按标签分类的文章 "γ-Secretase Inhibitors"

1. γ-Secretase Inhibitors
   发布于 2025年8月20日

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   γ-Secretase is a multi-subunit enzyme complex that catalyzes the cleavage of various transmembrane proteins, including amyloid precursor protein (APP) and Notch. Processing of APP by γ-secretase leads to the production of amyloid-β peptides, which aggregate to form the amyloid plaques that are a ...