Recombinant CD19 Antibody (AF555)

    应用:
  • Flow Cytometry
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: P08D14
  • 偶联: AF555
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab224664-10T
10T 现货 Stock Image
Ab224664-25T
25T 现货 Stock Image
Ab224664-100T
100T 现货 Stock Image

基本信息

产品名称 Recombinant CD19 Antibody (AF555)
别名 白细胞分化抗原19 | B细胞抗原受体辅助受体 | CD19 抗体 | Anti-CD19抗体 | 小鼠抗人CD19抗体
英文别名 B4 | B-lymphocyte antigen CD19 | B-lymphocyte surface antigen B4 | CD19 antigen | CD19 molecule | CD19 | CVID3 | Differentiation antigen CD19 | Leu-12 | MGC12802 | T-cell surface antigen Leu-12 | Antibody deficiency due to defect in CD19 antibody | Antibo
规格或纯度 ExactAb™, 已验证, 重组, 5 μL/test
生化机理 Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
宿主种属 小鼠(Mouse)
特异性 Human CD19
种属反应性 人(Human)
免疫原 Human Chronic Lymphocytic Leukemia (CLL) Cells.
阳性对照 Flow Cytometry: Human peripheral blood lymphocytes; Raji cells
偶联 AF555
Excitation(nm) Green Laser(532nm)
Emission(nm) 568nm
Ex/Em(nm) Ex:553nm;Em:568nm

产品属性

克隆类型 重组抗体
Format Whole IgG
轻链亚型 kappa
纯化方法 Protein A purified
储存缓冲液 Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂 0.05% Proclin300
浓度 5 μL/test
储存温度 2-8°C储存,避光,禁止冷冻
运输条件 冰袋运输
稳定性与储存 The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型 抗体

关联靶点(人)

CD19 Tclin B淋巴细胞抗原CD19(B-lymphocyte antigen CD19) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

图片

Recombinant CD19 Antibody (AF555) (Ab224664) - Flow Cytometry
Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD19 Antibody (AF555) (Ab224664) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF555) (Ab190246).

Recombinant CD19 Antibody (AF555) (Ab224664) - Flow Cytometry
Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD19 Antibody (AF555) (Ab224664) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF555) (Ab190246). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称 稀释比例
Flow Cytometry

5μl/test

For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. 

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ25F0826095 分析证书 25-08-25 Ab224664
ZJ25F0826094 分析证书 25-08-25 Ab224664
ZJ25F0826093 分析证书 25-08-25 Ab224664

此产品的引用文献

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