| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab177869-100μg |
100μg |
现货  |
| |
| Ab177869-1mg |
1mg |
现货 |
| |
| Ab177869-5mg |
5mg |
现货 |
| |
| Ab177869-10mg |
10mg |
期货 |
|
| 产品名称 | Icatolimab (anti-BTLA) |
|---|---|
| 别名 | 艾卡托利单抗(抗 BTLA) |
| 英文别名 | B- and T-lymphocyte-associated protein |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | BTLA |
| 种属反应性 | 人(Human),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG4SP |
| 轻链亚型 | kappa |
| SDS-PAGE | 146 kDa |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
Icatolimab (anti-BTLA) (Ab177869) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA with Icatolimab (anti-BTLA) (Ab177869) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Icatolimab (anti-BTLA) (Ab177869) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA (red) with Icatolimab (anti-BTLA) (Ab177869) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Icatolimab (anti-BTLA) (Ab177869) - SEC
The purity of Icatolimab (anti-BTLA) (Ab177869) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1214836 |
分析证书 | 24-12-05 | Ab177869 |
| ZJ24F1214835 |
分析证书 | 24-12-05 | Ab177869 |
| ZJ24F1214834 |
分析证书 | 24-12-05 | Ab177869 |
| ZJ23F1201944 |
分析证书 | 23-12-06 | Ab177869 |
| ZJ23F1201945 |
分析证书 | 23-12-06 | Ab177869 |
¥579.90
| 1. Watanabe, Norihiko N and 13 more authors.. (2003) BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.. Nature immunology, [PMID:12796776] |
| 2. Gavrieli, Maya M, Watanabe, Norihiko N, Loftin, Susan K SK, Murphy, Theresa L TL and Murphy, Kenneth M KM.. (2003) Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2.. Biochemical and biophysical research communications, (26): [PMID:14652006] |
| 3. Sedy, John R JR and 10 more authors.. (2005) B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.. Nature immunology, [PMID:15568026] |
| 4. Compaan, Deanne M DM and 5 more authors.. (2005) Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex.. The Journal of biological chemistry, (25): [PMID:16169851] |
| 5. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997] |
| 6. Cai, Guifang G and 5 more authors.. (2008) CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator.. Nature immunology, [PMID:18193050] |
| 7. Cheung, Timothy C TC and 12 more authors.. (2009) T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:19915044] |
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