页面 5 | HIF/HIF脯氨酰羟化酶 - 代谢酶/蛋白酶 - 按“信号通路”分类

短杆菌肽 A

规格或纯度 :

≥90%

CAS号: 11029-61-1 Compound CID : 16132269

分子式: C₉₉H₁₄₀N₂₀O₁₇ 分子量: 1882.29

IUPAC Name: (2R)-2-[[(2S)-2-[[2-[[(2S)-2-formamido-3-methylbutanoyl]amino]acetyl]amino]propanoyl]amino]-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-(2-hydroSee more

SMILES: CC(C)CC(C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(C)C)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NC(CC(C)C)C(=O)NC(CC7=CNSee more

InChIKey: ZWCXYZRRTRDGQE-LUPIJMBPSA-N

InChI: 1S/C99H140N20O17/c1-51(2)37-73(109-86(123)59(17)107-81(122)49-105-96(133)82(55(9)10)106-50-121)89(126)108-60(18)87(124)117-84(57(13)14)98(135)119-85(58(15)16)99(136)118-83(56(11)12)97(134)116-80(44-64See more

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棘霉素HIF-1α抑制剂

规格或纯度 :

≥98%

CAS号: 512-64-1

分子式: C₅₁H₆₄N₁₂O₁₂S₂ 分子量: 1101.26

IUPAC Name: N-[2,4,12,15,17,25-hexamethyl-27-methylsulfanyl-3,6,10,13,16,19,23,26-octaoxo-11,24-di(propan-2-yl)-20-(quinoxaline-2-carbonylamino)-9,22-dioxa-28-thia-2,5,12,15,18,25-hexazabicyclo[12.12.3]nonacosan-See more

SMILES: CC1C(=O)N(C2CSC(C(C(=O)N(C(C(=O)OCC(C(=O)N1)NC(=O)C3=NC4=CC=CC=C4N=C3)C(C)C)C)N(C(=O)C(NC(=O)C(COC(=O)C(N(C2=O)C)C(C)C)NC(=O)C5=NC6=CC=CC=C6N=C5)C)C)SC)C

InChIKey: AUJXLBOHYWTPFV-UHFFFAOYSA-N

InChI: 1S/C51H64N12O12S2/c1-25(2)38-49(72)74-22-36(59-42(65)34-21-53-30-17-13-15-19-32(30)57-34)44(67)55-28(6)46(69)63(10)40-48(71)62(9)39(26(3)4)50(73)75-23-35(58-41(64)33-20-52-29-16-12-14-18-31(29)56-33)4See more

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ML 228,HIF通路激活剂

规格或纯度 :

≥98%(HPLC)

CAS号: 1357171-62-0

分子式: C₂₇H₂₁N₅ 分子量: 415.49

IUPAC Name: 6-phenyl-N-[(4-phenylphenyl)methyl]-3-pyridin-2-yl-1,2,4-triazin-5-amine

SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=C(N=NC(=N3)C4=CC=CC=N4)C5=CC=CC=C5

InChIKey: QNRODODTMXCRKU-UHFFFAOYSA-N

InChI: 1S/C27H21N5/c1-3-9-21(10-4-1)22-16-14-20(15-17-22)19-29-27-25(23-11-5-2-6-12-23)31-32-26(30-27)24-13-7-8-18-28-24/h1-18H,19H2,(H,29,30,32)

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KC7F2,HIF-1α抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号: 927822-86-4

分子式: C₁₆H₁₆Cl₄N₂O₄S₄ 分子量: 570.38

IUPAC Name: 2,5-dichloro-N-[2-[2-[(2,5-dichlorophenyl)sulfonylamino]ethyldisulfanyl]ethyl]benzenesulfonamide

SMILES: C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl

InChIKey: REQLACDIZMLXIC-UHFFFAOYSA-N

InChI: 1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2

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GN 44028,HIF-1α抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号: 1421448-26-1

分子式: C₁₈N₁₅N₃O₂ 分子量: 305.33

IUPAC Name: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

SMILES: C1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54

InChIKey: CGZKSZVSWAAUHE-UHFFFAOYSA-N

InChI: 1S/C18H15N3O2/c1-2-4-13-11(3-1)9-14-17(13)20-21-18(14)19-12-5-6-15-16(10-12)23-8-7-22-15/h1-6,10H,7-9H2,(H2,19,20,21)

