按标签分类的文章 "MBLs"

1. The process path of EBL-3183: from indole to preclinical inhibitor
   发布于 2024年3月1日

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   Metallo-β-lactamases (MBLs) are regarded as major determinants of carbapenem antibiotic resistance. Therefore, the search for new MBL inhibitors has become an urgent task at present. Recently, Prof. Andrei Baran and his team published an article in Org. Process Res. Dev, detailing the synthetic ...
2. EBL-3183的工艺之路：从吲哚到临床前抑制剂
   发布于 2024年3月1日

   2
   金属β-内酰胺酶（MBLs）被视为决定碳青霉烯抗生素抗药性的主要因素。因此，寻找新的MBL抑制剂成为当前的紧迫任务。近期，Andrei Baran教授及其团队在Org. Process Res. ...