Recombinant CD14 Antibody (AF750)

COA

级别和纯度:

重组

已验证

ExactAb™

5 μL/test

应用:

Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG2a
克隆号: P25A37
偶联: AF750

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货号 (SKU)	包装规格	是否现货
Ab223670-10T	10T	期货
Ab223670-25T	25T	期货
Ab223670-100T	100T	期货

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点击查看靶蛋白信息: CD14

Accession#:P08571 (61) AF750 (36) CD14 (65) Gene ID:929 (61)

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基本信息

产品名称	Recombinant CD14 Antibody (AF750)
规格或纯度	ExactAb™, 已验证, 重组, 5 μL/test
生化机理	Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
宿主种属	小鼠(Mouse)
特异性	Human CD14
种属反应性	人(Human)
免疫原	Full-length human CD14 protein
阳性对照	Flow Cytometry: Human peripheral blood monocytes
偶联	AF750
Excitation(nm)	Red Laser(633nm)
Emission(nm)	776nm
Ex/Em(nm)	Ex:752nm;Em:776nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

CD14 Tbio 单核细胞分化抗原CD14(Monocyte differentiation antigen CD14) (0 活性数据)

点击查看靶蛋白信息： CD14

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD14 Antibody (AF750) (Ab223670)

Recombinant CD14 Antibody (AF750) (Ab223670) - Flow Cytometry
Flow cytometry analysis of CD14 expression by human peripheral blood cells (right panel) compared to an isotype control (left panel). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD14 Antibody (AF750) (Ab223670) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF750) (Ab190249).

Flow Cytometry: Recombinant CD14 Antibody (AF750) (Ab223670)

Recombinant CD14 Antibody (AF750) (Ab223670) - Flow Cytometry
Flow cytometry analysis of CD14 expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD14 Antibody (AF750) (Ab223670) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF750) (Ab190249).

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Recombinant CD14 Antibody (AF750)

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基本信息

产品属性

关联靶点（人）

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

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