胞苷-5'磷酸(5'-CMP)

  • ≥99%
有货

库存信息

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库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
C101008-1g
1g 现货 Stock Image
C101008-5g
5g 现货 Stock Image

基本描述

别名 胞苷酸
英文别名 CMP | 5'-CMP | CYTIDINE-5''-MONOPHOSPHATE | Cytidine-5'-monophosphate | FN5 | Cytidine 5'-phosphoric acid | EINECS 200-556-6 | Q412622 | [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate | AKOS015888565 |
规格或纯度 ≥99%
英文名称 Cytidine 5'-monophosphate
应用 用于生化研究
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

易溶于水,不溶于乙醇,具有高度生物活性,能促进细胞代谢,升白细胞,提高人体免疫力。 用于生化研究


关联靶点(人)

UCK2 Tbio Uridine-cytidine kinase 2 (58 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RNASE1 Tchem Ribonuclease pancreatic (45 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UMPS Tclin Uridine 5'-monophosphate synthase (20 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CMPK1 Tchem UMP-CMP kinase (152 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

St6gal1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase (61 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (29 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
B16 (5829 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L1210 (27553 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L1210/ara C (6 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ompdc Orotidine phosphate decarboxylase (9 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
pyrF Orotidine 5'-phosphate decarboxylase (39 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SRN Seminal ribonuclease (5 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504751007
EC号 200-556-6
分子类型 小分子
IUPAC Name [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
INCHI InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChi Key IERHLVCPSMICTF-XVFCMESISA-N
Canonical SMILES C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O
Isomeric SMILES C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
WGK Germany 3
RTECS HA3980000
PubChem CID 6131
分子量 323.2
Beilstein号 46982
Reaxy-Rn 46982

化学和物理性质

密度 2.155
比旋光度 9.8 ° (C=1, 0.5mol/L Na2HPO4)
分子量 323.200 g/mol
XLogP3 -3.400
氢键供体数Hydrogen Bond Donor Count 5
氢键受体数Hydrogen Bond Acceptor Count 8
可旋转键计数Rotatable Bond Count 4
精确质量Exact Mass 323.052 Da
单同位素质量Monoisotopic Mass 323.052 Da
拓扑极表面积Topological Polar Surface Area 175.000 Ų
重原子数Heavy Atom Count 21
形式电荷Formal Charge 0
复杂度Complexity 531.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 4
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
RTECS HA3980000
Reaxy-Rn 46982
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质量标准

Specific Rotation [a]20/D(c=1 in 0.5mol/L Na2HPO4 sol.) 9-10.5(°)
Purity(HPLC) 98-100(%)
Heavy metal(as Pb) 0-10(ppm)
Phosphorus(anhydrous) 9-9.8(%)
Loss on drying 0-3(%)
Appearance(C101008) White to Off-White Powder or Crystals
Infrared spectrum Conforms to Structure
Solubility in 1 M NH4OH,Colorless,Clear,50 mg/ml pass

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到4个结果

批号(Lot Number) 证书类型 日期 货号
L2001136 分析证书 24-09-06 C101008
L2001137 分析证书 24-09-05 C101008
C1622040 分析证书 23-10-09 C101008
C1812029 分析证书 22-01-27 C101008

