Recombinant CD15/SSEA-1 Antibody

    应用:
  • ELISA
  • Flow Cytometry
功能和特点
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: P52C45
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
Ab219623-10μg
10μg 期货 Stock Image
Ab219623-50μg
50μg 期货 Stock Image
Ab219623-100μg
100μg 期货 Stock Image
Ab219623-1mg
1mg 期货 Stock Image

基本信息

产品名称 Recombinant CD15/SSEA-1 Antibody
别名 阶段特异性胚胎抗原-1 | CD15抗体 | FUT4抗体 | Anti-CD15/SSEA-1抗体 | 小鼠抗人CD15抗体
英文别名 3)-fucosyltransferase antibody | Alpha-(1 antibody | Alpha-(1,3)-fucosyltransferase antibody | Alpha-3-fucosyltransferase antibody | ELAM-1 ligand fucosyltransferase antibody | ELFT antibody | FCT3A antibody | Fuc-TIV antibody | Fucosyltransferase 4 (Alph
规格或纯度 无动物源, 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 见COA
生化机理 Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis (By similarity). In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
宿主种属 小鼠(Mouse)
特异性 Human CD15
种属反应性 人(Human)
免疫原 WERI-RB-1 retinoblastoma cell line
阳性对照 Flow Cytometry: THP-1 cells
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
轻链亚型 kappa
纯化方法 Protein A purified
储存缓冲液 PBS, pH 6.0
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融。
分子类型 抗体

图片

Recombinant CD15/SSEA-1 Antibody (Ab219623) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling CD15/SSEA-1 (red) with Recombinant CD15/SSEA-1 Antibody (Ab219623) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Recombinant CD15/SSEA-1 Antibody (Ab219623) - SEC
The purity of Recombinant CD15/SSEA-1 Antibody (Ab219623) is more than 95% verified by HPLC.

关联靶点(人)

FUT4 Tbio α-(1,3)-岩藻糖基转移酶 4(Alpha-(1,3)-fucosyltransferase 4) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
Flow Cytometry

≤0.5 µg per million cells in 100 µl volume

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

溶液计算器