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蛇床子素

具有生物活性的香豆素。抗炎和抗肿瘤活性。
18篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
O101699-1g
 1g 现货 Stock Image
O101699-5g
 5g 现货 Stock Image
O101699-10g
 10g 现货 Stock Image
O101699-25g
 25g 现货 Stock Image
大包装询价 收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
Anti-infection (2825) GPCR/G Protein (3182) HBV (113) Histamine Receptor (191) Immunology/Inflammation (1941) Parasite (431) 六元杂环化合物 (1702) 神经元信号传导 (3329) 苯丙素类 (152)
main product photo

基本描述

别名 7-甲氧基-8-异戊烯基香豆素
英文别名 KBioSS_002022 | NSC 31868 | SDCCGMLS-0066780.P001 | 7-methoxy-8-(3-methylpent-2-enyl)coumarin | A827530 | KBio3_002589 | Spectrum2_000723 | 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- | DivK1c_007042 | AMY40671 | BBL013019 | Osthole (Osthol)
规格或纯度 Moligand™, ≥99%
英文名称 Osthole
生化机理 具有生物活性的香豆素。抗炎和抗肿瘤活性。磷酸肌醇抑制剂和钙通道阻滞剂（IC 50 = 4μM）。抑制NFκB活性以诱导癌细胞的细胞周期停滞和凋亡。
储存温度 室温
运输条件 常规运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

属香豆素类化合物。棱柱状结晶（乙醚）、针状结晶（稀乙醇）。溶于碱溶液、乙醇、氯仿、丙酮等，不溶于水和石油醚。

关联靶点（人）

TRPV3 Tchem 瞬时受体电位阳离子通道亚家族V成员3(Transient receptor potential cation channel subfamily V member 3) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GAPDH Tchem Glyceraldehyde-3-phosphate dehydrogenase liver (1284 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BACE1 Tchem Beta-secretase 1 (15641 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
T47D (39041 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A-431 (6446 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HepG2 (196354 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KB (17409 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HL (112 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
XPO1 Tclin Exportin-1 (375 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Abcb1b P-glycoprotein 1 (174 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mycobacterium tuberculosis (203094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Leishmania major (2877 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Botrytis cinerea (4183 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A10 (235 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MM46 (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
V79 (1637 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
norA Quinolone resistance protein norA (2171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rhizoctonia solani (2251 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PA Polymerase acidic protein (806 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Gabrg2 GABA-A receptor; alpha-1/beta-2/gamma-2 (554 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Colletotrichum camelliae (51 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bactrocera oleae (43 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
mdeA Fluoroquinolone resistance protein (28 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504751915
EC号 610-421-7
分子类型 小分子
IUPAC Name 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
INCHI InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
InChi Key MBRLOUHOWLUMFF-UHFFFAOYSA-N
Canonical SMILES CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
Isomeric SMILES CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
WGK Germany 1
RTECS GN7700000
关联CAS 484-12-8
PubChem CID 10228
NSC Number 31868
MeSH Entry Terms 7-methoxy-8-(3-methylpent-2-enyl)coumarin;osthol;osthole
分子量 244.29
Reaxy-Rn 1288399

化学和物理性质

溶解性 不溶于水；极易溶于甲醇；可溶于乙醇
密度 1.126
沸点 145～150°C
熔点 83-84°C
分子量 244.280 g/mol
XLogP3 3.800
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 244.11 Da
单同位素质量Monoisotopic Mass 244.11 Da
拓扑极表面积Topological Polar Surface Area 35.500 Ų
重原子数Heavy Atom Count 18
形式电荷Formal Charge 0
复杂度Complexity 366.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 1
RTECS GN7700000
Reaxy-Rn 1288399
Merck Index 6895

 SDS英文版

质量标准

Melting point 83-84（℃）
Purity 99-100（%）
Appearance（O101699) Colorless Liquid
Infrared spectrum Conforms to Structure
Proton NMR spectrum Conforms to Structure

 质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到10个结果

批号(Lot Number) 证书类型 日期 货号
L2420812 分析证书 24-07-27 O101699
L2420816 分析证书 24-07-27 O101699
L2420817 分析证书 24-07-27 O101699
A2507147 分析证书 24-07-27 O101699
L2425400 分析证书 24-07-01 O101699
L2425403 分析证书 24-07-01 O101699
D2422168 分析证书 24-04-27 O101699
H2222039 分析证书 23-12-28 O101699
H2222040 分析证书 23-12-28 O101699
H2222041 分析证书 23-12-28 O101699

