| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab175695-100μg |
100μg |
现货  |
| |
| Ab175695-1mg |
1mg |
现货 |
| |
| Ab175695-5mg |
5mg |
现货 |
| |
| Ab175695-10mg |
10mg |
期货 |
|
| 产品名称 | Vantictumab (anti-FZD), FZD 1 抗体;FZD 2 抗体;FZD 5 抗体;FZD 7 抗体;FZD 8 抗体 |
|---|---|
| 别名 | 万替妥单抗 | 万妥珠单抗（抗 FZD） |
| 英文别名 | Anti-FZD Reference Antibody | OMP-18R5 | C2orf31 antibody | DKFZP434E2135 antibody | Frizzled 5 seven transmembrane spanning receptor antibody | Frizzled class receptor 5 antibody | Frizzled family receptor 5 antibody | Frizzled homolog 5 antibody | Frizz |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | FZD |
| 种属反应性 | 人(Human) |
| 偶联 | Unconjugated |
| 作用类型 | 拮抗剂 |
| 作用机制 | FZD 1 抗体;FZD 2 抗体;FZD 5 抗体;FZD 7 抗体;FZD 8 抗体 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG2 |
| 轻链亚型 | lambda |
| SDS-PAGE | 143.16 kDa |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 1345009-45-1 |
| 分子类型 | 抗体 |
Vantictumab (anti-FZD) (Ab175695) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling FZD (red) with Vantictumab (anti-FZD) (Ab175695). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vantictumab (anti-FZD) (Ab175695) - SEC
The purity of Vantictumab (anti-FZD) (Ab175695) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1214794 |
分析证书 | 24-12-04 | Ab175695 |
| ZJ24F1214793 |
分析证书 | 24-12-04 | Ab175695 |
| ZJ24F1214792 |
分析证书 | 24-12-04 | Ab175695 |
| 1. Katoh M, Katoh M. (2007) WNT signaling pathway and stem cell signaling network.. Clin Cancer Res, 13 (14): (4042-5). [PMID:17634527] |
| 2. Gurney A, Axelrod F, Bond CJ, Cain J, Chartier C, Donigan L, Fischer M, Chaudhari A, Ji M, Kapoun AM et al.. (2012) Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.. Proc Natl Acad Sci USA, 109 (29): (11717-22). [PMID:22753465] |
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