| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab095284-10μg |
10μg |
现货  |
| |
| Ab095284-50μg |
50μg |
现货 |
| |
| Ab095284-100μg |
100μg |
现货 |
| |
| Ab095284-1mg |
1mg |
期货 |
|
| 产品名称 | CD74 Mouse mAb |
|---|---|
| 别名 | CD74单克隆抗体 | CD74小鼠单克隆抗体 | CD74小鼠单抗 |
| 英文别名 | CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated) | CD74 antigen | CD74 molecule, major histocompatibility complex, class II invariant chain | CD74 | CLIP | DHLAG | DHLAGgamma chain of class II antigens | |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | CD74 |
| 种属反应性 | 人(Human) |
| 免疫原 | SU-DHL-4 cells. |
| 阳性对照 | Flow: Human peripheral blood lymphocytes. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | LN2 |
| Format | Whole IgG |
| 亚型 | Mouse IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, pH 7.2-7.4 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。 |
| 分子类型 | 抗体 |
CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD74 (red) with CD74 Mouse mAb (Ab095284) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 (red) with CD74 Mouse mAb (Ab095284) conjugated with biotin at 2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 with CD74 Mouse mAb (Ab095284) conjugated with biotin (right panel) at 2 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | 1μg/100w cells |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0404673 |
分析证书 | 25-01-16 | Ab095284 |
| ZJ24F0404674 |
分析证书 | 25-01-16 | Ab095284 |
| ZJ24F0404675 |
分析证书 | 25-01-16 | Ab095284 |
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| 2. Claesson L, Larhammar D, Rask L, Peterson PA. (1983) cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure.. Proc Natl Acad Sci USA, 80 (24): (7395-9). [PMID:6324166] |
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| 5. Alissa A Hare,Lin Leng,Sunilkumar Gandavadi,Xin Du,Zoe Cournia,Richard Bucala,William L Jorgensen. (2010-08-24) Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF).. Bioorganic & medicinal chemistry letters, 20 ((19)): (5811-5814). [PMID:20728358] |
| 6. William L Jorgensen,Alexander Trofimov,Xin Du,Alissa A Hare,Lin Leng,Richard Bucala. (2011-07-02) Benzisothiazolones as modulators of macrophage migration inhibitory factor.. Bioorganic & medicinal chemistry letters, 21 ((15)): (4545-4549). [PMID:21719283] |
| 7. Cournia Z, Leng L, Gandavadi S, Du X, Bucala R, Jorgensen WL.. (2009) Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening.. J Med Chem, 52 (2): (416-424). [PMID:19090668] [10.1021/jm801100v] |
| 8. Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R.. (2010) Receptor agonists of macrophage migration inhibitory factor.. Bioorg Med Chem Lett, 20 (23): (7033-7036). [PMID:20971005] [10.1016/j.bmcl.2010.09.118] |
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| 14. Guncar, G G, Pungercic, G G, Klemencic, I I, Turk, V V and Turk, D D.. (1999) Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.. The EMBO journal, (15): [PMID:10022822] |
| 15. Charest, Alain A and 6 more authors.. (2003) Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21).. Genes, chromosomes & cancer, [PMID:12661006] |
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