Recombinant BCRP/ABCG2 Antibody

    应用:
  • WB
功能和特点
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab090883-10μl
10μl 现货 Stock Image
Ab090883-50μl
50μL 现货 Stock Image
Ab090883-100μl
100μL 期货 Stock Image
Ab090883-1ml
1ml 期货 Stock Image

基本信息

产品名称 Recombinant BCRP/ABCG2 Antibody
别名 ATP结合盒转运蛋白G2抗体 | ATP结合盒转运蛋白G2单克隆抗体 | ATP结合盒转运蛋白G2重组单克隆抗体 | BCRP抗体 | BCRP单克隆抗体 | BCRP重组单克隆抗体 | ABCG2抗体 | ABCG2单克隆抗体 | ABCG2重组单克隆抗体
英文别名 ATP-binding cassette sub-family G member 2 | Breast cancer resistance protein | CDw338 | EC 7.6.2.2 | Mitoxantrone resistance-associated protein | Placenta-specific ATP-binding cassette transporter | Urate exporter | ABC transporter antibody | ABC15 antib
规格或纯度 重组, ExactAb™, 已验证, 见COA
生化机理 Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
宿主种属 兔(Rabbit)
特异性 ABCG2
种属反应性 人(Human)
预测反应种属 恒河猴(Rhesus Macaque)
免疫原 A synthetic peptide derived from human BCRP/ABCG2 (AA 150-200).
阳性对照 WB: HEK293, HeLa, Jurkat, Hep G2 and MCF7 cell lysates.
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Rabbit IgG
轻链亚型 kappa
SDS-PAGE 150kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂 0.02% Sodium azide
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融。
分子类型 抗体

图片

Recombinant BCRP/ABCG2 Antibody (Ab090883) - Western Blot
All lanes: Recombinant BCRP/ABCG2 Antibody (Ab090883) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 72 kDa
Observed band size: 75 kDa
Exposure time: 30.0 s

关联靶点(人)

ABCG2 Tchem ATP 结合盒亚家族 G 成员 2(ATP-binding cassette sub-family G member 2) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
WB

1/500-1/2000

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到2个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0708380 分析证书 24-07-17 Ab090883
ZJ24F0708379 分析证书 24-07-17 Ab090883

参考文献

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