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白藜芦醇

环氧合酶抑制剂
141篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
R107315-1g
 1g 现货 Stock Image
R107315-5g
 5g 现货 Stock Image
R107315-10g
 10g 现货 Stock Image
R107315-25g
 25g 现货 Stock Image
R107315-100g
 100g 现货 Stock Image
R107315-500g
 500g 现货 Stock Image
大包装询价 收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
Anti-infection (2825) Antibiotic (625) Apoptosis (1467) Autophagy (555) Bacterial (717) Cell Cycle/DNA Damage (2603) Fungal (385) IKK (58) Keap1-Nrf2 (106) Mitophagy (30) NF-κB (753) Sirtuin (94) 化学预防剂 (37) 苯丙素类 (152) 表观遗传学 (1496)
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基本描述

别名 芪三酚 | 3,4',5-三羟基芪 | 3,4',5-三羟基-反式-二苯乙烯 | 5-[(1E)-2-(4-羟基苯基)乙烯基]-1,3-苯二酚 | (E)-5-[2-(4-羟苯基)-乙烯基]-1,3-苯二酚 | 反式-1,2-(3,4',5-三羟基二苯基)乙烯； 虎杖甙元
英文别名 Q369O8926L | CHEBI:27881 | CU-01000001503-3 | HMS1792H15 | NSC133100 | BPBio1_000479 | NCGC00344093-09 | RESVERATROL (MART.) | MLS000069735 | MLS001076538 | Stilbene, 2f | (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol | MLS002222231 | TaxusChinensisi
规格或纯度 Moligand™, ≥99%
英文名称 Resveratrol
生化机理 具有抗肿瘤，抗氧化剂，抗血小板，抗炎和抗真菌作用的植物雌激素。抑制细胞色素P450 1A1（IC50 =23μM），并对ERα和ERβ雌激素受体显示混合的激动剂/拮抗剂作用。通过细胞色素P450 1B1转化为抗癌药piceatannol。激活自噬。还激活前列腺癌相关成纤维细胞中的TRPA1。也是SIRT1激活剂。
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

白藜芦醇是一种在葡萄皮和其他植物中发现的酚类植物抗毒素。这种成分具有胞内抗氧化活性，可激活烟酰胺腺嘌呤二核苷酸(NAD+)依赖性组蛋白脱乙酰基酶1 (SIRT1)，参与线粒体生物发生、增强过氧化物酶体增殖物激活受体γ共激活因子-1a (PGC-1a)和FOXO（叉头框）活性。白藜芦醇的抗糖尿病、神经保护和抗脂肪形成作用可能是通过SIRT1的激活而介导的。白藜芦醇对单纯疱疹病毒-1 (HSV1)和HSV2具有抗病毒作用。此外，它还具有抗肿瘤和植物雌激素生物活性。目前确知白藜芦醇可通过介导几种生理事件，延长许多物种的寿命。
应用
COX-1 选择性抑制剂。
白藜芦醇已用于：
包封实验 
研究其对Ca2+/钙调蛋白依赖性蛋白激酶II的糖尿病诱导激活介导的视网膜神经元细胞死亡的神经保护作用 
用作体内荧光法评估葡萄叶stilbene含量的标准品

Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events.
Application
Resveratrol has been used:
in entrapment experiment 
to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II[2]
as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry
Selective inhibitor of COX−1.

