产品名称	Dalotuzumab (anti-IGF1R), 胰岛素样生长因子 I 受体拮抗剂
别名	达罗托组单抗 \| 达洛珠单抗（抗 IGF1R）
英文别名	CD221 antibody \| CD221 antigen antibody \| IGF 1 receptor antibody \| IGF 1R antibody \| IGF I receptor antibody \| IGF-I receptor antibody \| Igf1r antibody \| IGF1R_HUMAN antibody \| IGFIR antibody \| IGFIRC antibody \| IGFR antibody \| Insulin like growth factor
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	IGF1R
种属反应性	人(Human)
偶联	Unconjugated
作用类型	拮抗剂
作用机制	胰岛素样生长因子 I 受体拮抗剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	145 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	1005389-60-5
分子类型	抗体

图片

Flow Cytometry: Dalotuzumab (anti-IGF1R) (Ab183419)

Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Dalotuzumab (anti-IGF1R) (Ab183419)

Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Dalotuzumab (anti-IGF1R) (Ab183419)

Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Dalotuzumab (anti-IGF1R) (Ab183419)

Dalotuzumab (anti-IGF1R) (Ab183419) - SEC
The purity of Dalotuzumab (anti-IGF1R) (Ab183419) is more than 95% verified by HPLC.

ELISA: Dalotuzumab (anti-IGF1R) (Ab183419)

Dalotuzumab (anti-IGF1R) (Ab183419) - ELISA
Immobilized Recombinant Human AVItag His-IGF1R-Sino protein at 2.0 μg/mL can bind Dalotuzumab (anti-IGF1R) (Ab183419) with the EC50 of 1.09 ng/mL.

关联靶点（人）

IGF1R Tclin 胰岛素类生长因子 1 受体(Insulin-like growth factor 1 receptor) (0 活性数据)

点击查看靶蛋白信息： IGF1R