Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1)

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
功能和特点
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab177927-100μg
100μg 现货 Stock Image
Ab177927-1mg
1mg 现货 Stock Image
Ab177927-5mg
5mg 现货 Stock Image
Ab177927-10mg
10mg 期货 Stock Image

基本信息

产品名称 Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1)
别名 Asclepius Technology 专利抗Robo1 CAR(抗ROBO1)
英文别名 Deleted in U twenty twenty | H-Robo-1
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 ROBO1
种属反应性 人(Human)
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 25.6 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 194.9 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
物理外观 Liquid
储存缓冲液 Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

图片

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of U2OS cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - SEC
The purity of Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) is more than 95% verified by HPLC.

关联靶点(人)

ROBO1 Tbio 迂回同源物 1(Roundabout homolog 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

安全和危险性(GHS)

质量标准

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C of A & Other Certificates(BSE/TSE, COO):
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通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到6个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1114582 分析证书 24-11-29 Ab177927
ZJ24F1114583 分析证书 24-11-29 Ab177927
ZJ24F1114584 分析证书 24-11-29 Ab177927
ZJ24F0505087 分析证书 24-05-06 Ab177927
ZJ24F0505086 分析证书 24-05-06 Ab177927
ZJ24F0505085 分析证书 24-05-06 Ab177927

参考文献

1. Kidd, T T and 6 more authors..  (1998)  Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors..  Cell,  (23): [PMID:9458045]
2. Sundaresan, V V and 10 more authors..  (1998)  The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression..  Molecular and cellular neurosciences,  [PMID:9608531]
3. Sundaresan, V V and 18 more authors..  (1998)  Homozygous deletions at 3p12 in breast and lung cancer..  Oncogene,  (1): [PMID:9796701]
4. Brose, K K and 7 more authors..  (1999)  Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance..  Cell,  (19): [PMID:10102268]
5. Bashaw, G J GJ, Kidd, T T, Murray, D D, Pawson, T T and Goodman, C S CS..  (2000)  Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor..  Cell,  (23): [PMID:10892742]
6. Nguyen Ba-Charvet, K T KT and 7 more authors..  (2001)  Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  (15): [PMID:11404413]
7. Dallol, Ashraf A and 9 more authors..  (2002)  Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers..  Oncogene,  (2): [PMID:12082532]
8. Muzny, Donna M DM and 113 more authors..  (2006)  The DNA sequence, annotation and analysis of human chromosome 3..  Nature,  (27): [PMID:16641997]
9. Morlot, Cecile C and 7 more authors..  (2007)  Structural insights into the Slit-Robo complex..  Proceedings of the National Academy of Sciences of the United States of America,  (18): [PMID:17848514]
10. Zakrys, Linas L and 5 more authors..  (2014)  Roundabout 1 exists predominantly as a basal dimeric complex and this is unaffected by binding of the ligand Slit2..  The Biochemical journal,  (1): [PMID:24673457]
11. Kong, Ruirui R and 13 more authors..  (2015)  Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression..  The Journal of clinical investigation,  (3): [PMID:26529257]

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