MSC-1 (anti-LIF)

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
功能和特点
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human), 小鼠(Mouse), 食蟹猴(Cynomolgus monkey)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab177911-100μg
100μg 现货 Stock Image
Ab177911-1mg
1mg 现货 Stock Image
Ab177911-5mg
5mg 现货 Stock Image
Ab177911-10mg
10mg 期货 Stock Image

基本信息

产品名称 MSC-1 (anti-LIF)
别名 间充质干细胞-1(抗 LIF)
英文别名 D factor | Differentiation-stimulating factor | LIF | Melanoma-derived LPL inhibitor | MLPLI
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 LIF
种属反应性 人(Human),小鼠(Mouse),食蟹猴(Cynomolgus monkey)
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 26.5 kDa (Light Chain) & 49.9 kDa (Heavy Chain), under reducing conditions; 192.2 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

图片

MSC-1 (anti-LIF) (Ab177911) - ELISA
Immobilized huLIF at 2.0 μg/mL can bind MSC-1 (anti-LIF) (Ab177911) with the EC₅₀ of 119.5 ng/mL.


MSC-1 (anti-LIF) (Ab177911) - SEC
The purity of MSC-1 (anti-LIF) (Ab177911) is more than 95% verified by HPLC.

关联靶点(人)

LIF Tbio 白血病抑制因子(Leukemia inhibitory factor) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

安全和危险性(GHS)

质量标准

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到6个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1114508 分析证书 24-11-28 Ab177911
ZJ24F1114507 分析证书 24-11-28 Ab177911
ZJ24F1114506 分析证书 24-11-28 Ab177911
ZJ24F0404057 分析证书 24-04-02 Ab177911
ZJ24F0404056 分析证书 24-04-02 Ab177911
ZJ24F0404055 分析证书 24-04-02 Ab177911

参考文献

1. Stahl, J J and 5 more authors..  (1990)  Structural organization of the genes for murine and human leukemia inhibitory factor. Evolutionary conservation of coding and non-coding regions..  The Journal of biological chemistry,  (25): [PMID:1692837]
2. Lowe, D G DG and 9 more authors..  (1989)  Genomic cloning and heterologous expression of human differentiation-stimulating factor..  DNA (Mary Ann Liebert, Inc.),  [PMID:2475312]
3. Mori, M M, Yamaguchi, K K and Abe, K K..  (1989)  Purification of a lipoprotein lipase-inhibiting protein produced by a melanoma cell line associated with cancer cachexia..  Biochemical and biophysical research communications,  (15): [PMID:2730639]
4. Gough, N M NM and 6 more authors..  (1988)  Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor..  Proceedings of the National Academy of Sciences of the United States of America,  [PMID:3128791]
5. Moreau, J F JF and 5 more authors..  (1988)  Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells..  Nature,  (15): [PMID:3143918]
6. Schmelzer, C H CH and 5 more authors..  (1993)  Glycosylation pattern and disulfide assignments of recombinant human differentiation-stimulating factor..  Archives of biochemistry and biophysics,  [PMID:8489250]
7. Dunham, I I and 24 more authors..  (1999)  The DNA sequence of human chromosome 22..  Nature,  (2): [PMID:10591208]
8. Boulanger, Martin J MJ, Bankovich, Alexander J AJ, Kortemme, Tanja T, Baker, David D and Garcia, K Christopher KC..  (2003)  Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130..  Molecular cell,  [PMID:14527405]
9. Brandenberger, Ralph R and 13 more authors..  (2004)  Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation..  Nature biotechnology,  [PMID:15146197]
10. Huyton, Trevor T and 6 more authors..  (2007)  An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor..  Proceedings of the National Academy of Sciences of the United States of America,  (31): [PMID:17652170]

溶液计算器