计算溶液所需的质量、体积或浓度。
Polatuzumab (anti-CD79b) (Ab175715) - ELISA
Immobilized hu-CD79b-His at 2 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC₅₀ of 4.09 ng/mL.
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab175715-100μg |
100μg |
现货 ![]() |
| |
| Ab175715-1mg |
1mg |
现货 ![]() |
| |
| Ab175715-5mg |
5mg |
现货 ![]() |
| |
| Ab175715-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Polatuzumab (anti-CD79b) |
|---|---|
| 别名 | 泊洛妥珠单抗 | 波拉珠单抗(抗 CD79b) |
| 英文别名 | AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein B29 antibody | B-cell antigen receptor complex-associated protein beta chain antibody | B-cell-specific glycoprotein B29 antibody | B29 a |
| 规格或纯度 | 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | CD79B |
| 种属反应性 | 人(Human),小鼠(Mouse),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 27.4 kDa (Light Chain) & 51.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% (SDS-PAGE&SEC) |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 2279068-37-8 |
| 分子类型 | 抗体 |
Polatuzumab (anti-CD79b) (Ab175715) - ELISA
Immobilized hu-CD79b-His at 2 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC₅₀ of 4.09 ng/mL.
Polatuzumab (anti-CD79b) (Ab175715) - SEC
The purity of Polatuzumab (anti-CD79b) (Ab175715) is more than 95% verified by HPLC.
Recombinant Human CD79B Protein (rp176729) - ELISA
Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
| 分析证书 | 24-03-08 | Ab175715 | |
| 分析证书 | 24-03-08 | Ab175715 | |
| 分析证书 | 24-03-08 | Ab175715 |
| 1. Müller, B B, Cooper, L L and Terhorst, C C.. (1992) Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29.. European journal of immunology, [PMID:1534761] |
| 2. Vasile, S S, Coligan, J E JE, Yoshida, M M and Seon, B K BK.. (1994) Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex.. Molecular immunology, [PMID:7514267] |
| 3. Hashimoto, S S, Chiorazzi, N N and Gregersen, P K PK.. (1995) Alternative splicing of CD79a (Ig-alpha/mb-1) and CD79b (Ig-beta/B29) RNA transcripts in human B cells.. Molecular immunology, [PMID:7643857] |
| 4. Hashimoto, S S, Chiorazzi, N N and Gregersen, P K PK.. (1994) The complete sequence of the human CD79b (Ig beta/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism.. Immunogenetics, [PMID:7913081] |
| 5. Hashimoto, S S, Gregersen, P K PK and Chiorazzi, N N.. (1993) The human Ig-beta cDNA sequence, a homologue of murine B29, is identical in B cell and plasma cell lines producing all the human Ig isotypes.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:8419481] |
| 6. Wood, W J WJ and 6 more authors.. (1993) Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB).. Genomics, [PMID:8486355] |
| 7. Dobbs, A Kerry and 5 more authors.. (2007) Cutting edge: a hypomorphic mutation in Igbeta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:17675462] |