生物素-PEG4-酰肼

  • ≥94%
有货

库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
B304563-10mg
10mg 现货 Stock Image
B304563-50mg
50mg 现货 Stock Image
B304563-100mg
100mg 期货 Stock Image

基本描述

别名 N-[2-[2-[2-[2-(3-肼基-3-氧代丙氧基)乙氧基]乙氧基]乙氧基]乙基]生物素酰胺 | 15-(生物素酰氨基)-4,7,10,13-四氧杂十五烷酰肼
英文别名 N-[2-[2-[2-[2-(3-Hydrazinyl-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide | 15-(Biotinamido)-4,7,10,13-tetraoxapentadecanehydrazide
规格或纯度 ≥94%
英文名称 Biotin-PEG4-Hydrazide
生化机理 Biotin-dPEG4-hydrazide allows biotin labeling of molecules with free aldehydes or ketones. Biotin-dPEG4-hydrazide reacts to form a hydrazones. This reagent is highly useful for labeling carbohydrates, glycoproteins, and other molecules with biotin following oxidation of the carbohydrate or glycan with sodium periodate or by chemical installation of an aldehyde or ketone on the target molecule. The dPEG spacer is a single molecular weight PEG that provides excellent water solubility while extending the biotin moiety away from the surface of the labeled molecule for enhanced binding to avidin or streptavidin.
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

Biotin-PEG4-hydrazide 是一种生物素标记的 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

product description:

Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

名称和识别符

分子类型 未知
IUPAC Name N-[2-[2-[2-[2-(3-hydrazinyl-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
INCHI InChI=1S/C21H39N5O7S/c22-26-19(28)5-7-30-9-11-32-13-14-33-12-10-31-8-6-23-18(27)4-2-1-3-17-20-16(15-34-17)24-21(29)25-20/h16-17,20H,1-15,22H2,(H,23,27)(H,26,28)(H2,24,25,29)
InChi Key PSBJJOWIACLJAQ-UHFFFAOYSA-N
Canonical SMILES C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NN)NC(=O)N2
Isomeric SMILES C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NN)NC(=O)N2
PubChem CID 51340934
分子量 505.63

化学和物理性质

敏感性 对光&湿度&热敏感

安全和危险性(GHS)

RIDADR NONHforallmodesoftransport

质量标准

Appearance(B304563) White to yellow powder to crystal to solid
Purity(HPLC) 94-100(%)
Proton NMR spectrum Conforms to structure
LC-MS for identification Conforms

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 日期 货号
H2111158 分析证书 24-06-12 B304563
H2111164 分析证书 24-06-12 B304563
H2111170 分析证书 24-06-12 B304563

此产品的引用文献

1. Li Conghui, Yin Zhinang, Xiao Ruijing, Huang Beili, Cui Yali, Wang Honghong, Xiang Ying, Wang Lingrui, Lei Lingyu, Ye Jiaqin, Li Tianyu, Zhong Youquan, Guo Fangteng, Xia Yuchen, Fang Pingping, Liang Kaiwei.  (2022)  G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes.  GENOME BIOLOGY,  23  (1): (1-29).  [PMID:36522639] [10.1186/s13059-022-02830-8]

参考文献

1. Li Conghui, Yin Zhinang, Xiao Ruijing, Huang Beili, Cui Yali, Wang Honghong, Xiang Ying, Wang Lingrui, Lei Lingyu, Ye Jiaqin, Li Tianyu, Zhong Youquan, Guo Fangteng, Xia Yuchen, Fang Pingping, Liang Kaiwei.  (2022)  G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes.  GENOME BIOLOGY,  23  (1): (1-29).  [PMID:36522639] [10.1186/s13059-022-02830-8]

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