLC), expressed in E. coli
生化机理 正常 T 细胞表达和分泌的活化调控(RANTES)是一种趋化因子,可吸引单核细胞、树突状细胞(DC)、记忆 T 细胞(CD4+/CD45RO)、嗜碱性粒细胞和嗜酸性粒细胞。 1 RANTES 可通过阻断 CCR5 受体抑制 R5 株 HIV-1 的作用。RANTES 基因的 In1.1C 变异与 HIV-1 感染的易感性和疾病进展有关。因此,它可以作为一种有效的生物标志物来确定 HIV-1 感染的预后。
产品介绍

RANTES human has been used in following studies:In transmigration experiments to determine whether LFA-1 cross-linking could affect peripheral blood T lymphocytes (PBTL) migration in response to the chemokine RANTES.Luminol-dependent chemiluminescence assay to determine the effect of RANTES on reactive oxygen species (ROS) production by eosinophils.应用:

Regulated on activation, normal T cell expressed and secreted (RANTES) also known as C-C motif chemokine ligand 5 (CCL5) is encoded by the gene mapped to human chromosome 17. RANTES belongs to intercrine or chemokine family of proinflammatory basic polypeptides and is expressed by various hematopoietic and non-hematopoietic cell types involved in homing and migration of effector and memory T cells during acute infections. Recombinant human RANTES is a 7.8kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Regulated on activation, normal T cell expressed and secreted (RANTES) also known as C-C motif chemokine ligand 5 (CCL5) is encoded by the gene mapped to human chromosome 17. RANTES belongs to intercrine or chemokine family of proinflammatory basic polypeptides and is expressed by various hematopoietic and non-hematopoietic cell types involved in homing and migration of effector and memory T cells during acute infections. Recombinant human RANTES is a 7.8kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Application:
RANTES human has been used in following studies:
  • In transmigration experiments to determine whether LFA-1 cross-linking could affect peripheral blood T lymphocytes (PBTL) migration in response to the chemokine RANTES.
  • Luminol-dependent chemiluminescence assay to determine the effect of RANTES on reactive oxygen species (ROS) production by eosinophils.

产品规格参数

物理形态 固体
浓度 expressed in E. coli
储存温度 -20°C储存
运输条件 超低温冰袋运输

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