DTX3L Antibody

    应用:
  • WB
功能和特点
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
Ab100564-10μl
10μl 现货 Stock Image
Ab100564-50μl
50μL 现货 Stock Image
Ab100564-100μl
100μL 期货 Stock Image
Ab100564-1ml
1ml 期货 Stock Image

基本信息

产品名称 DTX3L Antibody
别名 DTX3L蛋白抗体 | DTX3L 抗体
英文别名 BBAP | RNF143 | B lymphoma and BAL associated protein antibody | B-lymphoma- and BAL-associated protein antibody | BBAP antibody | Deltex 3 like antibody | DTX 3L antibody | DTX3L antibody | DTX3L_HUMAN antibody | E3 ubiquitin-protein ligase DTX3L antibod
规格或纯度 ExactAb™, Validated, Carrier Free, 0.5 mg/mL
宿主种属 兔(Rabbit)
特异性 DTX3L
种属反应性 人(Human)
免疫原 Fusion protein of human DTX3L (AA 207-332).
阳性对照 WB: HT-29 and MCF7 cell lysates.
偶联 Unconjugated

产品属性

克隆类型 多克隆抗体
Format Whole IgG
亚型 Rabbit IgG
SDS-PAGE 150 kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4
防腐剂 0.05% Sodium azide
浓度 0.5 mg/mL
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

图片

DTX3L Antibody (Ab100564) - Western Blot
All lanes: DTX3L Antibody (Ab100564) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 84 kDa
Observed band size: 81 kDa
Exposure time: 10.0 s

DTX3L Antibody (Ab100564) - Western Blot
All lanes: DTX3L Antibody (Ab100564) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 84 kDa
Observed band size: 81 kDa
Exposure time: 96.2 s

关联靶点(人)

DTX3L Tbio E3 泛素蛋白连接酶 DTX3L(E3 ubiquitin-protein ligase DTX3L) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
WB

1/500-1/2000

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到2个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0102413 分析证书 24-01-10 Ab100564
ZJ24F0102414 分析证书 24-01-10 Ab100564

参考文献

1. Takeyama, Kunihiko K and 7 more authors..  (2003)  The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity..  The Journal of biological chemistry,  (13): [PMID:12670957]
2. Juszczynski, Przemyslaw P and 5 more authors..  (2006)  BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate..  Molecular and cellular biology,  [PMID:16809771]
3. Sjöblom, Tobias T and 28 more authors..  (2006)  The consensus coding sequences of human breast and colorectal cancers..  Science (New York, N.Y.),  (13): [PMID:16959974]
4. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP..  (2006)  A probability-based approach for high-throughput protein phosphorylation analysis and site localization..  Nature biotechnology,  [PMID:16964243]
5. Dephoure, Noah N and 6 more authors..  (2008)  A quantitative atlas of mitotic phosphorylation..  Proceedings of the National Academy of Sciences of the United States of America,  (5): [PMID:18669648]
6. Daub, Henrik H and 9 more authors..  (2008)  Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle..  Molecular cell,  (8): [PMID:18691976]
7. Yan, Qingsheng Q and 6 more authors..  (2009)  BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response..  Molecular cell,  (9): [PMID:19818714]
8. Obiero, Josiah J, Walker, John R JR and Dhe-Paganon, Sirano S..  (2012)  Fold of the conserved DTC domain in Deltex proteins..  Proteins,  [PMID:22411408]
9. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,  (4): [PMID:23186163]
10. Yan, Qingsheng Q and 6 more authors..  (2013)  BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8..  Molecular and cellular biology,  [PMID:23230272]
11. Holleman, Justine J and Marchese, Adriano A..  (2014)  The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4..  Molecular biology of the cell,  (15): [PMID:24790097]
12. Zhang, Yong Y and 18 more authors..  (2015)  PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection..  Nature immunology,  [PMID:26479788]
13. Yang, Chun-Song CS and 14 more authors..  (2017)  Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9..  Molecular cell,  (18): [PMID:28525742]

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