关联靶点（人）

CYP1B1 Tchem 细胞色素 P450 1B1(Cytochrome P450 1B1) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CYP3A4 Tclin 细胞色素P450 3A4(Cytochrome P450 3A4) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
DPP4 Tclin 二肽基肽酶4(Dipeptidyl peptidase 4) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TRPA1 Tclin 瞬时受体电位阳离子通道亚家族A成员1(Transient receptor potential cation channel subfamily A member 1) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TTR Tclin 转甲状腺素蛋白(Transthyretin) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PTGS1 Tclin 前列腺素 G/H 合酶 1(Prostaglandin G/H synthase 1) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PTGS2 Tclin 前列腺素 G/H 合酶 2(Prostaglandin G/H synthase 2) (5 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA12 Tclin 碳酸酐酶12(Carbonic anhydrase 12) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA14 Tclin 碳酸酐酶14(Carbonic anhydrase 14) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA9 Tclin 碳酸酐酶9(Carbonic anhydrase 9) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
MAOA Tclin 胺氧化酶[含黄素]A(Amine oxidase [flavin-containing] A) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
NQO2 Tchem 核糖二氢烟酰胺脱氢酶[醌](Ribosyldihydronicotinamide dehydrogenase [quinone]) (9 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PPARG Tclin 过氧化物酶体增殖激活受体γ(Peroxisome proliferator-activated receptor gamma) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLA1 Tclin DNA polymerase alpha subunit (225 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP19A1 Tclin Cytochrome P450 19A1 (6099 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TYR Tclin Tyrosinase (717 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ampC Beta-lactamase AmpC (62480 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ca7 Carbonic anhydrase VII (3 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Fdft1 Squalene synthetase (34 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sigmar1 Sigma opioid receptor (160 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ttr Transthyretin (14 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hsd11b1 11-beta-hydroxysteroid dehydrogenase 1 (202 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cckar Cholecystokinin A receptor (90 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CTSL Cathepsin L (58 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PIK3CA PI3-kinase p110-alpha subunit (51 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pde4d Phosphodiesterase 4D (4 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DPP4 Dipeptidyl peptidase IV (11 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Abcb1b P-glycoprotein 1 (174 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA4 Carbonic anhydrase IV (1713 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac1 Histone deacetylase 1 (93 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Gaa Acidic alpha-glucosidase (551 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus sanguinis (314 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus pneumoniae (31063 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Campylobacter jejuni (634 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Helicobacter pylori (3113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Agrobacterium tumefaciens (620 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Enterobacter cloacae (7976 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vibrio cholerae (1211 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Micrococcus luteus (7463 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Neisseria gonorrhoeae (1461 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus mutans (2687 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Brevibacillus brevis (46 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bacillus subtilis (32866 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Clostridium botulinum (46 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Clostridioides difficile (2968 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Clostridium perfringens (1165 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Listeria monocytogenes (2626 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488189835
EC号 610-504-8
分子类型 小分子
IUPAC Name 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
INCHI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChi Key LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Canonical SMILES C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O
Isomeric SMILES C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O
WGK Germany 3
RTECS CZ8987000
关联CAS 501-36-0
PubChem CID 445154
NSC Number 327430
MeSH Entry Terms 3,4',5-stilbenetriol;3,4',5-Trihydroxystilbene;3,5,4'-trihydroxystilbene;cis Resveratrol;cis-resveratrol;resveratrol;Resveratrol 3 sulfate;Resveratrol, (Z)-;resveratrol-3-sulfate;SRT 501;SRT-501;SRT501;trans Resveratrol;trans Resveratrol 3 O sulfate;trans
分子量 228.24

化学和物理性质

溶解性 可溶于乙醇，丙酮
密度 1.359
敏感性 对空气敏感，对热敏感
熔点 267 °C
分子量 228.240 g/mol
XLogP3 3.100
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 228.079 Da
单同位素质量Monoisotopic Mass 228.079 Da
拓扑极表面积Topological Polar Surface Area 60.700 Ų
重原子数Heavy Atom Count 17
形式电荷Formal Charge 0
复杂度Complexity 246.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 1
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 1
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H319: 引起严重眼睛刺激
预防措施声明

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
WGK Germany 3
RTECS CZ8987000
Merck Index 8158
个人防护装备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves

 SDS英文版

质量标准

Appearance（R107315) White to Off-White Powder
Proton NMR spectrum Conforms to Structure
Purity(HPLC area) 99-100（%）
Solubility in Acetone，Colorless to Faint Yellow,Clear,50 mg/ml pass

