| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab177903-100μg |
100μg |
现货  |
| |
| Ab177903-1mg |
1mg |
现货 |
| |
| Ab177903-5mg |
5mg |
现货 |
| |
| Ab177903-10mg |
10mg |
期货 |
|
| 产品名称 | CSL311 (anti-CSF2Rb) |
|---|---|
| 别名 | Beta-C antibody | CD131 antibody | CDw131 antibody | Colony stimulating factor 2 receptor beta antibody | Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) antibody | Common beta chain antibody | Csf2rb antibody | Cytokine re |
| 英文别名 | CDw131 | GM-CSF/IL-3/IL-5 receptor common beta subunit |
| 规格或纯度 | 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | CSF2RB |
| 种属反应性 | 人(Human) |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG4SP |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.0 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 182.4 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% (SDS-PAGE&SEC) |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
CSL311 (anti-CSF2Rb) (Ab177903) - Flow Cytometry
Flow Cytometry analysis of HepG2 cells labelling CSF2Rb (red) with CSL311 (anti-CSF2Rb) (Ab177903). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
CSL311 (anti-CSF2Rb) (Ab177903) - SEC
The purity of CSL311 (anti-CSF2Rb) (Ab177903) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1114060 |
分析证书 | 24-11-20 | Ab177903 |
| ZJ24F1114059 |
分析证书 | 24-11-20 | Ab177903 |
| ZJ24F1114058 |
分析证书 | 24-11-20 | Ab177903 |
| ZJ24F0404110 |
分析证书 | 24-04-03 | Ab177903 |
| ZJ24F0404111 |
分析证书 | 24-04-03 | Ab177903 |
| ZJ24F0404112 |
分析证书 | 24-04-03 | Ab177903 |
| 1. Morokata T, Ida K, Yamada T. (2002) Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.. Int Immunopharmacol, 2 (12): (1693-702). [PMID:12469943] |
| 2. Shen, Y Y and 6 more authors.. (1992) Localization of the human GM-CSF receptor beta chain gene (CSF2RB) to chromosome 22q12.2-->q13.1.. Cytogenetics and cell genetics, [PMID:1424804] |
| 3. Tavernier, J J and 5 more authors.. (1992) Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.. Proceedings of the National Academy of Sciences of the United States of America, (1): [PMID:1495999] |
| 4. Hayashida, K K and 5 more authors.. (1990) Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:1702217] |
| 5. Dirksen, U U and 6 more authors.. (1997) Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.. The Journal of clinical investigation, (1): [PMID:9410898] |
| 6. Ogata, N N and 6 more authors.. (1998) JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation.. Blood, (1): [PMID:9516124] |
| 7. Dunham, I I and 24 more authors.. (1999) The DNA sequence of human chromosome 22.. Nature, (2): [PMID:10591208] |
| 8. Mulhern, T D TD and 7 more authors.. (2000) The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5.. Journal of molecular biology, (7): [PMID:10736232] |
| 9. Rossjohn, J J and 7 more authors.. (2000) Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.. Blood, (15): [PMID:10753826] |
| 10. Carr, P D PD and 9 more authors.. (2001) Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.. Cell, (26): [PMID:11207369] |
| 11. Carr, P D PD, Conlan, F F, Ford, S S, Ollis, D L DL and Young, I G IG.. (2006) An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope.. Acta crystallographica. Section F, Structural biology and crystallization communications, (1): [PMID:16754968] |
| 12. Bhol, Kailash C KC and Schechter, Paul J PJ.. (2007) Effects of nanocrystalline silver (NPI 32101) in a rat model of ulcerative colitis.. Digestive diseases and sciences, [PMID:17436088] |
| 13. Kao, C-J CJ and 6 more authors.. (2008) CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.. Oncogene, (28): [PMID:17828305] |
| 14. Hansen, Guido G and 12 more authors.. (2008) The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.. Cell, (8): [PMID:18692472] |
| 15. Tanaka, Takeshi T and 13 more authors.. (2011) Adult-onset hereditary pulmonary alveolar proteinosis caused by a single-base deletion in CSF2RB.. Journal of medical genetics, [PMID:21075760] |
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