产品名称	Recombinant NT-proBNP Antibody
别名	重组NT-proBNP抗体
英文别名	Brain natriuretic factor prohormone \| Gamma-brain natriuretic peptide \| Iso-ANP \| preproBNP \| proBNP
规格或纯度	无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	山羊(Goat)
特异性	NT-proBNP
应用	ELISA,CLIA,LF,GICA,Capture antibody,FIA
种属反应性	人(Human)
免疫原	E. coli-derived recombinant human NT-proBNP (His27-His134)
偶联	Unconjugated

产品属性

抗体类型	Primary antibody
克隆类型	重组抗体
克隆号	1B8
Format	Whole IgG
亚型	IgG1
SDS-PAGE	150kDa
纯化方法	Protein A purified
配对抗体	[Ab007709] NT-proBNP Mouse mAb
来源	CHO supernatant
物理外观	Liquid
储存缓冲液	10mM PB+150mM NaCl+0.1% ProClin300, pH7.4
防腐剂	0.1% ProClin300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -20±5℃ for three years. Avoid freeze/thaw.
分子类型	抗体

图片

Binding ELISA: Recombinant NT-proBNP Antibody (Ab008412)

Recombinant NT-proBNP Antibody (Ab008412) - Binding ELISA
The binding activity of recombinant NT-proBNP Antibody with NT-proBNP antigen.

NT-proBNP Standard Curve with Antibody Pair (Ab008412 & Ab007709) in CLIA

NT-proBNP Standard Curve with Antibody Pair (Ab008412 & Ab007709) in CLIA

· Capture antibody: Recombinant NT-proBNP Antibody (Ab008412) at 1.0 μg/mL.

· Detection antibody: NT-proBNP Mouse mAb (Ab007709) at 1.0 μg/mL.

· Linear Range: 5-35000 pg/mL, R ≥ 0.99.

NT-proBNP Standard Curve with Antibody Pair (Ab008412 & Ab007709) in FLFIA

NT-proBNP Standard Curve with Antibody Pair (Ab008412 & Ab007709) in FLFIA

· Capture antibody: Recombinant NT-proBNP Antibody (Ab008412) at 1.0 mg/mL.

· Detection antibody: NT-proBNP Mouse mAb (Ab007709) at 1.0 mg/mL.

· Linear Range: 0-35000 pg/mL, LLOD: 50 pg/mL.

关联靶点（人）

NPPB Tbio 利钠肽B(Natriuretic peptides B) (0 活性数据)

点击查看靶蛋白信息： NPPB

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

安全和危险性（GHS）

SDS英文版

质量标准

质量标准

应用

应用名称	稀释比例
ELISA	1 μg/mL
CLIA	10-40μg/mg Beads
LF/GICA	1 mg/mL

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F1012183	分析证书	24-10-16	Ab008412
ZJ23F0700543	分析证书	23-07-06	Ab008412
ZJ23F0700542	分析证书	23-07-06	Ab008412

可替换产品

参考文献

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al.. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res, 14 (10B): (2121-7). [PMID:15489334]
2. Koller, K J KJ and 6 more authors.. (1991) Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).. Science (New York, N.Y.), (5): [PMID:1672777]
3. Kambayashi, Y Y and 8 more authors.. (1990) Isolation and sequence determination of human brain natriuretic peptide in human atrium.. FEBS letters, (1): [PMID:2136732]
4. Hino, J J, Tateyama, H H, Minamino, N N, Kangawa, K K and Matsuo, H H.. (1990) Isolation and identification of human brain natriuretic peptides in cardiac atrium.. Biochemical and biophysical research communications, (16): [PMID:2138890]
5. Sudoh, T T and 5 more authors.. (1989) Cloning and sequence analysis of cDNA encoding a precursor for human brain natriuretic peptide.. Biochemical and biophysical research communications, (31): [PMID:2522777]
6. Seilhamer, J J JJ and 6 more authors.. (1989) Human and canine gene homologs of porcine brain natriuretic peptide.. Biochemical and biophysical research communications, (15): [PMID:2597152]
7. Jensen, K T KT, Carstens, J J and Pedersen, E B EB.. (1998) Effect of BNP on renal hemodynamics, tubular function and vasoactive hormones in humans.. The American journal of physiology, [PMID:9458824]
8. Yan, W W, Wu, F F, Morser, J J and Wu, Q Q.. (2000) Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme.. Proceedings of the National Academy of Sciences of the United States of America, (18): [PMID:10880574]
9. Ohta, Y Y and 12 more authors.. (2000) Carvedilol enhances atrial and brain natriuretic peptide mRNA expression and release in rat heart.. Journal of cardiovascular pharmacology, [PMID:11206715]
10. Richards, A M AM and 9 more authors.. (2001) Plasma N-terminal pro-brain natriuretic peptide and adrenomedullin: prognostic utility and prediction of benefit from carvedilol in chronic ischemic left ventricular dysfunction. Australia-New Zealand Heart Failure Group.. Journal of the American College of Cardiology, (1): [PMID:11401111]
11. Frantz, Robert P RP and 11 more authors.. (2005) Carvedilol therapy is associated with a sustained decline in brain natriuretic peptide levels in patients with congestive heart failure.. American heart journal, [PMID:15864245]
12. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414]
13. He, Xiao-lin XL, Dukkipati, Abhiram A and Garcia, K Christopher KC.. (2006) Structural determinants of natriuretic peptide receptor specificity and degeneracy.. Journal of molecular biology, (25): [PMID:16870210]
14. Lam, Carolyn S P CS, Burnett, John C JC, Costello-Boerrigter, Lisa L, Rodeheffer, Richard J RJ and Redfield, Margaret M MM.. (2007) Alternate circulating pro-B-type natriuretic peptide and B-type natriuretic peptide forms in the general population.. Journal of the American College of Cardiology, (20): [PMID:17367664]
15. Ralat, Luis A LA and 6 more authors.. (2011) Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response.. The Journal of biological chemistry, (11): [PMID:21098034]
16. Keane, Fiona M FM, Nadvi, Naveed A NA, Yao, Tsun-Wen TW and Gorrell, Mark D MD.. (2011) Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α.. The FEBS journal, [PMID:21314817]
17. Peng, Jianhao J and 5 more authors.. (2011) Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.. Biochemical and biophysical research communications, (5): [PMID:21763278]
18. Huntley, Brenda K and 5 more authors.. (2015) Pro-B-type natriuretic peptide-1-108 processing and degradation in human heart failure.. Circulation. Heart failure, [PMID:25339504]

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体积（添加到小瓶中）

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所需的复溶浓度

Recombinant NT-proBNP Antibody

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

图片

关联靶点（人）

安全和危险性（GHS）

质量标准

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

可替换产品

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器