Recombinant Hemoglobin A1c Antibody

    应用:
  • Detection Antibody
  • ELISA
  • FIA
功能和特点
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: 35F6
  • 偶联: Unconjugated
有货

库存信息

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库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
Ab008123-10μg
10μg 现货 Stock Image
Ab008123-50μg
50μg 现货 Stock Image
Ab008123-100μg
100μg 现货 Stock Image
Ab008123-1mg
1mg 期货 Stock Image

基本信息

产品名称 Recombinant Hemoglobin A1c Antibody
别名 重组糖化血红蛋白抗体
英文别名 Beta-globin | Hemoglobin beta chain
规格或纯度 ExactAb™, Validated, Carrier Free, Azide Free, Recombinant, 5.07mg/mL
宿主种属 小鼠(Mouse)
特异性 HBA1C
应用 ELISA,Detection antibody,FIA
种属反应性 人(Human)
免疫原 E. coli-derived recombinant human HBA1C
偶联 Unconjugated

产品属性

抗体类型 Primary antibody
克隆类型 重组抗体
克隆号 35F6
Format Whole IgG
亚型 Mouse IgG1
SDS-PAGE 150 kDa
纯化方法 Protein A
配对抗体 [Ab008124] Hemoglobin A1c (HbA1c) Antibody as Capture antibody in ELISA, FIA
来源 CHO supernatant
物理外观 Liquid
储存缓冲液 10mM PB+150mM NaCl+0.1% P300, pH7.4
防腐剂 0.1% ProClin 300
浓度 5.07mg/mL
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Storage at -20℃±5℃ for three storage. Avoid repeated freeze / thaw cycles.
分子类型 抗体

关联靶点(人)

HBB Tbio 血红蛋白亚基 β(Hemoglobin subunit beta) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
FIA

1 mg/mL

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1011971 分析证书 24-10-14 Ab008123
ZJ23F0500248 分析证书 23-06-02 Ab008123
ZJ23F0500250 分析证书 23-06-02 Ab008123