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?
1. Duo Lai, Delin Wang, Xuehua Shao, Jian Qin, Qingli Zhuang, Hanhong Xu, Weiqiang Xiao.  (2024)  Comparative physiological and transcriptome analysis provide insights into the inhibitory effect of osthole on Penicillium choerospondiatis.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  198  (105749).  [PMID:38225092] [10.1016/j.pestbp.2023.105749]
2. Huang Hui, Xue Jie, Xie Mei-Lin, Xie Tao.  (2023)  Osthole inhibits GSK-3β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice.  STRAHLENTHERAPIE UND ONKOLOGIE,  (1-9).  [PMID:37963994] [10.1007/s00066-023-02173-8]
3. Ke Hu, Rongyu Li, Feixu Mo, Yi Ding, Aiai Zhou, Xue Guo, Ruotong Li, Min Li, Minggui Ou, Ming Li.  (2023)  Natural product osthole can significantly disrupt cell wall integrity and dynamic balance of Fusarium oxysporum.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  196  (105623).  [PMID:37945232] [10.1016/j.pestbp.2023.105623]
4. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu.  (2023)  Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.  ACS Applied Materials & Interfaces,  15  (35): (41287–41298).  [PMID:37632730] [10.1021/acsami.3c06996]
5. Weizhen Wang, Linan He, Zhuzhu Zhang, Wenzhi Li, Jia Chen, Tingting Chen, Youhua Long.  (2023)  Activity of the botanical compound thymol against kiwifruit rot caused by Fusarium tricinctum and the underlying mechanisms.  PEST MANAGEMENT SCIENCE,  [PMID:36864770] [10.1002/ps.7431]
6. Ruige Yang, Zhiyan Liu, Meiyue Han, Liping Cui, Yong Guo.  (2022)  Preparation and Biological Evaluation of Novel Osthole-Derived N-Benzoylthioureas as Insecticide Candidates.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  70  (50): (15737–15746).  [PMID:36508570] [10.1021/acs.jafc.2c06558]
7. Huang Hui, Xue Jie, Xie Tao, Xie Mei-Lin.  (2023)  Osthole increases the radiosensitivity of hepatoma cells by inhibiting GSK-3β/AMPK/mTOR pathway-controlled glycolysis.  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,  396  (4): (683-692).  [PMID:36445387] [10.1007/s00210-022-02347-8]
8. Kuang Yi, Xia Yunlong, Wang Xing, Rao Qingqing, Yang Shengxiang.  (2022)  Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin.  Frontiers in Chemistry,  10  [PMID:35464201] [10.3389/fchem.2022.862777]
9. Pan Liuliu, Zhang Xiaodan, Wang Danhan, Huang Min, Huang Qiusui, Duan Ping, Mei Jie.  (2021)  DCLK1 might be a therapeutic target of osthole against cervical cancer.  PHARMAZIE,  76  (10): (503-506).  [PMID:34620279] [10.1691/ph.2021.1641]
10. Lijun Fang, Wei Wang, Jiazheng Chen, Anju Zuo, Hongmei Gao, Tao Yan, Pengqi Wang, Yujia Lu, Ruijuan Lv, Feng Xu, Yuguo Chen, Linmao Lyu.  (2021)  Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice.  Oxidative Medicine and Cellular Longevity,  2021  (3309944).  [PMID:34527170] [10.1155/2021/3309944]
11. Xing-Hua Zhou, Jian Kang, Zhen-Dong Zhong, Yue Cheng.  (2021)  Osthole induces apoptosis of the HT‑29 cells via endoplasmic reticulum stress and autophagy.  Oncology Letters,  22  (4): (1-9).  [PMID:34429766] [10.3892/ol.2021.12987]
12. Jie Mei, Tiejun Wang, Shaojie Zhao, Yan Zhang.  (2021)  Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7.  Journal of Oncology,  2021  (6610511).  [PMID:33727922] [10.1155/2021/6610511]
13. Yasi Mo, Yong Wu, Xin Li, Hui Rao, Xianxiang Tian, Danni Wu, Zhenpeng Qiu, Guohua Zheng, Junjie Hu.  (2020)  Osthole delays hepatocarcinogenesis in mice by suppressing AKT/FASN axis and ERK phosphorylation.  EUROPEAN JOURNAL OF PHARMACOLOGY,  867  (172788).  [PMID:31712058] [10.1016/j.ejphar.2019.172788]
14. Xiaohong Xu, Vinothakumar Rajamanicham, Sujing Xu, Zhoudi Liu, Tao Yan, Guang Liang, Guilong Guo, Huiping Zhou, Yi Wang.  (2019)  Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway.  BIOMEDICINE & PHARMACOTHERAPY,  115  (108922).  [PMID:31048190] [10.1016/j.biopha.2019.108922]
15. Dai Xuanxuan, Yin Changtian, Zhang Yi, Guo Guilong, Zhao Chengguang, Wang Ouchen, Xiang Youqun, Zhang Xiaohua, Liang Guang.  (2018)  Osthole inhibits triple negative breast cancer cells by suppressing STAT3.  JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,  37  (1): (1-11).  [PMID:30577812] [10.1186/s13046-018-0992-z]
16. Botao Wang, Xin Zheng, Jing Liu, Zhen Zhang, Chongyang Qiu, Lei Yang, Lanqiu Zhang, Qi Zhang, Hongwei Gao, Ximo Wang.  (2018)  Osthole inhibits pancreatic cancer progression by directly exerting negative effects on cancer cells and attenuating tumor-infiltrating M2 macrophages.  JOURNAL OF PHARMACOLOGICAL SCIENCES,  137  (290).  [PMID:30098910] [10.1016/j.jphs.2018.07.007]
17. Yiyi Jin, Jianchang Qian, Xin Ju, Xiaodong Bao, Li Li, Suqing Zheng, Xiong Chen, Zhongxiang Xiao, Xuemei Chen, Weiwei Zhu, Weixin Li, Wencan Wu, Guang Liang.  (2018)  Osthole Protects against Acute Lung Injury by Suppressing NF-κB-Dependent Inflammation.  MEDIATORS OF INFLAMMATION,  2018  (4934592).  [PMID:30057486] [10.1155/2018/4934592]
18. Xu Renguo, Liu Zhen, Hou Jiande, Huang Tao, Yang Ming.  (2018)  Osthole improves collagen-induced arthritis in a rat model through inhibiting inflammation and cellular stress.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  23  (1): (1-11).  [PMID:29743895] [10.1186/s11658-018-0086-0]