 质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到40个结果

批号(Lot Number) 证书类型 日期 货号
B2511363 分析证书 25-01-07 R107315
B2511384 分析证书 25-01-07 R107315
B2511385 分析证书 25-01-07 R107315
B2511386 分析证书 25-01-07 R107315
B2511387 分析证书 25-01-07 R107315
K2428330 分析证书 24-11-05 R107315
K2421523 分析证书 24-11-05 R107315
K2421531 分析证书 24-11-05 R107315
K2421532 分析证书 24-11-05 R107315
K2421537 分析证书 24-11-05 R107315
H2414485 分析证书 24-08-03 R107315
H2414486 分析证书 24-08-03 R107315
H2414487 分析证书 24-08-03 R107315
H2414488 分析证书 24-08-03 R107315
H2414489 分析证书 24-08-03 R107315
A2510397 分析证书 24-07-01 R107315
F2312847 分析证书 23-05-30 R107315
F2312848 分析证书 23-05-30 R107315
F2312849 分析证书 23-05-30 R107315
F2312854 分析证书 23-05-30 R107315
F2312859 分析证书 23-05-30 R107315
B2423018 分析证书 23-05-30 R107315
D2416046 分析证书 23-05-30 R107315
E2513013 分析证书 23-05-30 R107315
A2305719 分析证书 22-11-21 R107315
A2305722 分析证书 22-11-21 R107315
A2305726 分析证书 22-11-21 R107315
A2305727 分析证书 22-11-21 R107315
A2305729 分析证书 22-11-21 R107315
A2305730 分析证书 22-11-21 R107315
A2305836 分析证书 22-11-21 R107315
A2305837 分析证书 22-11-21 R107315
A2305845 分析证书 22-11-21 R107315
J2325051 分析证书 22-11-21 R107315
B2215615 分析证书 22-01-07 R107315
B2215626 分析证书 22-01-07 R107315
B2215708 分析证书 22-01-07 R107315
B2215709 分析证书 22-01-07 R107315
B2215836 分析证书 22-01-07 R107315
G2315051 分析证书 22-01-07 R107315