参考文献

1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al..  (2004)  Complete sequencing and characterization of 21,243 full-length human cDNAs..  Nat Genet,  36  (1): (40-5).  [PMID:14702039]
2. Watterson SH, Liu Q, Beaudoin Bertrand M, Batt DG, Li L, Pattoli MA, Skala S, Cheng L, Obermeier MT, Moore R et al..  (2019)  Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)..  J Med Chem,  62  (7): (3228-3250).  [PMID:30893553]
3. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge.  (2011-01-29)  Initial characterization of the human central proteome..  BMC systems biology,  (17-17).  [PMID:21269460]
4. Pagare PP, Ghatge MS, Musayev FN, Deshpande TM, Chen Q, Braxton C, Kim S, Venitz J, Zhang Y, Abdulmalik O, Safo MK..  (2018)  Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease..  Bioorg Med Chem,  26  (9): (2530-2538).  [PMID:29655608] [10.1016/j.bmc.2018.04.015]
5. Brimhall, B B and 5 more authors..  (1975)  Two new hemoglobins. Hemoglobin Alabama (beta39(C5)Gln leads to Lys) and hemoglobin Montgomery (alpha 48(CD 6) Leu leads to Arg)..  Biochimica et biophysica acta,  (30): [PMID:1115799]
6. and Fermi, G G..  (1975)  Three-dimensional fourier synthesis of human deoxyhaemoglobin at 2-5 A resolution: refinement of the atomic model..  Journal of molecular biology,  (15): [PMID:1177322]
7. Wajcman, H H and 7 more authors..  (1992)  Two new human hemoglobin variants caused by unusual mutational events: Hb Zaïre contains a five residue repetition within the alpha-chain and Hb Duino has two residues substituted in the beta-chain..  Human genetics,  [PMID:1511986]
8. Ramachandran, M M and 7 more authors..  (1992)  A new variant, HB Muscat [alpha 2 beta (2)32(B14)Leu----Val] observed in association with HB S in an Arabian family..  Hemoglobin,  [PMID:1517102]
9. Como, P F PF and 7 more authors..  (1991)  Hb Geelong [beta 139(H17)Asn----Asp]..  Hemoglobin,  [PMID:1917539]
10. Bardakdjian-Michau, J J and 9 more authors..  (1990)  Hemoglobin Dhonburi alpha 2 beta 2 126 (H4) Val----Gly: a new unstable beta variant producing a beta-thalassemia intermedia phenotype in association with beta zero-thalassemia..  American journal of hematology,  [PMID:2399911]
11. Lang, K M KM and Spritz, R A RA..  (1985)  Cloning specific complete polyadenylylated 3'-terminal cDNA segments..  Gene,  [PMID:2581851]
12. Ohba, Y Y and 9 more authors..  (1985)  A new unstable, high oxygen affinity hemoglobin: Hb Nagoya or beta 97 (FG4) His----Pro..  Hemoglobin,  [PMID:3838976]
13. Benz, E J EJ and 7 more authors..  (1981)  Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys)..  The Journal of clinical investigation,  [PMID:6166632]
14. Moo-Penn, W F WF, Johnson, M H MH, McGuffey, J E JE and Jue, D L DL..  (1984)  Hemoglobin Shelby [beta 131(H9) Gln----Lys] a correction to the structure of hemoglobin Deaconess and hemoglobin Leslie..  Hemoglobin,  [PMID:6526653]
15. Randhawa, Z I ZI, Jones, R T RT and Lie-Injo, L E LE..  (1984)  Human hemoglobin Portland II (zeta 2 beta 2). Isolation and characterization of Portland hemoglobin components and their constituent globin chains..  The Journal of biological chemistry,  (10): [PMID:6539334]
16. Nakatsuji, T T and 8 more authors..  (1981)  Hemoglobin Miyashiro (beta 23[B5] val substituting for gly) an electrophoretically silent variant discovered by the isopropanol test..  Hemoglobin,  [PMID:7338468]
17. Shapiro, R R, McManus, M J MJ, Zalut, C C and Bunn, H F HF..  (1980)  Sites of nonenzymatic glycosylation of human hemoglobin A..  The Journal of biological chemistry,  (10): [PMID:7358733]
18. and Baldwin, J M JM..  (1980)  The structure of human carbonmonoxy haemoglobin at 2.7 A resolution..  Journal of molecular biology,  (15): [PMID:7373648]
19. Fay, K C KC and 7 more authors..  (1993)  Haemoglobin Manukau beta 67[E11] Val-->Gly: transfusion-dependent haemolytic anaemia ameliorated by coexisting alpha thalassaemia..  British journal of haematology,  [PMID:8280608]
20. Suzuki, H H and 5 more authors..  (1993)  Globin chain synthesis in hemolytic anemia reticulocytes. A case of hemoglobin Burke..  Biochemistry and molecular biology international,  [PMID:8401300]
21. Harrington, D J DJ, Adachi, K K and Royer, W E WE..  (1998)  Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber..  The Journal of biological chemistry,  (4): [PMID:9830011]
22. Deutsch, S S and 6 more authors..  (1999)  Hb Iraq-Halabja beta10 (A7) Ala-->Val (GCC-->GTC): a new beta-chain silent variant in a family with multiple Hb disorders..  American journal of hematology,  [PMID:10398311]
23. Kidd, R D RD, Russell, J E JE, Watmough, N J NJ, Baker, E N EN and Brittain, T T..  (2001)  The role of beta chains in the control of the hemoglobin oxygen binding function: chimeric human/mouse proteins, structure, and function..  Biochemistry,  (25): [PMID:11747442]
24. Chen, X X, Ji, Z L ZL and Chen, Y Z YZ..  (2002)  TTD: Therapeutic Target Database..  Nucleic acids research,  (1): [PMID:11752352]
25. Sawangareetrakul, Phannee P and 6 more authors..  (2002)  Double heterozygosity for Hb Pyrgos [beta83(EF7)Gly-->Asp] and Hb E [beta26(B8)Glu-->Lys] found in association with alpha-thalassemia..  Hemoglobin,  [PMID:12144064]
26. Williamson, Angela L AL and 11 more authors..  (2003)  Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion..  The Journal of infectious diseases,  (1): [PMID:12552433]
27. BRAUNITZER, G G and 6 more authors..  (1961)  [The structure of normal adult human hemoglobins]..  Hoppe-Seyler's Zeitschrift fur physiologische Chemie,  (20): [PMID:13872627]
28. Flatz, Gebhard G, Sanguansermsri, Torpong T, Sengchanh, Sourideth S, Horst, David D and Horst, Jürgen J..  (2004)  The 'hot-spot' of Hb E [beta26(B8)Glu-->Lys] in Southeast Asia: beta-globin anomalies in the Lao Theung population of southern Laos..  Hemoglobin,  [PMID:15481886]
29. Wood, Elizabeth T ET, Stover, Daryn A DA, Slatkin, Montgomery M, Nachman, Michael W MW and Hammer, Michael F MF..  (2005)  The beta -globin recombinational hotspot reduces the effects of strong selection around HbC, a recently arisen mutation providing resistance to malaria..  American journal of human genetics,  [PMID:16175509]
30. Kim, S Y SY and 6 more authors..  (2010)  A novel hemoglobin variant beta135(H13) Ala > Asp identified in an asymptomatic Korean family by direct sequencing: suggesting a new insight into Hb Beckman mutation..  International journal of laboratory hematology,  [PMID:19453576]
31. Safo, Martin K MK and 6 more authors..  (2013)  Structure of fully liganded Hb ζ2β2s trapped in a tense conformation..  Acta crystallographica. Section D, Biological crystallography,  [PMID:24100324]
32. Bian, Yangyang Y and 9 more authors..  (2014)  An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome..  Journal of proteomics,  (16): [PMID:24275569]
33. Mañú Pereira, María Del Mar MD, Ropero, Paloma P, Loureiro, Carmen C and Vives Corrons, Joan-Lluis JL..  (2017)  Low affinity hemoglobinopathy (Hb Vigo) due to a new mutation of beta globin gene (c200 A>T; Lys>Ile). A cause of rare anemia misdiagnosis..  American journal of hematology,  [PMID:28066926]

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