| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab219610-10μg |
10μg |
期货  |
| |
| Ab219610-50μg |
50μg |
期货 |
| |
| Ab219610-100μg |
100μg |
期货 |
| |
| Ab219610-1mg |
1mg |
期货 |
|
| 产品名称 | Recombinant CD14 Antibody |
|---|---|
| 别名 | MY23抗原 | LPS受体 | 细菌脂多糖膜受体 | CD14 抗体 | Anti-CD14抗体 | 小鼠抗人CD14抗体 |
| 英文别名 | CD14 antigen | CD14 molecule | CD14 | monocyte differentiation antigen CD14 | Myeloid cell-specific leucine-rich glycoprotein | CD 14 antibody | CD_antigen=CD14 antibody | CD14 antibody | CD14 antigen antibody | CD14 molecule antibody | CD14_HUMAN antibod |
| 规格或纯度 | 无动物源, 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 见COA |
| 生化机理 | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL. |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | Human CD14 |
| 种属反应性 | 人(Human) |
| 免疫原 | Human CD14 protein |
| 阳性对照 | Flow Cytometry: Human peripheral blood monocytes |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A purified |
| 储存缓冲液 | PBS, pH 6.0 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融. |
| 分子类型 | 抗体 |
Recombinant CD14 Antibody (Ab219610) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD14 with Recombinant CD14 Antibody (Ab219610) conjugated with biotin (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Mouse IgG (Ab170221) - Isotype Control (left panel) and detected with Alexa Fluor 488-conjugated affinipure goat anti-Mouse IgG.
Recombinant CD14 Antibody (Ab219610) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD14 (red) with Recombinant CD14 Antibody (Ab219610) conjugated with biotin at 0.2 μg/mL for 1 hour at 4°C, and detected with Alexa Fluor 488-conjugated affinipure goat anti-Mouse IgG. Blue - Isotype control, compared with Mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD14 Antibody (Ab219610) - SEC
The purity of Recombinant CD14 Antibody (Ab219610) is more than 95% verified by HPLC.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | ≤0.5 µg per million cells in 100 µl volume |
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