| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| B424921-1ml |
1ml |
现货  |
|
| 英文别名 | BRADYKININ | 58-82-2 | Kallidin I | L-Bradykinin | Callidin I | Synthetic bradykinin | Bradykinin (synthetic) | Kallidin 9 | RPPGFSPFR | BRS 640 | PRS 640 | (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrol |
|---|---|
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Bradykinin |
| 生化机理 | 内源缓激肽受体激动剂，对B2的选择性高于B1受体。促炎肽。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 激动剂 |
| 作用机制 | B 1 受体激动剂;B 2 受体激动剂 |
| 产品介绍 |
Bradykinin是由激肽释放酶-激肽系统产生的活性肽。 它是炎症调节因子，也被认为是几种血管和肾功能以及神经调节因子。 Bradykinin is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 200-398-8 |
|---|---|
| 分子类型 | 蛋白质 |
| IUPAC Name | (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid |
| INCHI | InChI=1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1 |
| InChi Key | QXZGBUJJYSLZLT-FDISYFBBSA-N |
| Canonical SMILES | C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O |
| Isomeric SMILES | C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O |
| 关联CAS | 58-82-2,5979-11-3 (triacetate (salt)) |
| PubChem CID | 439201 |
| MeSH Entry Terms | Arg Pro Pro Gly Phe Ser Pro Phe Arg;Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg;Bradykinin;Bradykinin Acetate, (9-D-Arg)-Isomer;Bradykinin Diacetate;Bradykinin Hydrochloride;Bradykinin Triacetate;Bradykinin, (1-D-Arg)-Isomer;Bradykinin, (2-D-Pro)-Isomer;Bradykini |
| 分子量 | 1060.21 |
| 分子量 | 1060.200 g/mol |
|---|---|
| XLogP3 | -4.800 |
| 氢键供体数Hydrogen Bond Donor Count | 12 |
| 氢键受体数Hydrogen Bond Acceptor Count | 14 |
| 可旋转键计数Rotatable Bond Count | 27 |
| 精确质量Exact Mass | 1059.56 Da |
| 单同位素质量Monoisotopic Mass | 1059.56 Da |
| 拓扑极表面积Topological Polar Surface Area | 419.000 Ų |
| 重原子数Heavy Atom Count | 76 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 2080.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 8 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| Concentration(Compounding value) | |
|---|---|
| Record the entire process by video | conform |
| 1. Jiawen Ai, Weize Zhao, Quan Yu, Xiang Qian, Jianhua Zhou, Xinming Huo, Fei Tang. (2023) SR-Unet: A Super-Resolution Algorithm for Ion Trap Mass Spectrometers Based on the Deep Neural Network. ANALYTICAL CHEMISTRY, 95 (47): (17407–17415). [PMID:37963290] [10.1021/acs.analchem.3c04172] |
| 2. Xi-Tian Peng, Bi-Feng Yuan, Yu-Qi Feng. (2011) Grafting of silica with a hydrophilic triol acrylamide polymer via surface-initiated “grafting from” method for hydrophilic-interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 34 (22): (3123-3130). [PMID:21998034] [10.1002/jssc.201100570] |
| 1. Jiawen Ai, Weize Zhao, Quan Yu, Xiang Qian, Jianhua Zhou, Xinming Huo, Fei Tang. (2023) SR-Unet: A Super-Resolution Algorithm for Ion Trap Mass Spectrometers Based on the Deep Neural Network. ANALYTICAL CHEMISTRY, 95 (47): (17407–17415). [PMID:37963290] [10.1021/acs.analchem.3c04172] |
| 2. Xi-Tian Peng, Bi-Feng Yuan, Yu-Qi Feng. (2011) Grafting of silica with a hydrophilic triol acrylamide polymer via surface-initiated “grafting from” method for hydrophilic-interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 34 (22): (3123-3130). [PMID:21998034] [10.1002/jssc.201100570] |
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