| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N408054-1ml |
1ml |
期货  |
|
| 别名 | 萘夫西林钠 |
|---|---|
| 英文别名 | CL 8491 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S,5R,6R)- |
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | Nafcillin Sodium |
| 生化机理 | 萘夫西林钠（CL 8491）对 β-内酰胺酶有可逆抑制作用，Kd为 33 mM。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
An antibiotic resistant to beta-lactamase. Information Nafcillin Sodium Nafcillin sodium (CL 8491) reversibly inhibits β-lactamase with K d of 33 mM. Nafcillin sodium inactivates β-lactamase through forming a covalent acyl-enzyme intermediate with β-lactamase via Ser-70. At concentrations above 80 mM, Nafcillin displays complete inhibition of β-lactamase within 200 s. Upon removal of the excess Nafcillin, the inhibited enzyme can be re-activated completely, with a rate constant of 2×10-3/s (25 ℃). Nafcillin sodium is activity against penicillin-resistant staphylococci. The minimal concentration necessary for antistaphylococcic activity in vitro ranges from 0.2 μg/mL to 2 μg/mL. In vivo
cell lines： Concentrations： Incubation Time： Powder Purity:≥99% |
| Canonical SMILES | O.CCOC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C4=C(C=CC=C4)C=C1 |
|---|---|
| 分子量 | 454.47 |
| Concentration(Compounding value) | 9-11(mmol/L) |
|---|---|
| Record the entire process by video | Conform |
首页
400-620-6333