此产品的引用文献

1. Yujuan Ren, Kaiwen Zhao, Guangyao Wu, Lianghai Hu.  (2023)  Highly Ordered Assembly of Templates on Molecular Imprinting toward Phosphorylated Compounds for Improved Performance.  ACS Applied Polymer Materials,  [10.1021/acsapm.3c02841]
2. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,  (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
3. Tiantian Tang, Min Zhang, Yaping Liu.  (2023)  Valorization of meat and bone residue by ultrasound and high voltage electrostatic field assisted two-stage enzymatic hydrolysis: Nutritional characteristics and flavor analysis.  Food Bioscience,  56  (103203).  [10.1016/j.fbio.2023.103203]
4. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang.  (2023)  A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function.  Nature Communications,  14  (1): (1-14).  [PMID:37419896] [10.1038/s41467-023-39779-6]
5. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu.  (2023)  A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment.  Advanced Science,  10  (9): (2206851).  [PMID:36709479] [10.1002/advs.202206851]
6. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang.  (2022)  Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore.  ACS Nano,  16  (12): (21356–21365).  [PMID:36475606] [10.1021/acsnano.2c09662]
7. Yafei Hou, Xiaodan Pei, Yuancheng Wang, Luyuan Zhang, Xiaohui Wei, Hongyan Mao, Wuduo Zhao, Shusheng Zhang, Wenfen Zhang.  (2022)  Selective Detection of Nucleotides in Infant Formula Using an N-Rich Covalent Triazine Porous Polymer.  Nanomaterials,  12  (13): (2213).  [PMID:35808047] [10.3390/nano12132213]
8. Jianghong Wu, Min Zhang, Lihui Zhang, Yaping Liu.  (2022)  Effect of ultrasound combined with sodium bicarbonate pretreatment on the taste and flavor of chicken broth.  JOURNAL OF FOOD PROCESS ENGINEERING,  46  (6): (e14072).  [10.1111/jfpe.14072]
9. Cheng Huang, Guanglei Zhao, Yanghui Song, Chong Xie, Sihan Zhang, Xiaofeng Li.  (2022)  Preparation of Novel Biodegradable Cellulose Nanocrystal Proton Exchange Membranes for Direct Methanol Fuel-Cell Applications.  ACS Sustainable Chemistry & Engineering,  10  (17): (5559–5568).  [10.1021/acssuschemeng.2c00221]
10. Hui Hou, Chang Liu, Xiaoshuo Lu, Donglu Fang, Qiuhui Hu, Yuyu Zhang, Liyan Zhao.  (2021)  Characterization of flavor frame in shiitake mushrooms (Lentinula edodes) detected by HS-GC-IMS coupled with electronic tongue and sensory analysis: Influence of drying techniques.  LWT-FOOD SCIENCE AND TECHNOLOGY,  146  (111402).  [10.1016/j.lwt.2021.111402]
11. Chen Pengfei, Wu Jing, Zhou Lei, Pu Qiaosheng.  (2021)  In situ controllable synthesis of Schiff base networks porous polymer coatings for open-tubular capillary electrochromatography.  MICROCHIMICA ACTA,  188  (3): (1-9).  [PMID:33586055] [10.1007/s00604-021-04740-1]
12. Mei He, Ma Yange, Wu Huimin, Wang Xuedong.  (2021)  Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (8): (2135-2146).  [PMID:33511458] [10.1007/s00216-021-03181-2]
13. Hongying Li, Qiujin Zhu, Rui Chang, Ke Hu, Xuling Zhu, Aqi Xu, Shitao Xu, Pengyu Tang.  (2021)  Effects of Dietary 5′-CMP on Neu5Gc Contents in the Muscle and Viscera of Xiang Pigs.  JOURNAL OF FOOD PROTECTION,  84  (23).  [PMID:33393618] [10.4315/JFP-20-191]
14. Fang Pu, Songrong Qu, Hao Qiu, Lu Zhang.  (2020)  Regulation of light-harvesting antenna based on silver ion-enhanced emission of dye-doped coordination polymer nanoparticles.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  578  (254).  [PMID:32531555] [10.1016/j.jcis.2020.05.083]
15. Fang Pu, Yanyan Huang, Zhiguang Yang, Hao Qiu, Jinsong Ren.  (2018)  Nucleotide-Based Assemblies for Green Synthesis of Silver Nanoparticles with Controlled Localized Surface Plasmon Resonances and Their Applications.  ACS Applied Materials & Interfaces,  10  (12): (9929–9937).  [PMID:29494122] [10.1021/acsami.7b18915]
16. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang.  (2017)  Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency.  JOURNAL OF CHROMATOGRAPHY A,  1509  (83).  [PMID:28629939] [10.1016/j.chroma.2017.06.034]
17. Ruiyong Wang, Xiaogai Wang, Zhigang Li, Yuanzhe Xie, Lingling Yang, Jie Shi, Junbiao Chang.  (2014)  Study on the interaction between bovine serum albumin and 4′-azido-2′-deoxyfluoroarabinocytidine or analogs by spectroscopy and molecular modeling.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  132  (786).  [PMID:24971719] [10.1016/j.saa.2014.05.090]

