首页
400-620-6333
Ras
-
LC-2CAS号: 2502156-03-6 Compound CID : 154727765分子式: C59H71ClFN11O7S 分子量: 1132.78IUPAC Name: See more
SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCOCCCN4CCCC4COC5=NC6=C(CCN(C6)C7=CC=CC8=C7C(=CC=C8)Cl)C(=N5)N9CCN(C(C9)CC#N)C(=O)C(=C)F)OInChIKey: ZCGQZLKPUVGCBQ-HLMPTVQRSA-NInChI: See more -
6H05 (TFA)CAS号: 2061344-88-3 Compound CID : 86208069分子式: C20H30ClN3O2S3.CF3COOH 分子量: 590.14IUPAC Name: 1-[2-(4-chlorophenyl)sulfanylacetyl]-N-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide;2,2,2-trifluoroacetic acidSMILES: CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC2=CC=C(C=C2)Cl.C(=O)(C(F)(F)F)OInChIKey: YNMYIJSFFJXIRV-UHFFFAOYSA-NInChI: 1S/C20H30ClN3O2S3.C2HF3O2/c1-23(2)12-14-29-28-13-9-22-20(26)16-7-10-24(11-8-16)19(25)15-27-18-5-3-17(21)4-6-18;3-2(4,5)1(6)7/h3-6,16H,7-15H2,1-2H3,(H,22,26);(H,6,7)
-
K-Ras（G12C）抑制剂12CAS号: 1469337-95-8分子式: C15H17ClIN3O3 分子量: 449.67IUPAC Name: 1-[4-[2-(4-chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-oneSMILES: C=CC(=O)N1CCN(CC1)C(=O)CNC2=CC(=C(C=C2O)Cl)IInChIKey: JFIFBWVNHLXJFY-UHFFFAOYSA-NInChI: 1S/C15H17ClIN3O3/c1-2-14(22)19-3-5-20(6-4-19)15(23)9-18-12-8-11(17)10(16)7-13(12)21/h2,7-8,18,21H,1,3-6,9H2
-
K-Ras（G12C）抑制剂6CAS号: 2060530-16-5分子式: C17H22Cl2N2O3S 分子量: 405.34IUPAC Name: N-[1-[2-(2,4-dichlorophenoxy)acetyl]piperidin-4-yl]-4-sulfanylbutanamideSMILES: C1CN(CCC1NC(=O)CCCS)C(=O)COC2=C(C=C(C=C2)Cl)ClInChIKey: ZPXCEHMKUTXHRZ-UHFFFAOYSA-NInChI: 1S/C17H22Cl2N2O3S/c18-12-3-4-15(14(19)10-12)24-11-17(23)21-7-5-13(6-8-21)20-16(22)2-1-9-25/h3-4,10,13,25H,1-2,5-9,11H2,(H,20,22)
-
FTI 277 盐酸盐CAS号: 180977-34-8 Compound CID : 88309922分子式: C22H30ClN3O3S2 分子量: 484.07IUPAC Name: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate;hydrochlorideSMILES: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.ClInChIKey: PIAFFJUUNXEDEW-PXPMWPIZSA-NInChI: 1S/C22H29N3O3S2.ClH/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15;/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26);1H/t16-,20+;/m1./s1
-
BQU57CAS号: 1637739-82-2分子式: C16H13F3N4O 分子量: 334.1IUPAC Name: 6-amino-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-4H-pyrano[2,3-c]pyrazole-5-carbonitrileSMILES: CC1=NN(C2=C1C(C(=C(O2)N)C#N)C3=CC=C(C=C3)C(F)(F)F)CInChIKey: IJCMHHSFXFMZAI-UHFFFAOYSA-NInChI: 1S/C16H13F3N4O/c1-8-12-13(9-3-5-10(6-4-9)16(17,18)19)11(7-20)14(21)24-15(12)23(2)22-8/h3-6,13H,21H2,1-2H3
-
ARS-853 (ARS853)CAS号: 1629268-00-3分子式: C22H29ClN4O3 分子量: 432.94IUPAC Name: 1-[3-[4-[2-[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)anilino]acetyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-oneSMILES: CC1(CC1)C2=CC(=C(C=C2Cl)O)NCC(=O)N3CCN(CC3)C4CN(C4)C(=O)C=CInChIKey: IPFOCHMOYUMURK-UHFFFAOYSA-NInChI: 1S/C22H29ClN4O3/c1-3-20(29)27-13-15(14-27)25-6-8-26(9-7-25)21(30)12-24-18-10-16(22(2)4-5-22)17(23)11-19(18)28/h3,10-11,15,24,28H,1,4-9,12-14H2,2H3
-
ARS-1620CAS号: 1698055-85-4分子式: C21H17ClF2N4O2 分子量: 430.84IUPAC Name: 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]prop-2-en-1-oneSMILES: C=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)FInChIKey: ZRPZPNYZFSJUPA-UHFFFAOYSA-NInChI: 1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
-
MBQ-167CAS号: 2097938-73-1分子式: C22H18N4 分子量: 338.41IUPAC Name: 9-ethyl-3-(5-phenyltriazol-1-yl)carbazoleSMILES: CCN1C2=C(C=C(C=C2)N3C(=CN=N3)C4=CC=CC=C4)C5=CC=CC=C51InChIKey: LJCANTASZGYJLG-UHFFFAOYSA-NInChI: 1S/C22H18N4/c1-2-25-20-11-7-6-10-18(20)19-14-17(12-13-21(19)25)26-22(15-23-24-26)16-8-4-3-5-9-16/h3-15H,2H2,1H3
-
索托拉西布（AMG510）CAS号: 2296729-00-3 Compound CID : 137278711分子式: C30H30F2N6O3 分子量: 560.59IUPAC Name: 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-oneSMILES: CC1CN(CCN1C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)O)C5=C(C=CN=C5C(C)C)C)C(=O)C=CInChIKey: NXQKSXLFSAEQCZ-SFHVURJKSA-NInChI: 1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
-
MRTX-1257CAS号: 2206736-04-9分子式: C33H39N7O2 分子量: 565.71IUPAC Name: 2-[(2S)-4-[7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-prop-2-enoylpiperazin-2-yl]acetonitrileSMILES: CC1=C2C(=CC=C1)C=CC=C2N3CCC4=C(C3)N=C(N=C4N5CCN(C(C5)CC#N)C(=O)C=C)OCC6CCCN6CInChIKey: YRYQLVCTQFBRLD-UIOOFZCWSA-NInChI: See more
-
ZT-12-037-01CAS号: 2328073-61-4 Compound CID : 138911316分子式: C21H31N5O2 分子量: 385.5IUPAC Name: 2-N-cyclopropyl-6,7-dimethoxy-4-N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamineSMILES: CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)NC4CC4InChIKey: AMAQJTHMSLYMFT-UHFFFAOYSA-NInChI: 1S/C21H31N5O2/c1-13(2)26-9-7-15(8-10-26)22-20-16-11-18(27-3)19(28-4)12-17(16)24-21(25-20)23-14-5-6-14/h11-15H,5-10H2,1-4H3,(H2,22,23,24,25)
