产品名称	ANX005 (anti-C1q)
别名	C1qa antibody \| C1QA_HUMAN antibody \| C1QB antibody \| C1QC antibody \| Complement C1q subcomponent subunit A antibody \| Complement C1q subcomponent subunit B antibody \| Complement C1q subcomponent subunit C antibody \| Complement component 1 q subcomponent
英文别名	C1qa antibody \| C1QA_HUMAN antibody \| C1QB antibody \| C1QC antibody \| Complement C1q subcomponent subunit A antibody \| Complement C1q subcomponent subunit B antibody \| Complement C1q subcomponent subunit C antibody \| Complement component 1 q subcomponent
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	C1QA
种属反应性	人(Human),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	27.3 kDa (Light Chain) & 55.1 kDa (Heavy Chain), under reducing conditions; 193.6 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

图片

SEC: ANX005 (anti-C1q) (Ab177901)

ANX005 (anti-C1q) (Ab177901) - SEC
The purity of ANX005 (anti-C1q) (Ab177901) is more than 95% verified by HPLC.

ELISA: ANX005 (anti-C1q) (Ab177901)

ANX005 (anti-C1q) (Ab177901) - ELISA
Immobilized Human C1Q Protein at 2.0 μg/mL can bind ANX005 (anti-C1q) (Ab177901) with the EC₅₀ of 21.11 ng/mL.

关联靶点（人）

C1QA Tbio 补体 C1q 亚成分亚基 A(Complement C1q subcomponent subunit A) (0 活性数据)

点击查看靶蛋白信息： C1QA

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F0303103	分析证书	24-03-08	Ab177901
ZJ24F0303104	分析证书	24-03-08	Ab177901
ZJ24F0303105	分析证书	24-03-08	Ab177901

参考文献

1. and Reid, K B KB.. (1979) Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement.. The Biochemical journal, (1): [PMID:486087]
2. Sellar, G C GC, Blake, D J DJ and Reid, K B KB.. (1991) Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q.. The Biochemical journal, (1): [PMID:1706597]
3. Reid, K B KB, Gagnon, J J and Frampton, J J.. (1982) Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement.. The Biochemical journal, (1): [PMID:6981411]
4. and Petry, F F.. (1998) Molecular basis of hereditary C1q deficiency.. Immunobiology, [PMID:9777412]
5. Gaboriaud, Christine C and 8 more authors.. (2003) The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties.. The Journal of biological chemistry, (21): [PMID:12960167]
6. Wang, Yaning Y, Fei, David D, Vanderlaan, Martin M and Song, An A.. (2004) Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro.. Angiogenesis, [PMID:15886877]
7. Kang, Mingsong M and 6 more authors.. (2013) Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway.. The Journal of biological chemistry, (12): [PMID:23720782]
8. Son, Myoungsun M and 5 more authors.. (2017) Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression.. Scientific reports, (21): [PMID:28325905]
9. Deveuve, Quentin; Lajoie, Laurie; Barrault, Benjamin and Thibault, Gilles.. (2020) The Proteolytic Cleavage of Therapeutic Monoclonal Antibody Hinge Region: More Than a Matter of Subclass.. Frontiers in immunology, [PMID:32117299]

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ANX005 (anti-C1q)

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基本信息

产品属性

图片

关联靶点（人）

安全和危险性（GHS）

质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

参考文献

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