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此产品的引用文献

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1. Song Yu, Lianpeng Zou, Jiawei Zhao, Yiping Zhu.  (2023)  Resveratrol alleviates fumonisin-induced intestinal cytotoxicity by modulating apoptosis, tight junction, and inflammation in IPEC-J2 porcine intestinal epithelial cells.  ENVIRONMENTAL TOXICOLOGY,  [PMID:37955343] [10.1002/tox.24033]
2. Yifan Ma, Yi Qian, Yuteng Chen, Xiaoxu Ruan, Xiaoya Peng, Yi Sun, Jue Zhang, Jingjing Luo, Songlin Zhou, Chao Deng.  (2023)  Resveratrol modulates the inflammatory response in hPDLSCs via the NRF2/HO-1 and NF-κB pathways and promotes osteogenic differentiation.  JOURNAL OF PERIODONTAL RESEARCH,  [PMID:37905727] [10.1111/jre.13200]
3. Dong Wu, Huihui Ming, Wei Wu, Wenjie Yu, Gaowei Zhang, Jinzhu Gu, Meng Cui, Xueyong Huang, Fangjian Ning, Liping Luo.  (2024)  In situ neutral desorption-extractive electrospray ionization mass spectrometry reveals red-blue light promoted the accumulation of amino acids and polyphenols in Anoectochilus roxburghii.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  125  (105761).  [10.1016/j.jfca.2023.105761]
4. Nayun Kim, Junhye Kwon, Ui Sup Shin, Joohee Jung.  (2023)  Stimulatory Anticancer Effect of Resveratrol Mediated by G Protein-Coupled Estrogen Receptor in Colorectal Cancer.  Biomolecules & Therapeutics,  31  (6): ( 655–660).  [PMID:37817377] [10.4062/biomolther.2023.072]
5. Yuan Gu, Yanjun Cai, Yige Kou, Erzhuo Cheng, Hanjie Bi, Min Hu, Songyao Wu, Yong Jiang, Jingxi Zhang, Qingting Wu, Yunyi Li, Bin Yang.  (2023)  Construction of multifunctional targeted nano-prodrugs based on PAMAM dendrimers for tumor therapy.  EUROPEAN POLYMER JOURNAL,  200  (112486).  [10.1016/j.eurpolymj.2023.112486]
6. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge.  (2023)  Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols.  Food and Bioprocess Technology,  (1-13).  [10.1007/s11947-023-03217-8]
7. Chen Wang, Ding Tang, Wei Xu, Yan Liu, Zhao-He Huang, Pang-Chui Shaw, Ren-Wang Jiang.  (2023)  Glycosylation of the polyphenols from Resina draconis by glycosyltransferase YjiC1.  NATURAL PRODUCT RESEARCH,  [PMID:35437081] [10.1080/14786419.2022.2066100]
8. Zhiyu Sun, Yongbin Zhou, Wenxu Zhu, You Yin.  (2023)  Assessment of the Fruit Chemical Characteristics and Antioxidant Activity of Different Mulberry Cultivars (Morus spp.) in Semi-Arid, Sandy Regions of China.  Foods,  12  (18): (3495).  [PMID:37761204] [10.3390/foods12183495]
9. Li Yanyan, Wang Hongling, Shi Haiming, Guo Qin, Zhang Yuquan, Shi Aimin, Jiang Yuanrong, Wang Qiang.  (2023)  Quantification of Resveratrol in Peanut Oils Using Stable Isotope Dilution Ultra-high Performance Liquid Chromatography-Mass Spectrometry.  Food Analytical Methods,  16  (11): (1673-1679).  [10.1007/s12161-023-02534-0]
10. Yao Ke, Mou Qianxue, Lou Xiaotong, Ye Meng, Zhao Bowen, Hu Yuanyuan, Luo Jing, Zhang Hong, Li Xing, Zhao Yin.  (2023)  Microglial SIRT1 activation attenuates synapse loss in retinal inner plexiform layer via mTORC1 inhibition.  Journal of Neuroinflammation,  20  (1): (1-18).  [PMID:37670386] [10.1186/s12974-023-02886-8]
11. Yajie Zhang, Changjiao Shang, Chaofan Sun, Lingling Wang.  (2024)  Simultaneously regulating absorption capacities and antioxidant activities of four stilbene derivatives utilizing substitution effect: A theoretical and experimental study against UVB radiation.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  304  (123325).  [PMID:37678043] [10.1016/j.saa.2023.123325]
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14. Hao Guan, Zhiyong Li, Qinlong Xu, Jingjing Meng, Kai Guo.  (2023)  Dual bio-based epoxy resin as green substitute for DGEBA analogue with high performances.  REACTIVE & FUNCTIONAL POLYMERS,  191  (105687).  [10.1016/j.reactfunctpolym.2023.105687]
15. Minghui Cai, Haijuan Sun, Yujia Huang, Haixu Yao, Chen Zhao, Jiao Wang, Hui Zhu.  (2023)  Resveratrol Protects Rat Ovarian Luteinized Granulosa Cells from H2O2-Induced Dysfunction by Activating Autophagy.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (13): (10914).  [PMID:37446088] [10.3390/ijms241310914]
