产品名称	Enokizumab (anti-IL-9), 白细胞介素-9 抑制剂
别名	依诺凯组单抗 \| 伊诺单抗（抗IL-9）
英文别名	Cytokine P40 antibody \| Homolog of mouse T cell and mast cell growth factor 40 antibody \| HP40 antibody \| IL 9 antibody \| IL-9 antibody \| Il9 antibody \| IL9_HUMAN antibody \| Interleukin 9 antibody \| Interleukin-9 antibody \| Mast cell growth factor antibod
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	IL9
种属反应性	人(Human)
偶联	Unconjugated
作用类型	抑制剂
作用机制	白细胞介素-9 抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	27.5 kDa (Light Chain) & 54.2 kDa (Heavy Chain), under reducing conditions; 179.0 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	909875-08-7
分子类型	抗体

图片

ELISA: Enokizumab (anti-IL-9) (Ab175530)

Enokizumab (anti-IL-9) (Ab175530) - ELISA
Immobilized Recombinant Human IL-9 Protein (rp147650) at 1.0 μg/mL can bind Enokizumab (anti-IL-9) (Ab175530) with the EC₅₀ of 487.9 ng/mL.

SEC: Enokizumab (anti-IL-9) (Ab175530)

Enokizumab (anti-IL-9) (Ab175530) - SEC
The purity of Enokizumab (anti-IL-9) (Ab175530) is more than 95% verified by HPLC.

关联靶点（人）

IL9 Tbio 白细胞介素-9(Interleukin-9) (0 活性数据)

点击查看靶蛋白信息： IL9

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

安全和危险性（GHS）

SDS英文版

质量标准

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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到5个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F0911534	分析证书	24-09-30	Ab175530
ZJ24F0911533	分析证书	24-09-30	Ab175530
ZJ24F0911532	分析证书	24-09-30	Ab175530
ZJ23F1101608	分析证书	23-11-08	Ab175530
ZJ23F1101609	分析证书	23-11-08	Ab175530

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参考文献

1. White B, Leon F, White W, Robbie G. (2009) Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers.. Clin Ther, 31 (4): (728-40). [PMID:19446146]
2. Parker JM, Oh CK, LaForce C, Miller SD, Pearlman DS, Le C, Robbie GJ, White WI, White B, Molfino NA et al.. (2011) Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.. BMC Pulm Med, 11 (14). [PMID:21356110]
3. Oh CK, Raible D, Geba GP, Molfino NA. (2011) Biology of the interleukin-9 pathway and its therapeutic potential for the treatment of asthma.. Inflamm Allergy Drug Targets, 10 (3): (180-6). [PMID:21428906]
4. Gong F, Pan YH, Huang X, Zhu HY, Jiang DL. (2017) From bench to bedside: Therapeutic potential of interleukin-9 in the treatment of asthma.. Exp Ther Med, 13 (2): (389-394). [PMID:28352305]
5. Oh CK, Leigh R, McLaurin KK, Kim K, Hultquist M, Molfino NA. (2013) A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma.. Respir Res, 14 (93). [PMID:24050312]
6. Kelleher, K K and 8 more authors.. (1991) Human interleukin-9: genomic sequence, chromosomal location, and sequences essential for its expression in human T-cell leukemia virus (HTLV)-I-transformed human T cells.. Blood, (1): [PMID:1901233]
7. Renauld, J C JC and 5 more authors.. (1990) Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:1971295]
8. Renauld, J C JC, Goethals, A A, Houssiau, F F, Van Roost, E E and Van Snick, J J.. (1990) Cloning and expression of a cDNA for the human homolog of mouse T cell and mast cell growth factor P40.. Cytokine, [PMID:2129501]
9. Yang, Y C YC and 5 more authors.. (1989) Expression cloning of cDNA encoding a novel human hematopoietic growth factor: human homologue of murine T-cell growth factor P40.. Blood, (1): [PMID:2508790]
10. Renga, Giorgia and 18 more authors.. (2018) IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut.. Cell reports, (8): [PMID:29742432]

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Enokizumab (anti-IL-9), 白细胞介素-9 抑制剂

库存信息

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基本信息

产品属性

图片

关联靶点（人）

作用机制

安全和危险性（GHS）

质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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参考文献

溶液计算器

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