| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab213577-10μg |
10μg |
现货  |
| |
| Ab213577-25μg |
25μg |
现货 |
| |
| Ab213577-100μg |
100μg |
现货 |
|
| 产品名称 | MUC1/CD227 Mouse mAb (AF647) |
|---|---|
| 别名 | 粘蛋白1(MUC1)抗体 | MUC1/CD227抗体 |
| 英文别名 | MCD | PUM | MCKD | MCKD1 | ADMCKD | ADTKD2 | Ca15-3 | ADMCKD1 | CA 15-3 | MUC-1/X | MUC-1/SEC | Breast carcinoma-associated antigen DF3 | Carcinoma-associated mucin | CD227 antigen | CD227 | DF3 antigen | EMA | Episialin | H23 antigen | H23AG | KL-6 | MAM |
| 规格或纯度 | ExactAb™, 已验证, 0.5 mg/mL |
| 生化机理 | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | MUC1/CD227 |
| 种属反应性 | 人(Human) |
| 免疫原 | Purified human MUC1 |
| 阳性对照 | Flow Cytometry: MCF-7 |
| 偶联 | AF647 |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 668nm |
| Ex/Em(nm) | Ex:650nm;Em:668nm |
| 克隆类型 | 单克隆抗体 |
|---|---|
| Format | Whole IgG |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300. |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 0.5 mg/mL |
| 储存温度 | 2-8°C储存,避光,禁止冻结 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| 分子类型 | 抗体 |
MUC1/CD227 Mouse mAb (AF647) (Ab213577) - Flow Cytometry
Flow cytometry analysis of MUC1/CD227 expression by MCF-7 cells (red) compared to an isotype control (blue). Cells were stained with MUC1/CD227 Mouse mAb (AF647) (Ab213577) at 0.2μg/test for 1 hour at 4°C. Blue - Mouse IgG (AF647) (Ab190077). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | ≤1.0μg/ test For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume. |
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ25F0218276 |
分析证书 | 25-02-21 | Ab213577 |
| ZJ25F0218275 |
分析证书 | 25-02-21 | Ab213577 |
| ZJ25F0218274 |
分析证书 | 25-02-21 | Ab213577 |
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