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20. Chen Shengnan, Li Bo, Chen Lei, Jiang Hongli.  (2023)  Uncovering the mechanism of resveratrol in the treatment of diabetic kidney disease based on network pharmacology, molecular docking, and experimental validation.  Journal of Translational Medicine,  21  (1): (1-14).  [PMID:37308949] [10.1186/s12967-023-04233-0]
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26. Ting Qin, Kai Chen, Bingwen Xi, Liangkun Pan, Jun Xie, Liushen Lu, Kai Liu.  (2023)  In Vitro Antibiofilm Activity of Resveratrol against Aeromonas hydrophila.  Antibiotics-Basel,  12  (4): (686).  [PMID:37107048] [10.3390/antibiotics12040686]
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43. Tian Li, Qin Guo, Yang Qu, Hongzhi Liu, Li Liu, Yu Zhang, Qiang Wang.  (2023)  Inhibition mechanism of trans-resveratrol on thermally induced trans fatty acids in peanut oil.  FOOD CHEMISTRY,  406  (134863).  [PMID:36470078] [10.1016/j.foodchem.2022.134863]
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46. Zhongyu Yang, David Julian McClements, Xinwen Peng, Zhenlin Xu, Man Meng, Long Chen, Zhengyu Jin.  (2023)  Fabrication of zein–carboxymethyl cellulose nanoparticles for co-delivery of quercetin and resveratrol.  JOURNAL OF FOOD ENGINEERING,  341  (111322).  [10.1016/j.jfoodeng.2022.111322]
47. Ziting Zhang, You Ji, Nan Hu, Qinqi Yu, Xinrui Zhang, Jie Li, Fenglei Wu, Huae Xu, Qiyun Tang, Xiaolin Li.  (2022)  Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment.  Asian Journal of Pharmaceutical Sciences,  17  (751).  [PMID:36382309] [10.1016/j.ajps.2022.07.006]
48. Dengchao Xie, Xin Zhou, Bo Xiao, Lian Duan, Zhenhua Zhu.  (2022)  Mucus-Penetrating Silk Fibroin-Based Nanotherapeutics for Efficient Treatment of Ulcerative Colitis.  Biomolecules,  12  (9): (1263).  [PMID:36139101] [10.3390/biom12091263]
49. Ningxin Cui, Zhen Xu, Xinyu Zhao, Meng Yuan, Leiyu Pan, Tianfeng Lu, Ai Du, Lili Qin.  (2022)  In Vivo Effect of Resveratrol-Cellulose Aerogel Drug Delivery System to Relieve Inflammation on Sports Osteoarthritis.  Gels,  8  (9): (544).  [PMID:36135256] [10.3390/gels8090544]
50. Lei Wang, Congting Lai, Dong Li, Zisheng Luo, Lingling Liu, Yunbin Jiang, Li Li.  (2022)  Lecithin-Polysaccharide Self-Assembled Microspheres for Resveratrol Delivery.  Antioxidants,  11  (9): (1666).  [PMID:36139740] [10.3390/antiox11091666]
51. Bo Yu, Yiping Shen, Xuejie Zhang, Lijuan Ding, Zheng Meng, Xiaotong Wang, Meihua Han, Yifei Guo, Xiangtao Wang.  (2022)  Poly(methacrylate citric acid) as a Dual Functional Carrier for Tumor Therapy.  Pharmaceutics,  14  (9): (1765).  [PMID:36145512] [10.3390/pharmaceutics14091765]
52. Chunru Wang, Junyao Li, Xiangsheng Han, Shuai Liu, Xintao Gao, Chuanlong Guo, Xiaochen Wu.  (2022)  Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  220  (1021).  [PMID:36007701] [10.1016/j.ijbiomac.2022.08.134]
53. Chengjiang Lu, Shuai Bian, Ke Hu, Caicai Li, Kaiwen Zheng, Qingfeng Sun.  (2022)  Biomass-based epoxy resin derived from resveratrol with high temperature resistance and intrinsic flame retardant properties.  INDUSTRIAL CROPS AND PRODUCTS,  187  (115500).  [10.1016/j.indcrop.2022.115500]
54. Tingting Lin, Ben Chen, Liqun Fang, Haibo You, Chu Chu, Qingsong Shao, Shengqiang Tong.  (2022)  Solvent strength of organic phase for two biphasic solvent systems in high speed countercurrent chromatography.  JOURNAL OF CHROMATOGRAPHY A,  1680  (463422).  [PMID:36037578] [10.1016/j.chroma.2022.463422]
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56. Yu Xu, Wen-Jie Yang, Qian-Kun Zhou, Tian-Yu Gao, Guo-Mei Xu, Qi-Long Tai, San-E Zhu, Hong-Dian Lu, Richard K.K. Yuen, Wei Yang, Chun-Xiang Wei.  (2022)  Highly thermo-stable resveratrol-based flame retardant for enhancing mechanical and fire safety properties of epoxy resins.  CHEMICAL ENGINEERING JOURNAL,  450  (138475).  [10.1016/j.cej.2022.138475]
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