基本描述

产品名称

重组人血清白蛋白OsrHSA

别名

rHSA, 白蛋白人, 重组人血白蛋白

英文别名

规格或纯度

用于细胞培养, ≥99%

产品介绍

人血清白蛋白（Human Serum Albumin，HSA）作为人血浆中含量最丰富的蛋白，是激素、脂类等物质的转运载体，其主要生理功能是调节血浆pH值和维持血浆渗透压。

OsrHSA（Recombinant Human Serum Albumin from Oryza sativa）是利用水稻胚乳细胞表达平台（OryzHiExp）和纯化平台（OryzPur）研发的重组人血清白蛋白，不含有动物源成分，可杜绝血液源的病毒感染风险。与胎牛血清（FBS）、血浆来源白蛋白（pHSA）和牛血清白蛋白（BSA）相比，OsrHSA具有更高的纯度，更好的批次稳定性，可以用于各类研究，包括生物制药、细胞治疗、基因治疗的细胞培养等，可替换血清，促进细胞生长。同时，OsrHSA也被广泛用于生物医药生产中作为药物载体，疫苗保护剂、细胞冻存保护剂和医疗器械包埋剂等。

产品参数
货号：R283928
规格：99%，细胞培养级
内毒素：<0.125EU/mg
pH： 6.0～8.0
HCP：——
HCD：——
铝残留量：——
硫酸铵残留量：——
GMP：YES
DMF：——
CDE辅料备案：——；
推荐应用

细胞培养，血浆基质对照；封闭剂；酶保护剂；

说明

包装量指的是蛋白的总量，每瓶实际包含“蛋白+保护剂”

应用领域

生物制药、人用疫苗、细胞培养、医疗器械、体外诊断、美容等。

注意事项

复溶：建议用PBS重溶OsrHSA冻干粉。溶解后的无菌OsrHSA在4℃可保存3-6个月。

开启后，请尽快使用，避免污染。

OsrHSA和天然人白pHSA理化性质比较

理化性质	pHSA	OsrHSA
氨基酸序列	一致
N-端氨基酸	DAHKSEV	DAHKSEV
C-端氨基酸	KLVAASQAALGL	KLVAASQAALGL
糖苷修饰	无
分子量 (MALDl)	66.554 (kDa)	66.550 ( a)
等电点 (pl)	4.8	4.8
药物结合活性	相近
热稳定性	熔点 65℃	熔点 65℃
酯酶活性	相同
晶体结构	相同

使用限制：

以上产品仅适于科研、实验室和生产使用，不能直接使用于人体。

As the most abundant protein in human plasma, human serum albumin (HSA) is the transporter of hormones, lipids and other substances. Its main physiological function is to regulate plasma pH and maintain plasma osmotic pressure.

Osrhsa (recombinant human serum albumin from Oryza sativa) is a recombinant human serum albumin developed by using rice endosperm cell expression platform (oryzhiexp) and purification platform (oryzpur). It does not contain animal derived ingredients and can eliminate the risk of blood derived virus infection. Compared with fetal bovine serum (FBS), plasma derived albumin (pHSA) and bovine serum albumin (BSA), osrhsa has higher purity and better batch stability. It can be used in various research fields, including biopharmaceutical, cell therapy and cell culture of gene therapy. It can replace serum and promote cell growth. At the same time, osrhsa is also widely used in biomedical production as drug carrier, vaccine protector, cell cryoprotectant and medical device embedding agent.

Application

Biopharmaceuticals, human vaccines, cell culture, medical devices, in vitro diagnosis, beauty, etc.

Matters needing attention

Re dissolving: it is suggested to re dissolve osrhsa lyophilized powder with PBS. The dissolved sterile osrhsa can be stored at 4 ℃ for 3-6 months.

After opening, please use it as soon as possible to avoid pollution.

