| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab175581-100μg |
100μg |
现货  |
| |
| Ab175581-1mg |
1mg |
现货 |
| |
| Ab175581-5mg |
5mg |
现货 |
| |
| Ab175581-10mg |
10mg |
期货 |
|
| 产品名称 | Lintuzumab (anti-CD33), CD33 抗体 |
|---|---|
| 别名 | 林妥珠单抗 | 林妥珠单抗（抗 CD33） |
| 英文别名 | CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33_HUMAN antibody | FLJ00391 antibody | gp67 antibody | My9 antibody | Myeloid cell surface antigen CD33 antibody | Myeloid differentiation |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | CD33 |
| 种属反应性 | 人(Human) |
| 偶联 | Unconjugated |
| 作用类型 | 其它 |
| 作用机制 | CD33 抗体 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 145.24 kDa |
| 纯化方法 | Protein A purified |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH5.0. |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS编号和信息 | 166089-32-3 |
| 分子类型 | 抗体 |
Lintuzumab (anti-CD33) (Ab175581) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 with Lintuzumab (anti-CD33) (Ab175581) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Lintuzumab (anti-CD33) (Ab175581) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 (red) with Lintuzumab (anti-CD33) (Ab175581) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Lintuzumab (anti-CD33) (Ab175581) - SEC
The purity of Lintuzumab (anti-CD33) (Ab175581) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0708647 |
分析证书 | 24-07-24 | Ab175581 |
| ZJ24F0708646 |
分析证书 | 24-07-24 | Ab175581 |
| ZJ24F0708645 |
分析证书 | 24-07-24 | Ab175581 |
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| 1. Taylor VC, Buckley CD, Douglas M, Cody AJ, Simmons DL, Freeman SD. (1999) The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.. J Biol Chem, 274 (17): (11505-12). [PMID:10206955] |
| 2. Ulyanova T, Blasioli J, Woodford-Thomas TA, Thomas ML. (1999) The sialoadhesin CD33 is a myeloid-specific inhibitory receptor.. Eur J Immunol, 29 (11): (3440-9). [PMID:10556798] |
| 3. Ferlazzo G, Spaggiari GM, Semino C, Melioli G, Moretta L. (2000) Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors.. Eur J Immunol, 30 (3): (827-33). [PMID:10741398] |
| 4. Paul SP, Taylor LS, Stansbury EK, McVicar DW. (2000) Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.. Blood, 96 (2): (483-90). [PMID:10887109] |
| 5. Caron PC, Co MS, Bull MK, Avdalovic NM, Queen C, Scheinberg DA. (1992) Biological and immunological features of humanized M195 (anti-CD33) monoclonal antibodies.. Cancer Res, 52 (24): (6761-7). [PMID:1458463] |
| 6. Garnache-Ottou F, Chaperot L, Biichle S, Ferrand C, Remy-Martin JP, Deconinck E, de Tailly PD, Bulabois B, Poulet J, Kuhlein E et al.. (2005) Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells.. Blood, 105 (3): (1256-64). [PMID:15388576] |
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