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BAY 87-2243,线粒体复合物I抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号: 1227158-85-1

分子式: C₂₆H₂₆F₃N₇O₂ 分子量: 525.54

IUPAC Name: 5-[1-[[2-(4-cyclopropylpiperazin-1-yl)pyridin-4-yl]methyl]-5-methylpyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole

SMILES: CC1=CC(=NN1CC2=CC(=NC=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(C=C6)OC(F)(F)F

InChIKey: CDJNNOJINJAXPV-UHFFFAOYSA-N

InChI: 1S/C26H26F3N7O2/c1-17-14-22(25-31-24(33-38-25)19-2-6-21(7-3-19)37-26(27,28)29)32-36(17)16-18-8-9-30-23(15-18)35-12-10-34(11-13-35)20-4-5-20/h2-3,6-9,14-15,20H,4-5,10-13,16H2,1H3

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Adaptaquin,HIF-脯氨酰羟化酶2（PHD2）抑制剂

规格或纯度 :

≥97%(HPLC)

CAS号: 385786-48-1

分子式: C₂₁H₁₆ClN₃O₂ 分子量: 377.82

IUPAC Name: 7-[(4-chlorophenyl)-[(3-hydroxypyridin-2-yl)amino]methyl]quinolin-8-ol

SMILES: C1=CC2=C(C(=C(C=C2)C(C3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)O)O)N=C1

InChIKey: KKYHNYRUBSYTCZ-UHFFFAOYSA-N

InChI: 1S/C21H16ClN3O2/c22-15-8-5-14(6-9-15)18(25-21-17(26)4-2-12-24-21)16-10-7-13-3-1-11-23-19(13)20(16)27/h1-12,18,26-27H,(H,24,25)

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GSK360A

CAS号: 931399-19-8

分子式: C₁₇H₁₇FN₂O₅ 分子量: 348.33

IUPAC Name: 2-[[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxoquinoline-3-carbonyl]amino]acetic acid

SMILES: C1CC1CCN2C3=C(C=C(C=C3)F)C(=C(C2=O)C(=O)NCC(=O)O)O

InChIKey: TYHRZQVUPPODPT-UHFFFAOYSA-N

InChI: 1S/C17H17FN2O5/c18-10-3-4-12-11(7-10)15(23)14(16(24)19-8-13(21)22)17(25)20(12)6-5-9-1-2-9/h3-4,7,9,23H,1-2,5-6,8H2,(H,19,24)(H,21,22)

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氨磷汀三水合物

规格或纯度 :

≥97%

CAS号: 112901-68-5

分子式: C₅H₁₅N₂O₃PS·3H₂O 分子量: 268.27

IUPAC Name: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate

SMILES: C(CN)CNCCSP(=O)(O)O.O.O.O

InChIKey: TXQPXJKRNHJWAX-UHFFFAOYSA-N

InChI: 1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2

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葫芦素B

规格或纯度 :

Moligand™

≥98%

CAS号: 6199-67-3 EC号: 683-121-7

分子式: C₃₂H₄₆O₈ 分子量: 558.7

IUPAC Name: [(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acSee more

SMILES: CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O

InChIKey: IXQKXEUSCPEQRD-DKRGWESNSA-N

InChI: 1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,2See more

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1,4-DPCA

规格或纯度 :

≥98%

CAS号: 331830-20-7

分子式: C₁₃H₈N₂O₃ 分子量: 240.21

IUPAC Name: 4-oxo-1H-1,10-phenanthroline-3-carboxylic acid

SMILES: C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1

InChIKey: XZZHOJONZJQARN-UHFFFAOYSA-N

InChI: 1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)

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11-羰基-β-乙酰乳香酸

规格或纯度 :

Moligand™

≥98%

CAS号: 67416-61-9

分子式: C₃₂H₄₈O₅ 分子量: 512.74

IUPAC Name: (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

SMILES: CC1CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C

InChIKey: HMMGKOVEOFBCAU-BCDBGHSCSA-N

InChI: 1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)/t18-,19+,23-,24-,25+,26-,28-,29+,See more

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