参考文献

1. Duo Lai, Delin Wang, Xuehua Shao, Jian Qin, Qingli Zhuang, Hanhong Xu, Weiqiang Xiao.  (2024)  Comparative physiological and transcriptome analysis provide insights into the inhibitory effect of osthole on Penicillium choerospondiatis.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  198  (105749).  [PMID:38225092] [10.1016/j.pestbp.2023.105749]
2. Huang Hui, Xue Jie, Xie Mei-Lin, Xie Tao.  (2023)  Osthole inhibits GSK-3β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice.  STRAHLENTHERAPIE UND ONKOLOGIE,  (1-9).  [PMID:37963994] [10.1007/s00066-023-02173-8]
3. Ke Hu, Rongyu Li, Feixu Mo, Yi Ding, Aiai Zhou, Xue Guo, Ruotong Li, Min Li, Minggui Ou, Ming Li.  (2023)  Natural product osthole can significantly disrupt cell wall integrity and dynamic balance of Fusarium oxysporum.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  196  (105623).  [PMID:37945232] [10.1016/j.pestbp.2023.105623]
4. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu.  (2023)  Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.  ACS Applied Materials & Interfaces,  15  (35): (41287–41298).  [PMID:37632730] [10.1021/acsami.3c06996]
5. Weizhen Wang, Linan He, Zhuzhu Zhang, Wenzhi Li, Jia Chen, Tingting Chen, Youhua Long.  (2023)  Activity of the botanical compound thymol against kiwifruit rot caused by Fusarium tricinctum and the underlying mechanisms.  PEST MANAGEMENT SCIENCE,  [PMID:36864770] [10.1002/ps.7431]
6. Ruige Yang, Zhiyan Liu, Meiyue Han, Liping Cui, Yong Guo.  (2022)  Preparation and Biological Evaluation of Novel Osthole-Derived N-Benzoylthioureas as Insecticide Candidates.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  70  (50): (15737–15746).  [PMID:36508570] [10.1021/acs.jafc.2c06558]
7. Huang Hui, Xue Jie, Xie Tao, Xie Mei-Lin.  (2023)  Osthole increases the radiosensitivity of hepatoma cells by inhibiting GSK-3β/AMPK/mTOR pathway-controlled glycolysis.  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,  396  (4): (683-692).  [PMID:36445387] [10.1007/s00210-022-02347-8]
8. Kuang Yi, Xia Yunlong, Wang Xing, Rao Qingqing, Yang Shengxiang.  (2022)  Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin.  Frontiers in Chemistry,  10  [PMID:35464201] [10.3389/fchem.2022.862777]
9. Pan Liuliu, Zhang Xiaodan, Wang Danhan, Huang Min, Huang Qiusui, Duan Ping, Mei Jie.  (2021)  DCLK1 might be a therapeutic target of osthole against cervical cancer.  PHARMAZIE,  76  (10): (503-506).  [PMID:34620279] [10.1691/ph.2021.1641]