Comparison of physical and chemical properties between OsrHSA and natural human white pHSA

physicochemical properties	pHSA	OsrHSA
amino acid sequence	agreement
N-terminal amino acids	DAHKSEV	DAHKSEV
C-terminal amino acids	KLVAASQAALGL	KLVAASQAALGL
Glycoside modification	nothing
molecular weight (MALDl)	66.554 (kDa)	66.550 ( a)
Isoelectric point (pl)	4.8	4.8
Drug binding activity	close
thermal stability	mp 65℃	mp 65℃
esterase activity	identical
crystal structure	identical

Restrictions on use:

The above products are only suitable for scientific research, laboratory and production use, and cannot be directly used in human body.

内毒素水平

<0.125 EU/mg

表达系统

种属

人(Human)

氨基酸

25-609 aa

蛋白标签

No tag

Accession #

P02768

关联靶点（人）

Homo sapiens (32628 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Rattus norvegicus (775804 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

产品规格参数

储存温度	2-8°C储存
运输条件	冰袋运输
CAS编号和信息	70024-90-7
分子类型	小分子

安全和危险性（GHS）

WGK Germany	3

SDS英文版

质量标准

Appearance(R283928)	white to light yellow powder
Purity(SDS-PAGE)	99-100（%）
Bacterial endotoxins	≤ 0.125（EU/mg）
Total protein content	90-100(%)

质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到16个结果

批号(Lot Number)	证书类型	日期	货号
K2429731	分析证书	24-10-31	R283928
K2429745	分析证书	24-10-31	R283928
E2415264	分析证书	24-04-22	R283928
E2415265	分析证书	24-04-22	R283928
E2415263	分析证书	24-04-22	R283928
C2408528	分析证书	24-02-29	R283928
L2318390	分析证书	23-12-13	R283928
L2318391	分析证书	23-12-13	R283928
L2318392	分析证书	23-12-13	R283928
K2309490	分析证书	23-11-03	R283928
K2309492	分析证书	23-11-03	R283928
K2212571	分析证书	22-09-21	R283928
B2321356	分析证书	22-09-21	R283928
F2309033	分析证书	22-09-21	R283928
I2322141	分析证书	22-09-21	R283928
K2212563	分析证书	22-09-21	R283928

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51. Long Zhao, Tao Wang, Qiang Wu, Yuan Liu, Zhoujiang Chen, Xiaohong Li. (2017) Fluorescent Strips of Electrospun Fibers for Ratiometric Sensing of Serum Heparin and Urine Trypsin. ACS Applied Materials & Interfaces, 9 (4): (3400–3410). [PMID:28067489] [10.1021/acsami.6b14118]
52. Sun Xiaotian, Hui Ni, Luo Xiliang. (2017) Reagentless and label-free voltammetric immunosensor for carcinoembryonic antigen based on polyaniline nanowires grown on porous conducting polymer composite. MICROCHIMICA ACTA, 184 (3): (889-896). [10.1007/s00604-016-2068-0]
53. Guixiang Wang, Rui Han, Xiaoli Su, Yinan Li, Guiyun Xu, Xiliang Luo. (2017) Zwitterionic peptide anchored to conducting polymer PEDOT for the development of antifouling and ultrasensitive electrochemical DNA sensor. BIOSENSORS & BIOELECTRONICS, 92 (396). [PMID:27829555] [10.1016/j.bios.2016.10.088]
54. Kong Lijun, Hu Jinxia, Qin Dan, Yan Peng. (2015) Interaction of Ifosfamide-Loaded Superparamagnetic Iron Oxide Nanoparticles with Human Serum Albumin—A Biophysical Study. Journal of Pharmaceutical Innovation, 10 (1): (13-20). [10.1007/s12247-014-9199-9]
55. Huo Jiansheng, Zheng Yuhui, Pang Shuting, Wang Qianming. (2013) Assembly of novel Tb3+/Eu3+ sensitized cellulose gels and their emission behaviors. CELLULOSE, 20 (2): (841-848). [10.1007/s10570-012-9854-6]

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重组人血清白蛋白OsrHSA

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溶液计算器

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