参考文献

1. Yujuan Ren, Kaiwen Zhao, Guangyao Wu, Lianghai Hu.  (2023)  Highly Ordered Assembly of Templates on Molecular Imprinting toward Phosphorylated Compounds for Improved Performance.  ACS Applied Polymer Materials,  [10.1021/acsapm.3c02841]
2. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,  (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
3. Tiantian Tang, Min Zhang, Yaping Liu.  (2023)  Valorization of meat and bone residue by ultrasound and high voltage electrostatic field assisted two-stage enzymatic hydrolysis: Nutritional characteristics and flavor analysis.  Food Bioscience,  56  (103203).  [10.1016/j.fbio.2023.103203]
4. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang.  (2023)  A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function.  Nature Communications,  14  (1): (1-14).  [PMID:37419896] [10.1038/s41467-023-39779-6]
5. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu.  (2023)  A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment.  Advanced Science,  10  (9): (2206851).  [PMID:36709479] [10.1002/advs.202206851]
6. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang.  (2022)  Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore.  ACS Nano,  16  (12): (21356–21365).  [PMID:36475606] [10.1021/acsnano.2c09662]
7. Yafei Hou, Xiaodan Pei, Yuancheng Wang, Luyuan Zhang, Xiaohui Wei, Hongyan Mao, Wuduo Zhao, Shusheng Zhang, Wenfen Zhang.  (2022)  Selective Detection of Nucleotides in Infant Formula Using an N-Rich Covalent Triazine Porous Polymer.  Nanomaterials,  12  (13): (2213).  [PMID:35808047] [10.3390/nano12132213]
8. Jianghong Wu, Min Zhang, Lihui Zhang, Yaping Liu.  (2022)  Effect of ultrasound combined with sodium bicarbonate pretreatment on the taste and flavor of chicken broth.  JOURNAL OF FOOD PROCESS ENGINEERING,  46  (6): (e14072).  [10.1111/jfpe.14072]
9. Cheng Huang, Guanglei Zhao, Yanghui Song, Chong Xie, Sihan Zhang, Xiaofeng Li.  (2022)  Preparation of Novel Biodegradable Cellulose Nanocrystal Proton Exchange Membranes for Direct Methanol Fuel-Cell Applications.  ACS Sustainable Chemistry & Engineering,  10  (17): (5559–5568).  [10.1021/acssuschemeng.2c00221]
10. Hui Hou, Chang Liu, Xiaoshuo Lu, Donglu Fang, Qiuhui Hu, Yuyu Zhang, Liyan Zhao.  (2021)  Characterization of flavor frame in shiitake mushrooms (Lentinula edodes) detected by HS-GC-IMS coupled with electronic tongue and sensory analysis: Influence of drying techniques.  LWT-FOOD SCIENCE AND TECHNOLOGY,  146  (111402).  [10.1016/j.lwt.2021.111402]
11. Chen Pengfei, Wu Jing, Zhou Lei, Pu Qiaosheng.  (2021)  In situ controllable synthesis of Schiff base networks porous polymer coatings for open-tubular capillary electrochromatography.  MICROCHIMICA ACTA,  188  (3): (1-9).  [PMID:33586055] [10.1007/s00604-021-04740-1]
12. Mei He, Ma Yange, Wu Huimin, Wang Xuedong.  (2021)  Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (8): (2135-2146).  [PMID:33511458] [10.1007/s00216-021-03181-2]
13. Hongying Li, Qiujin Zhu, Rui Chang, Ke Hu, Xuling Zhu, Aqi Xu, Shitao Xu, Pengyu Tang.  (2021)  Effects of Dietary 5′-CMP on Neu5Gc Contents in the Muscle and Viscera of Xiang Pigs.  JOURNAL OF FOOD PROTECTION,  84  (23).  [PMID:33393618] [10.4315/JFP-20-191]
14. Fang Pu, Songrong Qu, Hao Qiu, Lu Zhang.  (2020)  Regulation of light-harvesting antenna based on silver ion-enhanced emission of dye-doped coordination polymer nanoparticles.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  578  (254).  [PMID:32531555] [10.1016/j.jcis.2020.05.083]
15. Fang Pu, Yanyan Huang, Zhiguang Yang, Hao Qiu, Jinsong Ren.  (2018)  Nucleotide-Based Assemblies for Green Synthesis of Silver Nanoparticles with Controlled Localized Surface Plasmon Resonances and Their Applications.  ACS Applied Materials & Interfaces,  10  (12): (9929–9937).  [PMID:29494122] [10.1021/acsami.7b18915]
16. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang.  (2017)  Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency.  JOURNAL OF CHROMATOGRAPHY A,  1509  (83).  [PMID:28629939] [10.1016/j.chroma.2017.06.034]
17. Ruiyong Wang, Xiaogai Wang, Zhigang Li, Yuanzhe Xie, Lingling Yang, Jie Shi, Junbiao Chang.  (2014)  Study on the interaction between bovine serum albumin and 4′-azido-2′-deoxyfluoroarabinocytidine or analogs by spectroscopy and molecular modeling.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  132  (786).  [PMID:24971719] [10.1016/j.saa.2014.05.090]

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