10. Lijun Fang, Wei Wang, Jiazheng Chen, Anju Zuo, Hongmei Gao, Tao Yan, Pengqi Wang, Yujia Lu, Ruijuan Lv, Feng Xu, Yuguo Chen, Linmao Lyu.  (2021)  Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice.  Oxidative Medicine and Cellular Longevity,  2021  (3309944).  [PMID:34527170] [10.1155/2021/3309944]
11. Xing-Hua Zhou, Jian Kang, Zhen-Dong Zhong, Yue Cheng.  (2021)  Osthole induces apoptosis of the HT‑29 cells via endoplasmic reticulum stress and autophagy.  Oncology Letters,  22  (4): (1-9).  [PMID:34429766] [10.3892/ol.2021.12987]
12. Jie Mei, Tiejun Wang, Shaojie Zhao, Yan Zhang.  (2021)  Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7.  Journal of Oncology,  2021  (6610511).  [PMID:33727922] [10.1155/2021/6610511]
13. Yasi Mo, Yong Wu, Xin Li, Hui Rao, Xianxiang Tian, Danni Wu, Zhenpeng Qiu, Guohua Zheng, Junjie Hu.  (2020)  Osthole delays hepatocarcinogenesis in mice by suppressing AKT/FASN axis and ERK phosphorylation.  EUROPEAN JOURNAL OF PHARMACOLOGY,  867  (172788).  [PMID:31712058] [10.1016/j.ejphar.2019.172788]
14. Xiaohong Xu, Vinothakumar Rajamanicham, Sujing Xu, Zhoudi Liu, Tao Yan, Guang Liang, Guilong Guo, Huiping Zhou, Yi Wang.  (2019)  Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway.  BIOMEDICINE & PHARMACOTHERAPY,  115  (108922).  [PMID:31048190] [10.1016/j.biopha.2019.108922]
15. Dai Xuanxuan, Yin Changtian, Zhang Yi, Guo Guilong, Zhao Chengguang, Wang Ouchen, Xiang Youqun, Zhang Xiaohua, Liang Guang.  (2018)  Osthole inhibits triple negative breast cancer cells by suppressing STAT3.  JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,  37  (1): (1-11).  [PMID:30577812] [10.1186/s13046-018-0992-z]
16. Botao Wang, Xin Zheng, Jing Liu, Zhen Zhang, Chongyang Qiu, Lei Yang, Lanqiu Zhang, Qi Zhang, Hongwei Gao, Ximo Wang.  (2018)  Osthole inhibits pancreatic cancer progression by directly exerting negative effects on cancer cells and attenuating tumor-infiltrating M2 macrophages.  JOURNAL OF PHARMACOLOGICAL SCIENCES,  137  (290).  [PMID:30098910] [10.1016/j.jphs.2018.07.007]
17. Yiyi Jin, Jianchang Qian, Xin Ju, Xiaodong Bao, Li Li, Suqing Zheng, Xiong Chen, Zhongxiang Xiao, Xuemei Chen, Weiwei Zhu, Weixin Li, Wencan Wu, Guang Liang.  (2018)  Osthole Protects against Acute Lung Injury by Suppressing NF-κB-Dependent Inflammation.  MEDIATORS OF INFLAMMATION,  2018  (4934592).  [PMID:30057486] [10.1155/2018/4934592]
18. Xu Renguo, Liu Zhen, Hou Jiande, Huang Tao, Yang Ming.  (2018)  Osthole improves collagen-induced arthritis in a rat model through inhibiting inflammation and cellular stress.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  23  (1): (1-11).  [PMID:29743895] [10.1186/s11658-018-0086-0]

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