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VDAC1/Porin Antibody

COA COA
    应用:
  • IF/ICC
  • IHC
  • WB
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab133998-10μl
 10μl 现货 Stock Image
Ab133998-50μl
 50μL 现货 Stock Image
Ab133998-100μl
 100μL 现货 Stock Image
Ab133998-1ml
 1ml 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
点击查看靶蛋白信息: VDAC1
Accession#:P21796 (1) Gene ID:7416 (1) Porin (1) VDAC1 (1)
main product photo

基本信息

产品名称 VDAC1/Porin Antibody
别名 电压依赖性阴离子通道蛋白1抗体 | 电压依赖性阴离子通道蛋白1单克隆抗体 | 电压依赖性阴离子通道蛋白1重组单克隆抗体 | VDAC1抗体 | VDAC1单克隆抗体 | VDAC1重组单克隆抗体 | Porin抗体 | Porin单克隆抗体 | Porin重组单克隆抗体
英文别名 N2441 antibody | OMP2 antibody | POR1 antibody | hVDAC1 antibody | MGC111064 antibody | Mitochondrial Porin antibody | Outer mitochondrial membrane protein porin 1 antibody | Plasmalemmal porin antibody | Porin 31HL antibody | Porin 31HM antibody | VDAC a
规格或纯度 ExactAb™, 已验证, 重组, 见COA
生化机理 Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
宿主种属 兔(Rabbit)
特异性 VDAC1/Porin
种属反应性 人(Human),大鼠(Rat),小鼠(Mouse)
免疫原 A synthetic peptide derived from human VDAC1 (AA 1-66).
阳性对照 WB: Raji, HEK293, A431, HeLa, THP-1, Jurkat, Hep G2, NIH/3T3 and C6 cell lysates. IHC: Human liver, stomach, prostate cancer, Mouse intestine, skin tissue. IF/ICC: HeLa cells.
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Rabbit IgG
轻链亚型 kappa
SDS-PAGE 150 kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂 0.02% Sodium azide
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

关联靶点（人）

VDAC1 Tbio 电压依赖性阴离子选择性通道蛋白 1(Voltage-dependent anion-selective channel protein 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

VDAC1/Porin Antibody (Ab133998) - Western Blot
All lanes: VDAC1/Porin Antibody (Ab133998) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 31 kDa
Observed band size: 31 kDa
Exposure time: 16.3 s

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1/Porin Antibody (Ab133998). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemical analysis of paraffin-embedded Mouse intestine, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemical analysis of paraffin-embedded Mouse skin, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemical analysis of paraffin-embedded Human stomach, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.

VDAC1/Porin Antibody (Ab133998) - IF/ICC
Immunofluorescent analysis of HeLa cells, using VDAC1/Porin Antibody (Ab133998) at 1/50 dilution.

应用

应用名称 稀释比例
IF/ICC

1/50-1/200

IHC

1/100 - 1/200
WB

1/1000 - 1/2000

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number) 证书类型 日期 货号
ZJ25F0420601 分析证书 25-04-18 Ab133998
ZJ25F0420600 分析证书 25-04-18 Ab133998
ZJ25F0420599 分析证书 25-04-18 Ab133998
ZJ25F0319536 分析证书 25-03-20 Ab133998
ZJ24F0202794 分析证书 24-02-23 Ab133998
ZJ24F0202793 分析证书 24-02-23 Ab133998

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引用文献

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