Otelixizumab (anti-CD3), CD3e 抗体

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
功能和特点
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
Ab170522-100μg
100μg 现货 Stock Image
Ab170522-1mg
1mg 现货 Stock Image
Ab170522-5mg
5mg 现货 Stock Image
Ab170522-10mg
10mg 期货 Stock Image

基本信息

产品名称 Otelixizumab (anti-CD3), CD3e 抗体
别名 奥昔组单抗 | 奥替利珠单抗(抗 CD3)
英文别名 Anti-CD3 Reference Antibody (otelixizumab) | Otelixizumab | ChAglyCD3 | TRX 4 | 4930549J05Rik antibody | A430104F18Rik antibody | AW552088 antibody | Cd247 antibody | CD247 antigen antibody | CD247 antigen, zeta subunit antibody | CD247 molecule antibody
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 CD3D
应用 ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
种属反应性 人(Human)
偶联 Unconjugated
作用类型 结合剂
作用机制 CD3e 抗体

产品属性

抗体类型 Primary antibody
克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 lambdaC2
SDS-PAGE 27.0 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 181.4 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
来源 CHO supernatant
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 881191-44-2
分子类型 抗体

图片

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with Otelixizumab (anti-CD3) (Ab170522) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with Otelixizumab (anti-CD3) (Ab170522) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Otelixizumab (anti-CD3) (Ab170522). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Otelixizumab (anti-CD3) (Ab170522) - SEC
The purity of Otelixizumab (anti-CD3) (Ab170522) is more than 95% verified by HPLC.

关联靶点(人)

CD3D Tclin T 细胞表面糖蛋白 CD3 δ 链(T-cell surface glycoprotein CD3 delta chain) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CD3E Tclin 细胞表面糖蛋白 CD3 ε 链(T-cell surface glycoprotein CD3 epsilon chain) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

质量标准

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到4个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1012830 分析证书 24-10-24 Ab170522
ZJ24F1012829 分析证书 24-10-24 Ab170522
ZJ24F1012828 分析证书 24-10-24 Ab170522
ZJ23F1001497 分析证书 23-11-02 Ab170522

参考文献

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17. Jin, Pei P and 7 more authors..  (2004)  PCR isolation and cloning of novel splice variant mRNAs from known drug target genes..  Genomics,  [PMID:15028279]
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