| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab109269-10μg |
10μg |
现货  |
| |
| Ab109269-50μg |
50μg |
现货 |
| |
| Ab109269-100μg |
100μg |
现货 |
| |
| Ab109269-1mg |
1mg |
期货 |
|
| 产品名称 | CD278/ICOS Armenian Hamster mAb |
|---|---|
| 别名 | 诱导协同刺激分子CD278抗体 | CD278抗体 | Anti-CD278抗体 | CD278/ICOS 亚美尼亚仓鼠 mAb |
| 英文别名 | Activation-inducible lymphocyte immunomediatory molecule | AILIM | AILIMCD278 | CD278 antigen | CD278 | CRP-1 | CVID1 | ICOS | inducible costimulator | inducible T-cell costimulator | inducible T-cell co-stimulator | MGC39850 | Activation inducible lympho |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 亚美尼亚仓鼠(Armenian hamster) |
| 特异性 | ICOS |
| 种属反应性 | 人(Human),大鼠(Rat),小鼠(Mouse) |
| 免疫原 | Mouse T cell clone D10.G4.1 |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | C398.4A |
| Format | Whole IgG |
| 亚型 | Armenian Hamster IgG |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, pH 7.2-7.4 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。 |
| 分子类型 | 抗体 |
CD278/ICOS Armenian Hamster mAb (Ab109269) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling CD278/ICOS (red) with CD278/ICOS Armenian Hamster mAb (Ab109269) conjugated with biotin at 5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | 1μg/100w cells |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0505799 |
分析证书 | 25-02-25 | Ab109269 |
| ZJ24F0505797 |
分析证书 | 25-02-25 | Ab109269 |
| ZJ24F0505798 |
分析证书 | 25-02-25 | Ab109269 |
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| 1. Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Kraft R, Anagnostopoulos I, Kroczek RA. (1999) ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.. Nature, 397 (6716): (263-6). [PMID:9930702] |
| 2. Beier KC, Hutloff A, Dittrich AM, Heuck C, Rauch A, Büchner K, Ludewig B, Ochs HD, Mages HW, Kroczek RA. (2000) Induction, binding specificity and function of human ICOS.. Eur J Immunol, 30 (12): (3707-17). [PMID:11169414] |
| 3. Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Dräger R, Eibel H, Fischer B, Schäffer AA, Mages HW et al.. (2003) Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency.. Nat Immunol, 4 (3): (261-8). [PMID:12577056] |
| 4. Aicher, A A and 8 more authors.. (2000) Characterization of human inducible costimulator ligand expression and function.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:10779774] |
| 5. Tezuka, K K and 6 more authors.. (2000) Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulatory molecule, related to the CD28/CTLA4 family.. Biochemical and biophysical research communications, (16): [PMID:11006126] |
| 6. Ling, V V and 9 more authors.. (2001) Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches.. Genomics, [PMID:11735222] |
| 7. Haaning Andersen, A D AD, Lange, M M and Lillevang, S T ST.. (2003) Allelic variation of the inducible costimulator (ICOS) gene: detection of polymorphisms, analysis of the promoter region, and extended haplotype estimation.. Tissue antigens, [PMID:12753665] |
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