计算溶液所需的质量、体积或浓度。
Vibostolimab (anti-TIGIT) (Ab169311) - ELISA
Immobilized Human-TIGIT-ECD-his at 2 μg/mL can bind Vibostolimab (anti-TIGIT) (Ab169311) with the EC₅₀ of 18.61 ng/mL.
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab169311-100μg |
100μg |
现货 ![]() |
| |
| Ab169311-1mg |
1mg |
现货 ![]() |
| |
| Ab169311-5mg |
5mg |
现货 ![]() |
| |
| Ab169311-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Vibostolimab (anti-TIGIT), 具有 Ig 和 ITIM 结构域的 T 细胞免疫受体拮抗剂 |
|---|---|
| 别名 | 维博利单抗 | 维博斯托利单抗(抗 TIGIT) |
| 英文别名 | MK-7684 | Vibostolimab | DKFZp667A205 antibody | ENSMUSG00000071552 antibody | FLJ39873 antibody | RGD1563191 antibody | T cell immunoreceptor with Ig and ITIM domains antibody | TIGIT antibody | TIGIT_HUMAN antibody | V-set and immunoglobulin domain cont |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | TIGIT |
| 应用 | Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) |
| 种属反应性 | 人(Human),恒河猴(Rhesus monkey),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 作用类型 | 拮抗剂 |
| 作用机制 | 具有 Ig 和 ITIM 结构域的 T 细胞免疫受体拮抗剂 |
| 抗体类型 | Primary antibody |
|---|---|
| 克隆类型 | 重组抗体 |
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 27.2 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 181.7 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 来源 | CHO supernatant |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-AC, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 2231305-30-7 |
| 分子类型 | 抗体 |
Vibostolimab (anti-TIGIT) (Ab169311) - ELISA
Immobilized Human-TIGIT-ECD-his at 2 μg/mL can bind Vibostolimab (anti-TIGIT) (Ab169311) with the EC₅₀ of 18.61 ng/mL.
Vibostolimab (anti-TIGIT) (Ab169311) - SEC
The purity of Vibostolimab (anti-TIGIT) (Ab169311) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
| 分析证书 | 24-09-29 | Ab169311 | |
| 分析证书 | 24-09-29 | Ab169311 | |
| 分析证书 | 24-09-29 | Ab169311 | |
| 分析证书 | 23-10-26 | Ab169311 | |
| 分析证书 | 23-10-26 | Ab169311 |
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| 1. Yu X, Harden K, Gonzalez LC, Francesco M, Chiang E, Irving B, Tom I, Ivelja S, Refino CJ, Clark H et al.. (2009) The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.. Nat Immunol, 10 (1): (48-57). [PMID:19011627] |
| 2. Stengel, Katharina F KF and 9 more authors.. (2012) Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.. Proceedings of the National Academy of Sciences of the United States of America, (3): [PMID:22421438] |