PLA2G7 Mouse mAb

    应用:
  • Detection Antibody
  • ELISA
  • FIA
  • GICA
功能和特点
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: 18A6
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab008129-10μg
10μg 现货 Stock Image
Ab008129-50μg
50μg 现货 Stock Image
Ab008129-100μg
100μg 现货 Stock Image
Ab008129-1mg
1mg 期货 Stock Image

基本信息

产品名称 PLA2G7 Mouse mAb
别名 PLA2G7 小鼠 mAb
英文别名 1-alkyl-2-acetylglycerophosphocholine esterase | 2-acetyl-1-alkylglycerophosphocholine esterase | EC 3.1.1.47 | Group-VIIA phospholipase A2 | gVIIA-PLA2 | LDL-associated phospholipase A2 | LDL-PLA(2) | PAF 2-acylhydrolase | PAF acetylhydrolase
规格或纯度 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属 小鼠(Mouse)
特异性 Human LP-PLA2
应用 GICA,Detection antibody,FIA
种属反应性 人(Human)
免疫原 E. coli-derived recombinant human LP-PLA2 (Phe22-Asn441)
偶联 Unconjugated

产品属性

抗体类型 Primary antibody
克隆类型 单克隆抗体
克隆号 18A6
Format Whole IgG
亚型 IgG1
SDS-PAGE 150 kDa
纯化方法 Caprylic acid precipitation
配对抗体 [Ab008130] PLA2G7 Mouse mAb as capture antibody in GICA, FIA
来源 Hybridoma supernatant
物理外观 Liquid
储存缓冲液 10mM PB+150mM NaCl+0.1% ProClin 300, pH7.4
防腐剂 0.1% ProClin 300
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Store at -20±5℃ for three years. Avoid freeze/thaw.
分子类型 抗体

图片

PLA2G7 Standard Curve with Antibody Pair (Ab008129 & Ab008130) in GICA

· Capture antibody: PLA2G7 Mouse mAb (Ab008129) at 1.0 mg/mL. 

· Detection antibody: PLA2G7 Mouse mAb (Ab008130) at 1.0 mg/mL.

· Linear Range: 0-1000 ng/mL.

关联靶点(人)

PLA2G7 Tchem 血小板活化因子乙酰水解酶(Platelet-activating factor acetylhydrolase) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
GICA/FIA

1mg/ml

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1012080 分析证书 24-10-14 Ab008129
ZJ23F0500236 分析证书 23-06-05 Ab008129
ZJ23F0500237 分析证书 23-06-05 Ab008129

参考文献

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3. Tjoelker LW, Wilder C, Eberhardt C, Stafforini DM, Dietsch G, Schimpf B, Hooper S, Le Trong H, Cousens LS, Zimmerman GA et al..  (1995)  Anti-inflammatory properties of a platelet-activating factor acetylhydrolase..  Nature,  374  (6522): (549-53).  [PMID:7700381]
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11. Liu Q, Chen X, Chen W, Yuan X, Su H, Shen J, Xu Y..  (2016)  Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors..  J Med Chem,  59  (10): (5115-5120).  [PMID:27078579] [10.1021/acs.jmedchem.6b00282]
12. Tjoelker, L W LW and 8 more authors..  (1995)  Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad..  The Journal of biological chemistry,  (27): [PMID:7592717]
13. Tew, D G DG and 8 more authors..  (1996)  Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins..  Arteriosclerosis, thrombosis, and vascular biology,  [PMID:8624782]
14. Stafforini, D M DM and 11 more authors..  (1996)  Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase..  The Journal of clinical investigation,  (15): [PMID:8675689]
15. Yamada, Y Y and Yokota, M M..  (1997)  Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation..  Biochemical and biophysical research communications,  (30): [PMID:9245731]
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17. Yamada, Y Y, Ichihara, S S, Fujimura, T T and Yokota, M M..  (1998)  Identification of the G994--> T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men..  Metabolism: clinical and experimental,  [PMID:9472966]
18. Yoshida, H H and 7 more authors..  (1998)  A mutation in plasma platelet-activating factor acetylhydrolase (Val279Phe) is a genetic risk factor for cerebral hemorrhage but not for hypertension..  Thrombosis and haemostasis,  [PMID:9759612]
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20. Kriska, Tamas T, Marathe, Gopal K GK, Schmidt, Jacob C JC, McIntyre, Thomas M TM and Girotti, Albert W AW..  (2007)  Phospholipase action of platelet-activating factor acetylhydrolase, but not paraoxonase-1, on long fatty acyl chain phospholipid hydroperoxides..  The Journal of biological chemistry,  (5): [PMID:17090529]
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