| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab210008-10T |
10T |
现货  |
| |
| Ab210008-25T |
25T |
现货 |
| |
| Ab210008-100T |
100T |
现货 |
|
| 产品名称 | Transferrin Receptor/CD71 Mouse mAb (PE) |
|---|---|
| 别名 | 转铁蛋白受体(TFR)抗体 | Transferrin Receptor/CD71抗体 |
| 英文别名 | TFR | TRFR | IMD46 | CD71 antigen | CD71 | CD71TRFR | p90 | T9 | TfR (Transferrin R) | TfR (TransferrinR) | TFR1 | TFRC | TR | transferrin receptor (p90, CD71) | transferrin receptor protein 1 | CD 71 antibody | CD71 antibody | CD71 antigen antibody | IMD |
| 规格或纯度 | ExactAb™, 已验证, Ex:565nm, Em:575nm, 5 μL/test |
| 生化机理 | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240). (Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus. |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | Transferrin Receptor/CD71 |
| 种属反应性 | 人(Human) |
| 免疫原 | Human acute lymphoblastic leukemia cells |
| 阳性对照 | Flow: Jurkat |
| 偶联 | PE |
| Excitation(nm) | Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm) |
| Emission(nm) | 575nm |
| Ex/Em(nm) | Ex:565nm;Em:575nm |
| 克隆类型 | 单克隆抗体 |
|---|---|
| Format | Whole IgG |
| 纯化方法 | Protein G purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300. |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 5 μL/test |
| 储存温度 | 2-8°C储存,避光,禁止冻结 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| 分子类型 | 抗体 |
Transferrin Receptor/CD71 Mouse mAb (PE) (Ab210008) - Flow Cytometry
Flow cytometry analysis of Transferrin Receptor/CD71 expression by Jurkat cells (red) compared to an isotype control (blue). Cells were stained with Transferrin Receptor/CD71 Mouse mAb (PE) (Ab210008) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (PE) (Ab180308). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry |
5 μL/test,
the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood
|
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1214860 |
分析证书 | 24-12-05 | Ab210008 |
| ZJ24F1214859 |
分析证书 | 24-12-05 | Ab210008 |
| ZJ24F1214858 |
分析证书 | 24-12-05 | Ab210008 |
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